Gene Information

Name : guaA (HYPDE_27118)
Accession : YP_007913602.1
Strain : Hyphomicrobium denitrificans 1NES1
Genome accession: NC_021172
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 906174 - 907721 bp
Length : 1548 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
TTGACCGACAGCGTTCTCATCATCGATTTCGGCAGCCAAGTTACGCAGCTCATCGCGCGCCGCGTGCGCGAGGGGGGCGT
CTACTCGGAAATCCATCCCTACCAGAGCGCCGCCGAAGCGTTTGCCAAGCTCAAGCCGAAAGCTGTCATTCTTTCCGGCG
GTCCCGCGTCGGTGACGGAGGCGGGGTCTCCGCGCGCTCCGGATGGGGTTTTTTCGTCGGGCGTGCCGGTGCTCGGTATC
TGTTACGGCCAGCAGACCATGGCGGAGCAGCTCGGCGGCAAGGTCGAGGCAGGGCACCATCGGGAGTTCGGGCGGGCGTT
TCTGTCCATCGATAAGCCGAGCCCGCTGTTCGACGGATTTTGGTCGCCGGGGACGCGCCATCAAGTCTGGATGAGCCACG
GTGATCGCGTGACGCGCCTGCCGGACGGATTTCAGGTTATCGCGACGAGCGAGAACGCGCCGTTCGCGGCGGTCGCCGAC
GAAGACCGGCATTTCTACGCCGTGCAGTTTCATCCCGAGGTGGTTCATACGCCGAATGGCGCGAAGCTGATCTCAAACTT
CGTCCATAAGATTGCGGGGCTGAAGTCCGACTGGACGATGGCGGCCTACCGGCGTGTGATGATCGACAAGATCAGGGCGC
AGGTCGGCAAAGGCCGGGTCATTTGCGGCCTGTCGGGTGGTGTCGACAGCGCCGTCGCGGCCGTCCTCATTCATGAGGCT
ATCGGCGATCAGCTCACCTGCGTGTTCGTCGATCACGGTTTGATGCGTTTGGGCGAGGCGGATGAAGTGGTCCGGCTGTT
CCGCGACCACTACAACATTCCACTCGTTCACGTCGACGCTTCCGAGCAATTCCTCAATGCGCTCGCCAGGGTTTCCGATC
CGGAGACGAAGCGCAAGACGATCGGCAAGCACTTTATCGATGTCTTCGAGACGGAAGCGAAGAAGATCGGCGGCGCCGAT
TTCCTTGCTCAAGGGACGCTTTATCCGGACGTCATCGAAAGCGTGTCGTTCACCGGCGGGCCCTCGGTGACGATCAAATC
TCACCACAACGTCGGCGGCTTGCCCGAGCGCATGCACATGAAGCTCGTCGAGCCGCTGCGCGAACTTTTCAAGGACGAGG
TTCGCGCGCTCGGTCGCGAGCTTGACCTGCCGGAAGCATTTGTCGGGCGCCATCCCTTCCCGGGCCCGGGGCTCGCCATC
CGCATTCCGGGTGAGATCACACGCGAGAAGCTCGACATTCTGCGCCAAGCCGATGCGATCTATCTCGATGAGATCCGCAA
GGCCGGTCTTTATGATGCCATCTGGCAGGCGTTCGCCGTATTGCTTCCCGTTCGTACTGTCGGCGTCATGGGCGACGGCC
GGACATACGATCATGTCCTGGGACTCAGAGCAGTCACGTCCGTCGATGGAATGACGGCGGACTTCTTCCATTTCGACATG
GCGTTTCTCGGCCGCGTCGCGACGCGCATCATCAACGAGGTTCGCGGCGTCAACCGCGTCGTCTACGATGTGACGTCAAA
GCCTCCCGGCACGATCGAGTGGGAATGA

Protein sequence :
MTDSVLIIDFGSQVTQLIARRVREGGVYSEIHPYQSAAEAFAKLKPKAVILSGGPASVTEAGSPRAPDGVFSSGVPVLGI
CYGQQTMAEQLGGKVEAGHHREFGRAFLSIDKPSPLFDGFWSPGTRHQVWMSHGDRVTRLPDGFQVIATSENAPFAAVAD
EDRHFYAVQFHPEVVHTPNGAKLISNFVHKIAGLKSDWTMAAYRRVMIDKIRAQVGKGRVICGLSGGVDSAVAAVLIHEA
IGDQLTCVFVDHGLMRLGEADEVVRLFRDHYNIPLVHVDASEQFLNALARVSDPETKRKTIGKHFIDVFETEAKKIGGAD
FLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMHMKLVEPLRELFKDEVRALGRELDLPEAFVGRHPFPGPGLAI
RIPGEITREKLDILRQADAIYLDEIRKAGLYDAIWQAFAVLLPVRTVGVMGDGRTYDHVLGLRAVTSVDGMTADFFHFDM
AFLGRVATRIINEVRGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-139 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-139 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-124 54