Gene Information

Name : HYPDE_34548 (HYPDE_34548)
Accession : YP_007915080.1
Strain : Hyphomicrobium denitrificans 1NES1
Genome accession: NC_021172
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2368797 - 2370317 bp
Length : 1521 bp
Strand : -
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGCAGCATGTTGCGATGGATAAACTTAAAGGCCGGCAAGTCATCAAGGCTCGCTACGACAACTTCATCGGAGGCAAGTG
GGTCGCCCCTGTTCGTGGACAGTATTTTACGAACGTCACTCCGATTACCGGTCAGCCCGTTTGCGAAATTGCGCGCTCGA
CAGCTGAGGACATCGAACTAGCTCTTGATGCCGCTCACAAAGTCCGTGAGTCCTGGGGCAACACTTCTCCGGCAGCGCGG
GCTCGCGTCCTGGCGAAGATCGCGACGAGGATGGAAGAGAACCTGGACGTTCTGGCGCTCGTCGAGACGATCGACAACGG
CAAGCCGATCCGCGAGACAACGCACGCCGACTTGCCGCTCGCGGTCGATCATTTCCGTTATTTCGCTGGCTGCCTGCGAG
CACAGGAAGGTTCGATTTCCGAGATCGATCACGATACGATCGCGTATCATTTCCATGAACCGCTCGGTGTCGTCGGCCAG
ATCATTCCATGGAACTTCCCGCTGTTGATGGCGGTTTGGAAGCTCGCGCCTGCGCTTGCCGCTGGCAACTGCGTGATCCT
GAAACCTGCCGAGCAGACGCCGATGTCGATCATGGTTCTGATGGACATCATCGGCGATCTTCTTCCCGAAGGCGTCCTCA
ATGTCGTCAATGGCTTTGGCGTCGAAGCGGGTAAGCCCCTCGCTCAGAACAAGCGCATCGCGAAGATCGCCTTCACCGGC
GAGACGACGACCGGCCGCTTGATCATGCAGTATGCATCGGAAAACATAATCCCGTGCACGCTGGAGCTCGGCGGCAAGTC
GCCGAACATCTTCTTCGCGGACGTGATGGACGCGGACGACGAATACTTCGACAAGTGCCTCGAAGGCTTCACGATGTTCG
CCCTGAACCAGGGTGAAGTTTGCACCTGCCCGAGCCGCGCGCTGATCCAGCGTTCGATTTATGAGAAATTCATGGAACGG
GCTTTGCAGCGTGTCGTGAAGATCAAACAGGGCCATCCGATGGATGCCACCACGATGATCGGCGCTCAGGCCTCGAACGA
TCAGCTTGAGAAGATTTTGAGTTACATCGAGATCGGCAAGGGCGAGGGTGCGCGCGTGTTGACGGGCGGCAAGCGCGCCA
ACCTCGGCGGCGAGCTATCGTCGGGCTATTACGTCGAACCGACGGTTCTTGAAGGCCACAACAAGATGCGCGTCTTCCAG
GAAGAAATTTTTGGACCCGTCCTTGCGGTCACGACCTTCGAGGACGATGCGGAAGCGCTCGCGATCGCCAACGACACGCT
CTATGGTCTCGGATCAGGCGTCTGGACCCGCAACGGCACGCGCGCCTATCGCATAGGCCGAGGCATCCAGGCCGGCCGCG
TCTGGACCAACTGCTATCACGCCTATCCTGCGCATGCTGCGTTCGGTGGCTACAAGATGTCGGGTATCGGCCGCGAAACG
CACAAGATGATGCTCGATCACTATCAGCAGACGAAGAACCTGCTCGTCAGCTACAGCCCGAAGGCGCTCGGCTTCTTCTG
A

Protein sequence :
MQHVAMDKLKGRQVIKARYDNFIGGKWVAPVRGQYFTNVTPITGQPVCEIARSTAEDIELALDAAHKVRESWGNTSPAAR
ARVLAKIATRMEENLDVLALVETIDNGKPIRETTHADLPLAVDHFRYFAGCLRAQEGSISEIDHDTIAYHFHEPLGVVGQ
IIPWNFPLLMAVWKLAPALAAGNCVILKPAEQTPMSIMVLMDIIGDLLPEGVLNVVNGFGVEAGKPLAQNKRIAKIAFTG
ETTTGRLIMQYASENIIPCTLELGGKSPNIFFADVMDADDEYFDKCLEGFTMFALNQGEVCTCPSRALIQRSIYEKFMER
ALQRVVKIKQGHPMDATTMIGAQASNDQLEKILSYIEIGKGEGARVLTGGKRANLGGELSSGYYVEPTVLEGHNKMRVFQ
EEIFGPVLAVTTFEDDAEALAIANDTLYGLGSGVWTRNGTRAYRIGRGIQAGRVWTNCYHAYPAHAAFGGYKMSGIGRET
HKMMLDHYQQTKNLLVSYSPKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-152 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-158 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-158 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-158 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-157 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HYPDE_34548 YP_007915080.1 aldehyde dehydrogenase VFG0082 Protein 7e-153 62