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Name : K649_10280 (K649_10280) Accession : YP_007880845.1 Strain : Meiothermus ruber DSM 1279 Genome accession: NC_021081 Putative virulence/resistance : Unknown Product : type I site-specific deoxyribonuclease HsdR family protein Function : - COG functional category : - COG ID : - EC number : - Position : 2050768 - 2053896 bp Length : 3129 bp Strand : + Note : COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases DNA sequence : ATGGCGCAAATGACCGAATCTGTCGTTGAAGAAGCCGCCCTGGCCTGGCTCGAGGCCGCCGGTTGGCAGGTGGTACACGG CCCCGAGATTGCCCCCGACCAGCCCCAGGCCGAGCGGGCCGACTATGGTCAGGTGGTGCTCGAGCAGCGGCTGCGCGATG CGCTGGTGCGGCTTAACCCTGGGCTGCCTGCAGAGACGCTGGAGGACGCCTCCCGCAAGCTCACCCAGCCTGAGGGTTCA GACCTAATCCAACGAAACCGCGCCCTGCACCGCCTGCTGGTGAATGGCGTAAACGTGGAGTACCGCGACAAGGACGGCGA GATTCGCGGCGCACAGGCCAGAGTAATTGATTTTGACAACCCAGCCAACAACGACTGGCTGGCGGTCAATCAGTTCAGCG TTGTGGAGAGGGGTACGTTGCAACGTGCCCCATCTATGCAACGTGCCTCAACCCGCCGCCCCGACGTGGTGCTGTTCGTC AATGGCCTACCGCTGGCAGTAGTGGAGCTGAAGAACGCTGCCGACGAAGACGCGACAATCTGGACGGCGTGGCAGCAGCT CCAGACCTACCAGGCCGAAATCCCCTCGCTCTTTGTGCCCAACGCGGTGCTGGTGATTTCCGATGGGGTGGAGGCGCGCG TGGGGGTGGTGGGGGCAGGGCGGGAGTGGTTCAAGCCCTGGCGCACGGTGGCTGGCGATCGCCTGGCCGACAGCCACGTG CCCGAGTTGCAGGTGGTGCTCGAGGGGGTGTTCGCACCGCGGCGCTTCCTCGACCTGGTGCGCGACTTCATCGTGTTTGA GGATGACGGCAGCGGACGATTGATCAAGAAAATGGCGGGTTATCACCAGTTCCACGCGGTGCAGGTGGCAGTACAGGAAA CGCTGCGGGCGGCCCTGGCCTTGCGCGAGGGTAGGGGGGGCCAGTCGGGCGACCGGCGCATCGGCGTGGTCTGGCACACC CAGGGCTCGGGTAAAAGCCTGACCATGGCGTTTTACGCCGGGCGCATCATCCGCGAACCCGCCATGGAGAACCCCACCCT GGTGGTGCTCACCGACCGCAACGACCTCGACGACCAGCTTTACAGCACCTTTGCGCGTTGCCACGAGTTGCTGCGCCAGC CGCCGGTGCAGGCCGAAAGCCGCGCCCACCTGCGCGAGCTGCTCTCGGTGCAGTCGGGCGGGGTGGTCTTCACCACCATC CAGAAGTTCATGCCCGAAGAGAAAGGCGACCGCCACCCGCGGCTTTCCGAGCGGCGCAACATCGTGGTTATTGCCGACGA AGCCCATCGCAGCCAGTACGACTTCATAGATGGCTTTGCCCGCCATATGCGCGACGCCCTGCCCAACGCCTCTTTTATCG GCTTCACCGGAACCCCCATCGAGCTTCAGGATGCCAATACCCGCGCGGTGTTTGGCGATTACATCAGCATCTACGACATC CAGCGCGCCGTGGAGGACGGGGCCACCGTGCCCATCTATTACGAAAGCCGCCAGGCCAAGCTTGACCTGCCTGAGGAACT CAAGCCGAAGATTGATGAGGAATTCGAGGAAGTTACCGAGGGGGAGGAACTCGAGCGCAAGGAGAAGCTCAAGAGCAAGT GGGCGCAGCTCGAGGCCATCGTGGGTGCGGAAAGGCGGCTGCGCCTGGTGGCGAAGGATATTGTCCAGCACTTCGAACAG CGGCTCGAGGCCTTGGACGGCAAGGCCATGATTGTCTGCATGAGCCGTCGCATTTGCGTGGAACTCTACCGCGAGATTGT GCGCCTGAGGCCCCAGTGGCATCACGACGACGACGACAAAGGCGCGATCAAGATCGTGATGACCGGCTCCGCTTCCGACC CACCCGACTGGCAGCCGCACATCCGCAACAAGCCCCGCCGCGAAGCGCTGGCTAAGCGTTTCCGCGATCCCGAAGATGCC TTCAAGCTGGTCATTGTGCGCGACATGTGGCTTACCGGCTTCGACGCGCCCAGCCTGCACACCATGTACCTGGACAAGCC CATGCGTGGACACGGCCTGATGCAGGCCATCGCGCGGGTAAACCGGGTCTTCCGCGACAAGCCCGGCGGGCTGGTGGTGG ATTACCTGGGGCTGGCTACCGAGCTAAAAGCCGCGCTGGCTACCTACACCGAGAGCGGCGGCACCGGACGCACCGCGCTC AATCAGGAAGAAGCGGTGGCGCTCATGCGCGAGAAATACGAGATTTGCCGTGGCCTTTTTTACGGCTTCGACTGGTCGAG GTGGGTTACGGGCACGCCGGCGGAACGGCTGAGCCTTCTGCCTGCCGCGCAGGAGCACATCCTCGCTCAGGAGAACGGCA AGGATCGGCTGCTGCGTGCGGCGCGCGAGCTGTCACAAGCGTTCGCGCTGGCTGTGCCGCATGAAGAGGCCCTGCGCATC CGAGACGACGTGGCCTTCTTCCAGGCCGTGCAAGCGGTGCTGGCTAAACGCGCGCCAGGCCAGGCACGGCCCGAGGAGGA ACTCGAGCAGGCCGTGCGCCAGATAATCGCCCGTGCGGTGGCACCCGAGGGTGTGGTGGACATTTTCGCAGCAGCGGGGC TCAAGAGGCCGGACATCTCCATACTCTCCGATGAGTTTTTGTCCGAGGTGCGGGGGATGCCGCAGAAAAACCTGGCGGTA GAGCTATTGCAAAAGCTGCTTAAAGGAGAGATTCGGGCTCGAGGACAGAAGAACCTGGTGCAGGCCAGGTCGTTTGCCGA GATGCTCGAGCGAACCATCCGCCGTTACCAGAACCGGGCCATCGAGGCCGCCCAGGTGATTGAAGAACTCATCGCGCTCG CCAGGGATATGCGCGAAGCCAATGCCCGTGGCGAGAAACTCGGCTTATCCGAGGACGAACTGGCCTTCTACGATGCCCTC GAGGCCAACGACAGCGCGGTCAAGGTGCTGGGCGACGCAACCTTGCGGGAAATTGCCCGTGAACTGGTTCAGACGGTGCG CAACAATGTAACCCTCGACTGGACCTTGCGTGAGAATGTGCGGGCGCAGTTGCGCGTGCTGGTCAAACGCACGCTGCGCA AATACGGCTACCCACCCGACAAGCAGGAGAAAGCCACCCAGACGGTACTGGAGCAAGCTGCGCTACTGTCGGCGCAGTGG GCAGCCTAG Protein sequence : MAQMTESVVEEAALAWLEAAGWQVVHGPEIAPDQPQAERADYGQVVLEQRLRDALVRLNPGLPAETLEDASRKLTQPEGS DLIQRNRALHRLLVNGVNVEYRDKDGEIRGAQARVIDFDNPANNDWLAVNQFSVVERGTLQRAPSMQRASTRRPDVVLFV NGLPLAVVELKNAADEDATIWTAWQQLQTYQAEIPSLFVPNAVLVISDGVEARVGVVGAGREWFKPWRTVAGDRLADSHV PELQVVLEGVFAPRRFLDLVRDFIVFEDDGSGRLIKKMAGYHQFHAVQVAVQETLRAALALREGRGGQSGDRRIGVVWHT QGSGKSLTMAFYAGRIIREPAMENPTLVVLTDRNDLDDQLYSTFARCHELLRQPPVQAESRAHLRELLSVQSGGVVFTTI QKFMPEEKGDRHPRLSERRNIVVIADEAHRSQYDFIDGFARHMRDALPNASFIGFTGTPIELQDANTRAVFGDYISIYDI QRAVEDGATVPIYYESRQAKLDLPEELKPKIDEEFEEVTEGEELERKEKLKSKWAQLEAIVGAERRLRLVAKDIVQHFEQ RLEALDGKAMIVCMSRRICVELYREIVRLRPQWHHDDDDKGAIKIVMTGSASDPPDWQPHIRNKPRREALAKRFRDPEDA FKLVIVRDMWLTGFDAPSLHTMYLDKPMRGHGLMQAIARVNRVFRDKPGGLVVDYLGLATELKAALATYTESGGTGRTAL NQEEAVALMREKYEICRGLFYGFDWSRWVTGTPAERLSLLPAAQEHILAQENGKDRLLRAARELSQAFALAVPHEEALRI RDDVAFFQAVQAVLAKRAPGQARPEEELEQAVRQIIARAVAPEGVVDIFAAAGLKRPDISILSDEFLSEVRGMPQKNLAV ELLQKLLKGEIRARGQKNLVQARSFAEMLERTIRRYQNRAIEAAQVIEELIALARDMREANARGEKLGLSEDELAFYDAL EANDSAVKVLGDATLREIARELVQTVRNNVTLDWTLRENVRAQLRVLVKRTLRKYGYPPDKQEKATQTVLEQAALLSAQW AA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 50 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 47 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 47 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 47 |
