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Name : ureC (AvCA_09880) Accession : YP_007892007.1 Strain : Azotobacter vinelandii CA Genome accession: NC_021149 Putative virulence/resistance : Virulence Product : urease subunit alpha Function : - COG functional category : - COG ID : - EC number : - Position : 938940 - 940640 bp Length : 1701 bp Strand : - Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alp DNA sequence : ATGAAAATCAGCAGACAAGCCTACGCTGACATGTTCGGCCCCACGCTCGGCGACCGGGTGCGCCTGGCCGACACCGAGTT GTGGATCGAGGTGGAGCAGGACTTCACCGTCTACGGCGAGGAAGTGAAGTTCGGCGGCGGCAAGGTGATCCGCGACGGCA TGGGCCAGGGCCAGTTGGAGAGCGCCGCGGTGGTCGACACCCTGATCACCAACGCGCTGATCCTCGACCACTGGGGCATC GTCAAGGCCGACGTCGGCCTCAAGGACGGGCGCATCGCCGCCATCGGCAAGGCCGGCAACCCGGACATCCAGCCGGGGGT GACCATCGCCGTCGGCGCCGCCACCGAGGTGATCGCCGGCGAGGGCATGATCCTCACCGCCGGCGGCATCGACAGCCACA TCCACTTCATCTGCCCGCAGCAGATCGAAGAGGCGCTGATGAGCGGCATCACCACCATGATCGGCGGCGGCACGGGACCG GCCACCGGCACCAACGCCACCACCGTCACGCCCGGTCCCTGGCACATCGCGCGCATGCTGCAGGCCGCCGACGCCTTCCC GATGAACCTGGGCTTCACCGGCAAGGGCAACGCCAGCCTGCCGGGCCCCCTGGCCGAGCAGATCGAAGCCGGCGCCATCG GCCTCAAGCTGCACGAGGACTGGGGCACCACCCCGGCGGCCATCGACAACTGCCTGTCCGTGGCCGACCGTTACGACGTG CAGGTGGCGATCCATACCGACACCCTCAACGAGTCCGGCTTCGTCGAGACCAGCCTGGCCGCCTTCAAGGACCGCACCAT CCACACCTACCACACCGAGGGCGCCGGCGGCGGCCACGCGCCGGACATCATCAAGGCCTGCGGCCTGCCCAACGTGCTGC CCAGCTCGACCAACCCGACCCGGCCGTTCACCCGCAACACCATCGACGAACACCTGGACATGCTGATGGTCTGCCACCAC CTCGATCCGAGCATCGCCGAGGACGTGGCCTTCGCGGAAAGCCGCATCCGCCGCGAGACCATCGCCGCCGAGGACATCCT CCACGACCTCGGCGCCTTCAGCATGATCTCCTCGGACAGCCAGGCCATGGGCCGGGTCGGCGAAGTGATCGTCCGCACCT GGCAGACCGCCGACAAGATGAAGAAACAGCGCGGCCCGCTGCCCGAGGACGTCGCCGGCCACGACAACTTCCGCGTCAAG CGCTACGTCGCCAAGTACACCATCAACCCGGCGATCACCCACGGCATCAGCCACGAGGTCGGCTCGGTGGAGGTCGGCAA GTGGGCCGACCTGGTGCTCTGGCGGCCGGCCTTCTTCGGCGTGAAACCCTCGCTGATCCTCAAGGGCGGCGCCATCGCCG CGAGCCTGATGGGCGACGCCAACGCCTCCATCCCCACCCCGCAGCCGGTGCACTACCGGCCGATGTTCGCCAGCTTCGCC GGCTCGCGCCACGCCACCAGCATCACCTTCGTCAGCCAGGCGGCGCTGGCCGCCGGGGTGCCGGAACGACTCGGTTTGCA CAAGCGCATCGGCGTGGTCAAGGGCTGCCGGAACGTGCGCAAGAAGGACCTGATCCACAACGGCGCCACCCCGACCATCG AGGTCGATCCGCAGACCTACCAGGTCAAGGCCGACGGCCAGTTGCTCTGGTGCGAACCGGCCGAGGTGCTGCCGCTGGCG CAGCGTTATTTCCTCTTTTGA Protein sequence : MKISRQAYADMFGPTLGDRVRLADTELWIEVEQDFTVYGEEVKFGGGKVIRDGMGQGQLESAAVVDTLITNALILDHWGI VKADVGLKDGRIAAIGKAGNPDIQPGVTIAVGAATEVIAGEGMILTAGGIDSHIHFICPQQIEEALMSGITTMIGGGTGP ATGTNATTVTPGPWHIARMLQAADAFPMNLGFTGKGNASLPGPLAEQIEAGAIGLKLHEDWGTTPAAIDNCLSVADRYDV QVAIHTDTLNESGFVETSLAAFKDRTIHTYHTEGAGGGHAPDIIKACGLPNVLPSSTNPTRPFTRNTIDEHLDMLMVCHH LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIVRTWQTADKMKKQRGPLPEDVAGHDNFRVK RYVAKYTINPAITHGISHEVGSVEVGKWADLVLWRPAFFGVKPSLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFA GSRHATSITFVSQAALAAGVPERLGLHKRIGVVKGCRNVRKKDLIHNGATPTIEVDPQTYQVKADGQLLWCEPAEVLPLA QRYFLF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ureC | NP_286680.1 | urease subunit alpha | Virulence | TAI | Protein | 0.0 | 73 |
| ureC | NP_287088.1 | urease subunit alpha | Not tested | TAI | Protein | 0.0 | 73 |
| ureC | YP_005684266.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 3e-163 | 63 |
| ureC | YP_005682174.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 4e-163 | 63 |
| ureC | YP_003784325.1 | urease subunit alpha | Not tested | PiCp 7 | Protein | 4e-163 | 63 |
| ureC | YP_005686358.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 4e-163 | 63 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ureC | YP_007892007.1 | urease subunit alpha | VFG0270 | Protein | 8e-161 | 66 |
