Gene Information

Name : tetH (MHH_c23160)
Accession : YP_007884113.1
Strain : Mannheimia haemolytica M42548
Genome accession: NC_021082
Putative virulence/resistance : Resistance
Product : tetracycline efflux protein, class H
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2178983 - 2180185 bp
Length : 1203 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAATCAATTATTATTATACTGCTGATCACCGTATTAGATGCCATTGGTATCGGGCTTATCATGCCAGTACTCCC
TACTCTATTAAATGAATTTGTCAGTGAAAATTCACTGGCAACCCATTACGGTGTGCTATTAGCGCTCTATGCTACCATGC
AGGTTATTTTTGCTCCTATTCTAGGACGACTGTCTGATAAATACGGCAGAAAACCCATCTTGCTGTTTTCCCTTTTAGGC
GCGGCACTCGACTATCTTTTAATGGCATTCTCAACCACACTTTGGATGCTCTATATTGGGCGCATCATTGCGGGGATCAC
AGGCGCAACAGGTGCCGTATGTGCATCAGCGATGAGTGATGTGACTCCCGCTAAAAATCGAACTCGCTATTTTGGTTTCT
TAGGTGGTGCTTTTGGTGTTGGCCTTATTATCGGCCCAATGCTAGGGGGATTATTAGGTGATATCAGTGCTCATATGCCA
TTTATTTTTGCCGCTATTTCACACTCGATATTATTAATACTCTCTTTGCTCTTTTTCCGAGAAACACAAAAAAGAGAAGC
GCTTGTTGCCAATAGGACACCTGAAAACCAAACTGCCTCAAATACAGTCACTGTTTTTTTTAAGAAAAGCCTCTACTTTT
GGTTAGCAACCTATTTTATTATCCAGCTTATCGGGCAAATTCCTGCCACCATCTGGGTGCTGTTTACACAATATCGTTTT
GATTGGAACACAACTTCTATCGGTATGTCTTTGGCGGTTCTGGGTGTATTACATATTTTCTTTCAGGCGATTGTCGCTGG
GAAATTGGCACAAAAATGGGGCGAAAAAACCACCATTATGATCAGTATGTCTATTGATATGATGGGCTGTTTATTATTAG
CGTGGATAGGCCACGTTTGGGTCATCTTACCAGCATTAATTTGCTTAGCGGCAGGAGGTATGGGGCAACCCGCATTACAA
GGTTATTTATCAAAATCTGTCGATGATAATGCGCAAGGGAAATTACAAGGTACTCTGGTGAGCCTAACCAATATTACCGG
GATCATTGGTCCCCTTTTATTTGCCTTTATTTATAGTTATAGCGTCGCTTATTGGGATGGTCTGTTATGGCTGATGGGGG
CAATACTTTATGCTATGTTGCTTATTACCGCTTATTTTCACCAAAGAAAAACCACACCTAAAGCTGTTATTTCAACCCCT
TAA

Protein sequence :
MNKSIIIILLITVLDAIGIGLIMPVLPTLLNEFVSENSLATHYGVLLALYATMQVIFAPILGRLSDKYGRKPILLFSLLG
AALDYLLMAFSTTLWMLYIGRIIAGITGATGAVCASAMSDVTPAKNRTRYFGFLGGAFGVGLIIGPMLGGLLGDISAHMP
FIFAAISHSILLILSLLFFRETQKREALVANRTPENQTASNTVTVFFKKSLYFWLATYFIIQLIGQIPATIWVLFTQYRF
DWNTTSIGMSLAVLGVLHIFFQAIVAGKLAQKWGEKTTIMISMSIDMMGCLLLAWIGHVWVILPALICLAAGGMGQPALQ
GYLSKSVDDNAQGKLQGTLVSLTNITGIIGPLLFAFIYSYSVAYWDGLLWLMGAILYAMLLITAYFHQRKTTPKAVISTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 2e-144 99
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 3e-71 54
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 4e-71 54
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 3e-71 54
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 4e-71 54
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 4e-71 54
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 4e-71 54
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 1e-69 54
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 4e-71 54
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 3e-71 54
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 4e-62 50
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 3e-58 50
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 3e-58 50
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 3e-58 50
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 3e-58 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetH YP_007884113.1 tetracycline efflux protein, class H Y15510.gene.p01 Protein 3e-145 100
tetH YP_007884113.1 tetracycline efflux protein, class H AF038993.gene.p01 Protein 2e-119 80
tetH YP_007884113.1 tetracycline efflux protein, class H CP004022.1.gene2534. Protein 3e-120 80
tetH YP_007884113.1 tetracycline efflux protein, class H AJ250203.gene.p01 Protein 3e-72 55
tetH YP_007884113.1 tetracycline efflux protein, class H V00611.gene.p01 Protein 5e-71 54
tetH YP_007884113.1 tetracycline efflux protein, class H AB084246.gene.p01 Protein 1e-71 54
tetH YP_007884113.1 tetracycline efflux protein, class H NC_010558.1.6275971. Protein 2e-71 54
tetH YP_007884113.1 tetracycline efflux protein, class H L06798.gene.p01 Protein 3e-68 53
tetH YP_007884113.1 tetracycline efflux protein, class H AF133139.gene.p01 Protein 1e-60 50
tetH YP_007884113.1 tetracycline efflux protein, class H NC_010410.6002612.p0 Protein 2e-62 50
tetH YP_007884113.1 tetracycline efflux protein, class H AF133140.gene.p01 Protein 2e-62 50
tetH YP_007884113.1 tetracycline efflux protein, class H L06940.gene.p01 Protein 4e-62 50
tetH YP_007884113.1 tetracycline efflux protein, class H Y19114.gene.p01 Protein 3e-62 49
tetH YP_007884113.1 tetracycline efflux protein, class H AF070999.gene.p01 Protein 3e-57 49
tetH YP_007884113.1 tetracycline efflux protein, class H Y19116.gene.p01 Protein 4e-60 49
tetH YP_007884113.1 tetracycline efflux protein, class H AY264780.2.gene3.p01 Protein 2e-48 43
tetH YP_007884113.1 tetracycline efflux protein, class H AY743590.gene.p01 Protein 4e-44 43
tetH YP_007884113.1 tetracycline efflux protein, class H AF121000.gene.p01 Protein 8e-53 42
tetH YP_007884113.1 tetracycline efflux protein, class H AJ420072.gene.p01 Protein 1e-50 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetH YP_007884113.1 tetracycline efflux protein, class H VFG1036 Protein 2e-71 54