Gene Information

Name : topB2 (MHH_c23670)
Accession : YP_007884162.1
Strain : Mannheimia haemolytica M42548
Genome accession: NC_021082
Putative virulence/resistance : Unknown
Product : DNA topoisomerase 3 TopB
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 2226470 - 2228389 bp
Length : 1920 bp
Strand : +
Note : -

DNA sequence :
ATGCGTTTATTTGTTGCCGAAAAACCCAGCCTTGCCCGAGCGATTGCCGATGTGTTACCAAAACCCCATACCAAAGGAGA
TGGCTTTATCCAATGCGGCGAACACGACACTGTTACTTGGTGTATCGGTCATTTATTGGAACAGGCTGAACCCGATGTCT
ATGATGAGCGTTTCAAAATGTGGCGAATGGAACATTTGCCGATTGTGCCTGAACAATGGAAATTGATTCCCAAAAAAGAG
ACGCTCAAGCAGTTTAAAGTGGTGGAAAAGCTGATTAAAAAAGCCGATGTTTTAGTCAATGCCGGAGACCCGGATCGAGA
AGGGCAGCTGTTGGTGGACGAAGTTTTTGGCTATTTGAATTTATCTGCTGAACGCAAAAGCCAAATTCAGCGTTGTTTGG
TAAGCGATCTCAACCCGAATGCGGTGAGCCGAGCCATTGAAAAATTGCAAAAAAACAGCGATTTTATACCGCTTGCAACC
TCTGCTCTCGCCCGAGCCAGAGCGGATTGGCTGTATGGTATCAATATGACCCGAGCCTATACCCTACAGGGGCGTTGGGC
AGGCTATAAAGGCGTGTTATCAGTCGGACGTGTGCAAACGCCGGTATTAGGGCTGATTGTTCGCCGAGATCTGGAGATCG
AGCATTTCGTGCCAAAGGATTATTTTGAGGTGTTGGCACAGATTGTCGTGCCGGAAACCCAAGAGCGATTTAAGGCGCAG
TGGCAACCGAGCAAAGCCTGTGAAGATTATCAAGATGAAGATGGGCGGGTGCTGTCTCGTCCATTGGCAGAAAATGTGGT
AAAACGGATTACCGACCAGCCGGCAACCGTCACCGAATATCAAAATAAAATTGAAAAAGAAACTGCACCGCTGCCTTATT
CTCTTTCGGTATTACAAATGGAAGCCGCCGGCAGATATGGGCTATCCGCCCAAGCGGTGTTGGATATTTGCCAAAAGCTG
TATGAAACCCATAAACTAATTACCTACCCTCGTTCTGATAATCGGTATTTGCCGACCGAACATTTCAACGACAGATTTAA
AGTGATGGCGGCGATTGCTCATCATTTACCTGAATATCAACAAAAACCGGAAGTGATTGATGCCACTATTCGCAATCGTT
GCTGGAATGATAAAGAGGTGGAAGCCCACCACGCCATTATTCCCACTGCACGGCAAGGGACGGTACATTTAACCGAAAAT
GAAAAAAGAGTTTATCAACTCATTGCCCGCCAATATCTAATGCAATTCTGCCCTGATGCGGAATATCGCAAAAGTAAAAT
CGGGCTTGAAATTGCAGGTGGTAGTTTTGTCGCTCAAGCACGCAACCTTGTAATTGCCGGCTGGCGAGCGTTACTGGGTA
AAGAAGATAGCCTTGACGATGCAGAGCCACTACTACCGATTGTCAAAAAAGGGCAAATCCTCCATTGTGAAAAAGGGGAA
ATTGTCAGCAAAAAAACACAACCGCCCCGCCACTTTACTGATCGCAGTTTGCTTTCAGCAATGACCGGGATCGCCCGTTT
TGTACAAGATAAAGAATTGAAAAAAATCTTGCGTGAAACCGATGGTTTAGGCACGGAGGCAACCCGAGCCGGTATTATCG
AATTGCTGTTTAAACGTGGTTTTTTAATCCGTAAAGGGAAAAATATCCACAGTACCGAAGCCGGCAGAATATTGATTCAA
GCACTTCCCGACTCTGCTACCCAGCCGGATATGACCGCTCATTGGGAAATGCAGCTGAATCAAATCAGCAAAAAAGAGAC
CAGCTATCAGCAATTTATGTTTGATCTAAACCAACAGCTCCCACATTTATTACAAAGCCCAAACCGCCAAGTGTTGCAAA
ATTTAGCGAAAATCACACCGCTTGCAAGCGGCAATAAACCTCGTTATTTTAAAAAGCGAACACAAACTGCTGAAAATTAA

Protein sequence :
MRLFVAEKPSLARAIADVLPKPHTKGDGFIQCGEHDTVTWCIGHLLEQAEPDVYDERFKMWRMEHLPIVPEQWKLIPKKE
TLKQFKVVEKLIKKADVLVNAGDPDREGQLLVDEVFGYLNLSAERKSQIQRCLVSDLNPNAVSRAIEKLQKNSDFIPLAT
SALARARADWLYGINMTRAYTLQGRWAGYKGVLSVGRVQTPVLGLIVRRDLEIEHFVPKDYFEVLAQIVVPETQERFKAQ
WQPSKACEDYQDEDGRVLSRPLAENVVKRITDQPATVTEYQNKIEKETAPLPYSLSVLQMEAAGRYGLSAQAVLDICQKL
YETHKLITYPRSDNRYLPTEHFNDRFKVMAAIAHHLPEYQQKPEVIDATIRNRCWNDKEVEAHHAIIPTARQGTVHLTEN
EKRVYQLIARQYLMQFCPDAEYRKSKIGLEIAGGSFVAQARNLVIAGWRALLGKEDSLDDAEPLLPIVKKGQILHCEKGE
IVSKKTQPPRHFTDRSLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLIRKGKNIHSTEAGRILIQ
ALPDSATQPDMTAHWEMQLNQISKKETSYQQFMFDLNQQLPHLLQSPNRQVLQNLAKITPLASGNKPRYFKKRTQTAEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-109 42
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-109 42
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-109 42
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 6e-107 42