Gene Information

Name : MHH_c24310 (MHH_c24310)
Accession : YP_007884225.1
Strain : Mannheimia haemolytica M42548
Genome accession: NC_021082
Putative virulence/resistance : Unknown
Product : type I restriction enzyme, R subunit
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.21.3
Position : 2305634 - 2308792 bp
Length : 3159 bp
Strand : +
Note : hindVIIP

DNA sequence :
ATGATTACCATCAACGAAAACACCATTGAACAATCCGCCATTGCAACTTTGCAAAGCTTGGGCTGGGACTACACCTACGG
CAAAAAAATTTTGGCAGGTTTAGAACACGAATGGCGGGAGCGAACCGCTGAGGTGATTTTAAAGCCGCTTTTGGCGCAAG
CGATTGCAAAATTCAACCCGAATTTGCCCGCTTGTGAGGTGGAAAATGTGGTGGCACAGGTGTGCCGTGCCGACAGTGGC
GATTTGGCGGAGCGTAATCGTCAGGCTTATGATTGGCTAAGAAATGGGGTCAAAATCACTTATCAGTTGTACGGTGAGCA
GGTGTCTGATGTGGTGCAGCTGATTGATTTTCAGCGTCCAGAAAATAACGATTTTCGCATTGTCAATCAGCTGGATATTA
GCGGCAAAAAAGGCAAACGCATTCCGGATTTGATTGGCTTTGTTAATGGCTTGCCGCTGGTGGTGTTTGAGCTGAAAAAT
CCGCTCAAAGAAAATGCCGACATTGGCAAGGCGTTTGCCCAACTGCAAACCTATAAAGATGAAATTTCTGATTTGTTTGT
GTTTAATCAGGCACTCGTGATTTCAGACGGCATTGTCGCCCGCATCGGTTCGCTGACCGCTGATTTCGACCGTTTTACCC
CTTGGCGTGTGGTTGATGAAAAAAATCAGAGCAAACGCATTGTGTTTGAAGATGAACTCACCGCCCTGCTGCAAGGCGTG
ATGACACCCAAAAATCTCTTGGATTATGTGCAGAATTTTGTGGTGTTTGAACGGGACGGCAAAAACCGCTTAATTAAGAA
AATCGGAGCATATCATCAGTTTTATGGCGTGAATGAAGCGGTGGATTGCACCTTGCTTGCCGCCACAGGCAACCGCAAAA
TCGGCGTGTTTTGGCATACGCAAGGTTCGGGCAAATCGCTTTCGATGCTGTTTTATGCAGGTAAAGTATTAAGCCAAAGC
AGCCTGAAAAATCCAACTTTGGTGTTGGTAACCGACCGCAACGATTTGGACGGTCAGCTTTACGCCACTTTTTGCGGTGG
CGAGGCACTGCTCAAACAAACGCCAATCCAAGCCGATGGGCGAGACGAACTCCGCTCTGCCCTTGCCAGTCGTTCGGCAG
GCGGTGTGATTTTTACCACCATTCAAAAATTCGGCTTAATGGAGGGTGAGCTTGCCCACCCTGTATTAAACGAGCGGGAA
AACATCATTGTGATTACCGATGAAGCACACCGCTCACAATATGGTTTTAGCCAAAAAATCAACCACAAAGGCGAGTATCG
TGAGGGTTATGCCAAGCATTTACGCAGTGCATTGCCGAATGCCTCTTTTATTGGCTTTACTGGCACACCGATTGAACTTG
ATGACAAAGACACCCAAGAAGTCTTCGGTAAATATGTCTCGATTTATGATTTTGAAGATGCGGTGGAAGATGGGGCAACC
GTGCCGATTATTTATGAGCCACGCCAAATCAGCTTAGGCGAAAGTGGCGAGTTTTCCAAAGTGATGGAAGAGGCACAACA
ACTGATTGATGACGATGAAAACAGCTATAACTTCCGCCTGCGTGAAAAACTGCACAGCGTGGATAGCCGTTTGCAAAAAA
TGGCGGAAGATATTATTGCCCATTACGATGAGCGTACCAAACAGCAAGACGGCAAGGCGATGGTTGTGGTGATGAGCCGT
GCCATTTGCGTGAAATTGTACGAAAAAATCACCGCACTTCGTCCAGAATGGCACTCAAACGATGTGCTTCAAGGCAGCAT
TAAAATTGTGATGACAAGTAATGCCAGCGACCCTGCCGAGTGGCAAAAACACAATCAGGATAAGAAAACCTTAGAAAAAC
GCTTTAAAGACCCAGACGATCCGCTCAACATCGTGATTGTGCGGGATATGTGGCTGACAGGCTTTGATGCGCCCTGCTGT
AACACAATGTACATTGATAAACCAATGAGCGGACACAACCTGATGCAGGCAATCGCTCGGGTAAATCGGGTATTTCGCAA
CAAAAGCCGTGAAAATGGCGGCTTGATTGTGGATTATGTGGGCTTGACCGATGAGCTGGAAAAAGCGATGAAGCAGTACA
CCAACGCAGGCGGTAAAGAAAAGCCGGTGCGGGACATTTCAGCGGTGCTGGAAAAAATGGTGGAACATATCACGGTCATT
CATGGGCAATTTGCCACACCGATTGACGGACAAGCGGTTGATATTGCCAAAATGTTGCAAATCAGCGAACCGCCTAAACT
GCTCAATGCGATTTTGACATCAGCCAACCATATTCTTGCCCTAGACCGCATTCAGCCACCTGATAACACTGCCAAAGACA
AAACCCCACGCAAAAACGCCTTTTTGCAATCGGTACGCTTGGCGAAAAAAGGTTATGCTTTGTGTGGGGCATTAAAAGCA
GTTGAACCCTATAAACAGGAACTGGCGTTTTATGATGCAGTGCGTGCCACCATTATCAAAAACAGCACCGCTCCTCGCAA
TTCTTCGAGCGAAAATGACCGCTTGTTGCAGCTTACCGCCTTGATGAATCGTGCGGTACAGTCGGATGGTGTGGTGGATT
TATTTGATTTGCTGAAAAAAGACCGCCCAAACATCAACCTGCTTTCTGATGAGTTTTTGGAAACAGTAAAAAACAGCCCA
ACCAAAGATTTGTGGCTATCAGCAATGGAGCGTTATCTTGCCTCACAACTGCGAGAGCAAAGCGGTGCCAATCTTGCCAC
AAAAAAAGCATTTGAACAGAAACTCAAAGAGGCGATGAACCAATACCACAACCACAATTTAAGCGTATTGGAAATTTTAG
AAGAGCTGATCGCCCTCGCCAAAGAGTTTGAAGCCCGCCAAAAACGAGGGGAAGCGTTGGGACTAAGCCCTGCGGAAATG
GCGTTTTATGATGCTTTGGCACGTAATGAAAGTGCGGTGCGGGAAATGGGCGATGAGGTATTGATGAAACTTGCCAAAGA
CATTACCGATAAATTACGCAAATCGGTCACCGTAGATTGGCAATATAAAGACTCGGTTCGTGCCAAAATGCGAACCTTAA
TCCGCATTGCTCTGCGTACCTATAAATACCCGCCCGATTTACAGGCGGAAGCGATTGAGTTTGTGTTGCAACAAGCGGAA
GAGATCGCCGGAGAGTTCGCTATCACCGAAACGGCGTAA

Protein sequence :
MITINENTIEQSAIATLQSLGWDYTYGKKILAGLEHEWRERTAEVILKPLLAQAIAKFNPNLPACEVENVVAQVCRADSG
DLAERNRQAYDWLRNGVKITYQLYGEQVSDVVQLIDFQRPENNDFRIVNQLDISGKKGKRIPDLIGFVNGLPLVVFELKN
PLKENADIGKAFAQLQTYKDEISDLFVFNQALVISDGIVARIGSLTADFDRFTPWRVVDEKNQSKRIVFEDELTALLQGV
MTPKNLLDYVQNFVVFERDGKNRLIKKIGAYHQFYGVNEAVDCTLLAATGNRKIGVFWHTQGSGKSLSMLFYAGKVLSQS
SLKNPTLVLVTDRNDLDGQLYATFCGGEALLKQTPIQADGRDELRSALASRSAGGVIFTTIQKFGLMEGELAHPVLNERE
NIIVITDEAHRSQYGFSQKINHKGEYREGYAKHLRSALPNASFIGFTGTPIELDDKDTQEVFGKYVSIYDFEDAVEDGAT
VPIIYEPRQISLGESGEFSKVMEEAQQLIDDDENSYNFRLREKLHSVDSRLQKMAEDIIAHYDERTKQQDGKAMVVVMSR
AICVKLYEKITALRPEWHSNDVLQGSIKIVMTSNASDPAEWQKHNQDKKTLEKRFKDPDDPLNIVIVRDMWLTGFDAPCC
NTMYIDKPMSGHNLMQAIARVNRVFRNKSRENGGLIVDYVGLTDELEKAMKQYTNAGGKEKPVRDISAVLEKMVEHITVI
HGQFATPIDGQAVDIAKMLQISEPPKLLNAILTSANHILALDRIQPPDNTAKDKTPRKNAFLQSVRLAKKGYALCGALKA
VEPYKQELAFYDAVRATIIKNSTAPRNSSSENDRLLQLTALMNRAVQSDGVVDLFDLLKKDRPNINLLSDEFLETVKNSP
TKDLWLSAMERYLASQLREQSGANLATKKAFEQKLKEAMNQYHNHNLSVLEILEELIALAKEFEARQKRGEALGLSPAEM
AFYDALARNESAVREMGDEVLMKLAKDITDKLRKSVTVDWQYKDSVRAKMRTLIRIALRTYKYPPDLQAEAIEFVLQQAE
EIAGEFAITETA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 48
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 42
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 41
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 41