Gene Information

Name : HYPDE_32908 (HYPDE_32908)
Accession : YP_007914753.1
Strain : Hyphomicrobium denitrificans 1NES1
Genome accession: NC_021172
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2039384 - 2040871 bp
Length : 1488 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACATCGCTCGCGCACTTTGAAGCGGTCGCCGGTTCGCTGAAACTTCCGGGCGAAGCCGTCATCGACGGCAAGCTTAC
AGCGAGCGCATCCGGCAAGACGTTTGCGAACGTGACGCCGCGGAACGGACGCGTACTGAACCAAGTTGCCCAGTGCGATG
CCGCAGACATCGATGCCGCGGTGAAAAGCGCCCGTCGCGCTTTCGAAGATGGGCAGTGGCGCAAGCTTCATTATCGCGAC
AAGAAGCGCGTGCTGTTCAGGCTCGCGGAACTTATGACACGCGAAGCCGAGGCGCTGGCCATCCTCGAAAGTCTCGACGT
CGGCAAGCCGATCACGAATGCACTTAAGGGTGATATTCCGGGCTCCATCCGGACGCTCGCCTATTATGCGGAAGCACTCG
ACAAGGTTTACGGCGAGGTCGGTCCCGAGGCACCCGACCGTTTCTCGTTCGCGGTCCACGAGCCGCTGGGCGTCGTCGGA
GCCATCGTACCGTGGAATTTTCCGCTGCTGATGGCGATGTGGAAGATCGCGCCGGCACTCGCGATGGGGAATTCCGTAGT
CCTGAAGCCGGCCGAGCAATCCCCCCTCACCGCTTTGAAGATCGGCGAACTGGCGCTCGAAGCCGGATTGCCGCCTGGCG
TGCTCAATGTGGTCCCCGGATTTGGCGCCGAAGCCGGCAAGGCATTGGGGCTTCACGACGACGTCGACATGATCGCGTTC
ACGGGTTCGGGGGCGGTCGGAAAATTGCTGATGCAGTATTCCGGTCAGAGCAACCTGAAACGCATCAGCCTCGAGCTTGG
CGGCAAATCTCCGCACATCATCTTCGCCGACTGTACCGATCTCGATAAAGCCGCGATGCAGGCGGCGTGGGGCATCTTTT
ACAATTCCGGCCAAGTCTGCACGGCGGGATCGCGTCTGCTCGTGCATGACGCAATCGCGGACCAATTTCTGGATCGGCTG
CTTGCCGTCGCCAGCAGGATTGTCGCCGGGGATCCTCTCGAACCGTCGACGAAAAGCGGCGCGATGGCGAGCGAAGAGCA
GATGAAAACGGCGCTGCGCTATATCGAGACGGCGAAGCGCGAAGGCGATGCGTTGACGCTCGGCGGCAACCGCACGCGCG
TCGATAGCGGCGGCTTCTACGTCGAGCCGACGGTATTCGACCGCGTCAAGCCGGAGAACACTTTGGCGCGCGAAGAAGTC
TTCGGCCCCGTGCTGGCCGTGACCCGCTTCAAGGAAGCAGACGAAGCCATCCGCATCGCCAACGACACAAACTACGGTCT
CGCCGCCGGGCTTTGGACGAAAGACATTTCGCTCGCCCATCGCGCCGCACGCGAAATCCGCGCCGGGCTCGTCTGGATCA
ACGGCTGGGATAGCTGCGATATTACGATGCCGTTTGGCGGCTTCAAGCAGTCGGGCTTCGGACGGGACCGCTCGCTGCAT
GCACTTCACAAATATGCCGACTTGAAGTCGGTCTCGATTACGCTCTGA

Protein sequence :
MTSLAHFEAVAGSLKLPGEAVIDGKLTASASGKTFANVTPRNGRVLNQVAQCDAADIDAAVKSARRAFEDGQWRKLHYRD
KKRVLFRLAELMTREAEALAILESLDVGKPITNALKGDIPGSIRTLAYYAEALDKVYGEVGPEAPDRFSFAVHEPLGVVG
AIVPWNFPLLMAMWKIAPALAMGNSVVLKPAEQSPLTALKIGELALEAGLPPGVLNVVPGFGAEAGKALGLHDDVDMIAF
TGSGAVGKLLMQYSGQSNLKRISLELGGKSPHIIFADCTDLDKAAMQAAWGIFYNSGQVCTAGSRLLVHDAIADQFLDRL
LAVASRIVAGDPLEPSTKSGAMASEEQMKTALRYIETAKREGDALTLGGNRTRVDSGGFYVEPTVFDRVKPENTLAREEV
FGPVLAVTRFKEADEAIRIANDTNYGLAAGLWTKDISLAHRAAREIRAGLVWINGWDSCDITMPFGGFKQSGFGRDRSLH
ALHKYADLKSVSITL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-112 51
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-85 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-85 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-85 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-85 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-84 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HYPDE_32908 YP_007914753.1 aldehyde dehydrogenase VFG0082 Protein 3e-85 42