Gene Information

Name : lktD (MHH_c06870)
Accession : YP_007882513.1
Strain : Mannheimia haemolytica M42548
Genome accession: NC_021082
Putative virulence/resistance : Virulence
Product : leukotoxin secretion protein LktD
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 639571 - 641007 bp
Length : 1437 bp
Strand : -
Note : -

DNA sequence :
ATGAAAATATGGCTTAGTGGTATTTATGAATTTTTCCTACGCTATAAAAACATTTGGGCAGAAGTATGGAAAATTCGTAA
AGAATTAGACCACCCAAACAGAAAAAAAGACGAAAGTGAATTTTTACCGGCACATTTAGAACTGATTGAAACCCCGGTTT
CTAAAAAACCACGTCTAATTGCTTATTTGATTATGCTATTTTTAGTTGTGGCAATTGTGCTTGCCAGTGTAAGCAAAGTT
GAAATTGTGGCGACTGCTCCCGGTAAATTAACTTTTAGTGGCAGAAGTAAAGAAATTAAACCGATTGAAAACGCCATTGT
ACAAGAAATTTTCGTTAAAGATGGGCAGTTTGTGGAAAAAGGGCAATTATTAGTCAGCTTAACTGCATTGGGTTCTGATG
CAGATATCAAAAAGACCATGGCTTCACTTTCTTTAGCTAAACTGGAGAACTATCGCTACCAAACTTTGCTTACTGCCATT
GAAAAAGAGTCCTTGCCGGTGATTGATTTATCTAGAACCGAATTTAAAGATTCATCGGAAGAAGATCGACTACGTATTAA
ACACTTAATTGAGGAGCAATACACCACTTGGCAAAAACAAAAAACACAGAAAACTTTAGCGTATAAGCGTAAAGAGGCTG
AAAAACAAACAATATTTGCCTATGTCCGTAAATATGAAGGTGCAACACGTATTGAACAAGAAAAATTAAAAGACTTTAAG
GCACTTTATAAACAGAAGTCTTTATCTAAGCACGAACTTCTTGCGCAAGAAAATAAATTAATTGAGGCTCAGAATGAGCT
AGCTGTTTATCGCTCAAAATTAAATGAATTAGAAAATGATCTACTCAATGTAAAAGAAGAACTTGAATTGATCACGCAAT
TCTTTAAAAGCGATGTGTTGGAAAAATTAAAGCAACATATTGAAAATGAACGCCAACTTCGGCTCGAGTTAGAAAAAAAT
AATCAACGCAGACAGGCCTCGATGATCAGAGCACCGGTTTCCGGTACGGTTCAGCAACTGAAAATTCACACTATAGGTGG
TGTTGTTACGACTGCTGAAACCTTGATGATCATTGTGCCGGAAGACGATGTGTTAGAGGCCACCGCTCTGGTTCCAAACA
AAGATATCGGCTTTGTTGCAGCAGGGCAGGAGGTGATTATTAAAGTGGAAACTTTCCCTTATACACGCTATGGTTATCTA
ACTGGTCGAATTAAACATATTAGCCCGGATGCGATTGAACAACCTAATGTAGGCTTAGTTTTTAATGCAACTATAGCTAT
AGATAGGAAGAATCTAACATCGCCTGATGGGCGAAAAATTGATTTGAGTTCAGGTATGACAATAACTGCTGAAATCAAAA
CCGGTGAACGGAGTGTAATGAGTTATTTACTCAGCCCATTAGAAGAATCTGTCACAGAAAGTTTAAGGGAACGCTAA

Protein sequence :
MKIWLSGIYEFFLRYKNIWAEVWKIRKELDHPNRKKDESEFLPAHLELIETPVSKKPRLIAYLIMLFLVVAIVLASVSKV
EIVATAPGKLTFSGRSKEIKPIENAIVQEIFVKDGQFVEKGQLLVSLTALGSDADIKKTMASLSLAKLENYRYQTLLTAI
EKESLPVIDLSRTEFKDSSEEDRLRIKHLIEEQYTTWQKQKTQKTLAYKRKEAEKQTIFAYVRKYEGATRIEQEKLKDFK
ALYKQKSLSKHELLAQENKLIEAQNELAVYRSKLNELENDLLNVKEELELITQFFKSDVLEKLKQHIENERQLRLELEKN
NQRRQASMIRAPVSGTVQQLKIHTIGGVVTTAETLMIIVPEDDVLEATALVPNKDIGFVAAGQEVIIKVETFPYTRYGYL
TGRIKHISPDAIEQPNVGLVFNATIAIDRKNLTSPDGRKIDLSSGMTITAEIKTGERSVMSYLLSPLEESVTESLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 2e-135 60
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 1e-119 60
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 5e-135 60
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 3e-135 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lktD YP_007882513.1 leukotoxin secretion protein LktD VFG1556 Protein 2e-135 60
lktD YP_007882513.1 leukotoxin secretion protein LktD VFG1502 Protein 3e-135 60
lktD YP_007882513.1 leukotoxin secretion protein LktD VFG0908 Protein 8e-136 60
lktD YP_007882513.1 leukotoxin secretion protein LktD VFG0843 Protein 3e-108 51