Gene Information

Name : topB1 (MHH_c23040)
Accession : YP_007884101.1
Strain : Mannheimia haemolytica M42548
Genome accession: NC_021082
Putative virulence/resistance : Unknown
Product : DNA topoisomerase 3 TopB
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 2169447 - 2171498 bp
Length : 2052 bp
Strand : -
Note : -

DNA sequence :
ATGAAATTATTTATTTGTGAAAAGCCATCTCAAGCTCGAGATCTTGCCGGCGTATTGGGTGCTACTTCAAAAGGTGAAGG
CTTGCTGGCGACTGCGGATAAATCTATTATTGTCACTTGGGGGTTCGGGCATCTCGTTGAGCAATATCAGCCGGAAGATT
ATGATGAAGCGTGGAAACGCTGGGCATTTGAAACATTACCCATTATTCCTGCTCAGTGGAAAATGACACCGAAAAAAGAG
TCTAAGAAGCAATATTCTGTTGTAATAGGGCTTATCAAAAAAGCAACCTCCGTGGTCATTGCGACCGATGCTGATCGAGA
AGGTGAGATGATTGCTCGTGAGCTGTTAGATTTAGCTGGATACCGAGGTCAAATCCAACGTTGCTGGCTATCAGCTCTGG
ATGATGCCAGTATTCGAAAGGCTCTTCAAACACTCAAATCAGGTAAAGAAACCGAGGCTCTTTACTACGCCGGTATGGGA
CGTAGCCGCTCGGACTGGTTGATTGGAATGAACTTCTCCCGTTTATTTACCTTAATGGCTCAAGCAAAAGGCTATTCCGG
TAAGCCATTGAGCGTTGGTCGAGTACAAAGTCCAACATTAACTCTTGTGGTTAATCGAGATAGAGAAATTGCTAATTTCG
TGCCTAAATCTCATTATGCGTTAGCGGTTCAGCTGACAACAACCTCTGGTGAAACTTTCGTTGCCGGGCTTGCAGTACCT
GAACAGTATTTGGATGAGTCCGGACTTTGCCTTGATAGTCGTGTCATACAACAAGCCGAAGCTCAAATTAAACAAACAGG
CTTAGCCAAAGTGGTGACGGTTGAAACTAAACGAGAGAAAAAATCTCCACCGTTACTCTACGCATTAAGTGATTTACAAG
GCGAATGTAACCGCTTGTTTGGCTTTGGGGCTCAGCAGGTGTTGGATATCGCACAATCCCTTTACGAAGAGCATAAAATC
ACGACTTATCCCCGTACAGACTGTGGTTATCTGCCAGAATCACAATTTTCTGATGTTCCTAACGTAATCCGCTCATTAGT
TGCCTCTGATTCAGGGCTACAAACTCTCTTGCCTAAATTAAATTTGCGACAAAAAAGTCGGGCGTGGGACGATAAAAAAA
TTACCGCTCACCACGGTATTATCCCAACCATTAAAAAAGCTGATTTAAGTAAATTGAGTGAGGAGGAAATGAAGGTCTAT
GATCTCATTCGCCGCCGATATCTTGCTCAATTCTTACCGCACTTGGAAATGGATAAAACCGTTGCCACTCTGCAATCTAG
TGGGCACACTCTGGTTGCTCGGGGAAATGTCATCGTTGCTCAAGGCTGGCGTATCTTGTTTGGCAAAAATGTGGATGAGG
AAACTGGTAATGATGATGAGAAACAAGGATTACCTGTATTGACTAAAAATCAGCAATGCAATGTCACTCATTCTGAAGTC
CGAACATTGCAAACTAAACCTCCCGCACACTATACAGAGGGGACATTACTCGATGCAATGAAAAATGCCGCTCGCTTTGT
GACTGACCCAAGACTCAAACAACGCTTACGTGAAACGGAAGGTTTAGGCACAGAAGCAACCCGTGCCGGATTAATTCAAG
GCCTAATTGACAAAGGATTTCTCCTTAAGAAGAAAAAATCACTGGTTGCCTCAGCAGAAGCCGTTGCCTTAATTGATAGT
TTGCCGGACTTACTGAAAAATCCCGGTTTAACGGCATTATGGGAACAAGCCCTCAATCAGATTGCCGAAGGTAGTATGAC
ACTTGATGCATTTATGCAAAAGCAAGAAGCATTTGTAAAACAACTTATCGGCAGTTGTATGCAACAGGGAATGTCACTTG
GGAATATTGAAATCCGAAAATGTTCAGAATGTGGTAAGCCAATGAGAAAAATCAATCACGCTAAGGGAACATTCTGGGGA
TGTACTGGTTATCCAGATTGCCAACATAAAGAGGCTGATAAAAAGGTAAAATCAGCTTCAAATAAATCTGCTAAGAAAAG
TAGTAATTTAAATGTACTCGATCAACTGAATAAATTAAGAAGCCAGTTATAA

Protein sequence :
MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKRWAFETLPIIPAQWKMTPKKE
SKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAGYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMG
RSRSDWLIGMNFSRLFTLMAQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP
EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLFGFGAQQVLDIAQSLYEEHKI
TTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKLNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVY
DLIRRRYLAQFLPHLEMDKTVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV
RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGFLLKKKKSLVASAEAVALIDS
LPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWG
CTGYPDCQHKEADKKVKSASNKSAKKSSNLNVLDQLNKLRSQL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 0.0 100
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-155 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-149 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-149 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 9e-150 50
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 3e-157 50
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 7e-151 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 1e-139 47