Gene Information

Name : guaA (K649_12875)
Accession : YP_007881358.1
Strain : Meiothermus ruber DSM 1279
Genome accession: NC_021081
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 2558409 - 2559935 bp
Length : 1527 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGAGCGTCGTTATCCTCGATTATGGCTCTCAGTACACCCGTTTGATCGCCCGGCGCATCCGTGAGCTACGGGCTTATTC
GGTTATTTTGCCGGGAACGGCTAGCCTGGAGCGCATTCAGGCCGAACGTCCGCAGGCCCTTATTCTTTCAGGGGGGCCAG
CCTCGGTGTTCGAACCCAACAGTCCGCGCCCCGCGCCAGGGGTGCTCGAGCAGGGCTGGCCCGTCCTGGGCATCTGTTAC
GGAATGCAGTACCTGGCCCAGTACTTTGGAGGCAGGGTTGAGCGGGCTGGGCGGCGCGAGTACGGCAAGGCCAACCTGGT
GCACCACACCGGCCCTTTATTTGCTGGCCTCGAGGGGGAGCTACAGATGTGGATGTCCCACTCCGATGCCGTTACCGAAC
TACCCCCAGGCTGGCAGGTGATTGCCAGCACCGAAGAGAACCCGGTGGCCGCTATTGCCGCGCCCGATGGCCGAACTTTT
GGGGTGCAGTTTCACCCCGAGGTGGTGCACAGCCCCAAAGGGATGCAGGTGCTGGAGAATTTCCTCGAGCTGGCGGGGGT
GGTCCGCGACTGGACGGCCCAGCACACCCTGGAGCACCTGATCGCCGATATCCGGGCGAAGGTTGGGGACGAAAAAGTGC
TGCTGGCTGTTTCAGGCGGGGTGGACTCATCGACCCTGGCCCTGCTTCTGGCTCGAGCCATTGGCGACCGGATGACCGCG
GTGTTTGTAGACCATGGCCTGCTGCGCCTGGGTGAGCGCCAGGAGGTCGAGCAGGCCCTGCGCCCCCTGGGGAAAGCCCT
GCGGGTTGTAGAGGCTTCCGGGCAGTTTCTCTCGGCCTTGCGAGGGGTGACCGATCCCGAACAGAAACGCAAGATTGTGG
GGCGCGAGTTTATCCGGGTCTTTGAGCGGGAAGCCCGGCAATTGTCGGCCCAGGGCTATAGATGGCTGGCCCAGGGCACC
CTGTACCCCGATGTAATCGAGTCAGCGGGTAGCGGCGAGGGCAGCGCCAACATCAAGAGCCACCACAACGTGGGGGGCCT
GCCCGAGGATTTGCAGTTTGAGCTGCTCGAGCCTTTCCGCTATCTGTTCAAAGACGAGGTGCGGGAGCTGGCCTTGCTGC
TGGGCTTGCCCGAGCCCATTCGGATGCGCCACCCTTTCCCCGGGCCAGGCCTGGCAATTCGCATACTGGGGGAGGTGACC
CCACAAAAACTGGAGATTCTACGCCGGGCCGACGACATTTTTATCTCCAGCCTGCGCGACTGGAACCTGTACGACCAGGT
CTCACAGGCGGCTGCCATCCTGACCCCTATGCAAAGCGTGGGGGTGGTGGGGGACGAACGGAGCTATGGCTATGTGCTGG
GTTTGCGGGCGGTCTCCACCGTGGACTTTATGACCGCCGACTGGGCCCGGCTTCCCCTGGAATTCTTAGATGAGGTGGCC
CGCAAAATCACCCGCCAGGTGCCGGAGATTGGGCGGGTGGTTTACGACATCACCAGCAAGCCACCGGCTACCATTGAGTG
GGAATGA

Protein sequence :
MSVVILDYGSQYTRLIARRIRELRAYSVILPGTASLERIQAERPQALILSGGPASVFEPNSPRPAPGVLEQGWPVLGICY
GMQYLAQYFGGRVERAGRREYGKANLVHHTGPLFAGLEGELQMWMSHSDAVTELPPGWQVIASTEENPVAAIAAPDGRTF
GVQFHPEVVHSPKGMQVLENFLELAGVVRDWTAQHTLEHLIADIRAKVGDEKVLLAVSGGVDSSTLALLLARAIGDRMTA
VFVDHGLLRLGERQEVEQALRPLGKALRVVEASGQFLSALRGVTDPEQKRKIVGREFIRVFEREARQLSAQGYRWLAQGT
LYPDVIESAGSGEGSANIKSHHNVGGLPEDLQFELLEPFRYLFKDEVRELALLLGLPEPIRMRHPFPGPGLAIRILGEVT
PQKLEILRRADDIFISSLRDWNLYDQVSQAAAILTPMQSVGVVGDERSYGYVLGLRAVSTVDFMTADWARLPLEFLDEVA
RKITRQVPEIGRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-109 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-109 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-109 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-117 51