Gene Information

Name : guaA (AvCA_39720)
Accession : YP_007894893.1
Strain : Azotobacter vinelandii CA
Genome accession: NC_021149
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4020655 - 4022235 bp
Length : 1581 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCACCAAGACATCCACGCCCACCGGATCCTGATCCTGGATTTCGGTTCCCAGTACACCCAGTTGATCGCCCGCCG
GGTGCGCGAGATCGGCGTCTATTGCGAGCTGCACCCGTTCGACATGAGCAACGAGGAGATCCGCGCCTTCGCCCCGCGCG
GCATCATCCTCGCCGGCGGGCCGGAGTCGGTGCACGAGGCCGACAGTCCGCGCGCGCCGCAAGCGGTGTTCGATCTGGGC
GTGCCGCTTTTCGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAACTCGGCGGCAAGGTGCAAGGCTCGGATCTGCG
CGAGTTCGGCTATGCCCGTGTCGATGTGGTTGGCAAGGCGCGCCTGCTCGACGGCATCGAGGATCATGTGGACGACGACG
GCGTGCTCGGCCTCGACGTGTGGATGAGCCACGGCGACAAGGTCACCGGAATTCCCGAGGGCTTCCATGTGCTGGCCAGC
ACTCCGAGTTGCCCGATCGCCGCCATGGCCGACGACAAGCGCCGCTACTACGGCGTGCAGTTCCACCCGGAAGTGACCCA
CACCAAGCAGGGCCTGCGCATCCTCGGCCGCTTCGTGCGCGAGATCTGCGGCTGCGAGGCGCTGTGGACGCCATCCAACA
TCGTCGAGGACGCCATCGCCCAGGTGCGCGCCCAGGTCGGCGGCGCCAACGTGCTGCTCGGCCTTTCCGGCGGCGTCGAC
TCCTCGGTGGTCGCCGCGCTGCTGCATCGCGCCATCGGCGACCGGCTGACCTGCGTGTTCGTCGACAACGGCCTGCTGCG
CCTGCACGAGGGCGACCAGGTGATGGCCATGTTCGCCGAGAACATGGGCGTCAAGGTGATCCGCGCCGATGCCGAGGCGC
AGTTCCTCGCCAACCTGGCCGGCGTGTCCGACCCGGAGCAGAAGCGCAAGATCATCGGCCGCACCTTCATCGAAGTGTTC
GATGCCGAGGCGGCGAAGCTGGAGAACATCCGTTTCCTCGCCCAGGGCACCATCTATCCCGACGTGATCGAATCGGCCGG
CGCCAGGACCGGCAAGGCCCATGTGATCAAGTCCCACCACAACGTCGGCGGTCTGCCCGAGGACATGAACCTCAAGCTGG
TCGAGCCGCTGCGCGAACTGTTCAAGGACGAGGTGCGCAAGATCGGCCTGGAACTGGGCCTGCCCTACGACATGGTCTAT
CGCCACCCGTTCCCCGGTCCGGGCCTCGGGGTGCGCATCCTCGGCGAGGTGAAGAAGGAATACGCCGACCTGCTTCGCCG
CGCCGACCATATCTTCATCGAGGAACTGCGCAAGGCCGACTGGTACCACAAGGTCAGCCAGGCGTTCGTGGTGTTCCAGC
CGGTCAAGTCGGTCGGCGTGGTCGGCGACGGCCGCCGCTACGCCTGGGTGGTCGCCCTGCGCGCCGTGGAAACCGTCGAC
TTCATGACCGCCCGTTGGGCGCACCTGCCCTACGAGCTCCTGGAAAAAGTCTCCAACCGTATCATCAACGAGATCGACGG
CATCTCCCGGGTCACCTACGACGTGTCGAGCAAGCCGCCGGCGACCATCGAGTGGGAGTGA

Protein sequence :
MAHQDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMSNEEIRAFAPRGIILAGGPESVHEADSPRAPQAVFDLG
VPLFGICYGMQTMAEQLGGKVQGSDLREFGYARVDVVGKARLLDGIEDHVDDDGVLGLDVWMSHGDKVTGIPEGFHVLAS
TPSCPIAAMADDKRRYYGVQFHPEVTHTKQGLRILGRFVREICGCEALWTPSNIVEDAIAQVRAQVGGANVLLGLSGGVD
SSVVAALLHRAIGDRLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRADAEAQFLANLAGVSDPEQKRKIIGRTFIEVF
DAEAAKLENIRFLAQGTIYPDVIESAGARTGKAHVIKSHHNVGGLPEDMNLKLVEPLRELFKDEVRKIGLELGLPYDMVY
RHPFPGPGLGVRILGEVKKEYADLLRRADHIFIEELRKADWYHKVSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVD
FMTARWAHLPYELLEKVSNRIINEIDGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-132 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-131 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-132 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-118 50