Gene Information

Name : aphA1 (MHH_c22550)
Accession : YP_007884052.1
Strain : Mannheimia haemolytica M42548
Genome accession: NC_021082
Putative virulence/resistance : Resistance
Product : aminoglycoside 3'-phosphotransferase protein AphA
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.95
Position : 2128248 - 2129063 bp
Length : 816 bp
Strand : -
Note : -

DNA sequence :
ATGAGCCATATTCAACGGGAAACGTCTTGCTCGAGGCCGCGATTAAATTCCAACCTGGATGCTGATTTATATGGGTATAA
ATGGGCTCGCGATAATGTCGGGCAATCAGGTGCGACAATCTATCGATTGTATGGGAAGCCCGATGCGCCAGAGTTGTTTC
TGAAACATGGCAAAGGTAGCGTTGCCAATGATGTTACAGATGAGATGGTCAGACTAAACTGGCTGACGGCATTTATGCCT
CTTCCGACCATCAAGCATTTTATCCGTACTCCTGATGATGCATGGTTACTCACCACTGCGCTCCCCGGGAAAACAGCATT
CCAGGTATTAGAAGAATATCCTGATTCAGGTGAAAATATTGTTGATGCGCTGGCAGCGTTCCTGCGCCGGTTGCATTCGA
TTCCTGTTAGTAATTGTCCTTTTAACAGCGATCGCGTATTTCGTCTCGCTCAGGCGCAATCACGAATGAATAACGGTTTG
GTTGATGCGAGTGATTTTGATGACGAGCGTAATGGCTGGCCTGTTGAACAAGTCTGGAAAGAAATGCATAAGCTTTTGCC
ATTCTCACCGGATTCAGTCGTCACTCATGGTGATTTCTCACTTGATAACCTTATTTTTGACGAGGGGAAATTAATAGGTT
GTATTGATGTTGGACGAGTCGGAATCGCAGACCGATACCAGGATCTTGCCATCCTATGGAACTGCCTCGGTGAATTTTCT
CCTTCATTACAGAAACGGCTTTTTCAAAAATATGGTATTGATAATCCTGATATGAATAAATTGCAGTTTCATTTGATGCT
CGATGAGTTTTTCTGA

Protein sequence :
MSHIQRETSCSRPRLNSNLDADLYGYKWARDNVGQSGATIYRLYGKPDAPELFLKHGKGSVANDVTDEMVRLNWLTAFMP
LPTIKHFIRTPDDAWLLTTALPGKTAFQVLEEYPDSGENIVDALAAFLRRLHSIPVSNCPFNSDRVFRLAQAQSRMNNGL
VDASDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVGRVGIADRYQDLAILWNCLGEFS
PSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aphA1 YP_005176178.1 aminoglycoside 3'-phosphotransferase protein Not tested ICEPmu1 Protein 4e-126 100
aphA1 ADZ05811.1 aminoglycoside (3')-phosphotransferase APH (3')-Ia Not tested AbaR20 Protein 5e-94 99
aphA1a AGK07038.1 AphA1a Not tested SGI1 Protein 8e-125 99
aphA1a AGK07096.1 AphA1a aminoglycoside phosphotransferase Not tested SGI1 Protein 8e-125 99
aphA1 CAJ77079.1 Aminoglycoside phosphotransferase Not tested AbaR1 Protein 7e-125 99
aphA1b YP_005797124.1 aminoglycoside 3'-phosphotransferase aphA1 Not tested AbaR4e Protein 1e-124 99
aphA1b AFV53106.1 aminoglycoside (3') phosphotransferase AphA1 or APH (3')-Ia Not tested AbGRI2-1 Protein 7e-125 99
aphA1b YP_005797139.1 aminoglycoside 3'-phosphotransferase aphA1 Not tested AbaR4e Protein 1e-124 99
apha1b AGK36640.1 aminoglycoside (3') phosphotransferase AphA1b or APH(3')-Ia Not tested AbaR26 Protein 7e-125 99
aph(3')-Ia YP_001800929.1 aminoglycoside 3'-phosphotransferase Not tested Not named Protein 1e-124 99
aphA1b ACN81017.1 aminoglycoside (3') phosphotransferase AphA1 or APH (3')-Ia Not tested AbaR5 Protein 1e-124 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aphA1 YP_007884052.1 aminoglycoside 3'-phosphotransferase protein AphA V00359.1.orf1.gene.p Protein 5e-125 99