Gene Information

Name : pykA (MPC_442)
Accession : YP_007864444.1
Strain : Candidatus Moranella endobia PCVAL
Genome accession: NC_021057
Putative virulence/resistance : Virulence
Product : Pyruvate kinase II
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 493880 - 495322 bp
Length : 1443 bp
Strand : +
Note : -

DNA sequence : 
ATGTCCAGACAGCTAAGAAGAACAAAAATTGTCACTACTCTCGGTCCGGTAACCGATCGTGATAATAATCTTGAAAAAGT
AATAAACGCCGGAGCCAACGTTGTTCGCCTCAATTTTTCACACGGTAGCGCAGAAGAGCATATCCTAAGGGCACAAAAAG
TGCGCGATATTTCAGCCCGCCTCGGCCGACATATCGCGGTACTTGGTGATTTACAGGGGCCAAAAATACGCATTTCAACT
TTTAGGGACGGGAACATTGTCCTGAAAGTAAGCGACAAATTTTTACTAGATGCTTCATTAGGCCGCGGTGAAGGTGACTG
CGAACGTGTAGGCATTGACTATAAAGGTTTACCGGAAGATGTGGCGCCAGGCGATATACTGCTACTAGATGATGGCCGAG
TACAACTGAAAGTGCTCGAAGTTCAGGGTATCAGGGTTTATACCCAAGTCACGGTAGGTGGGCCGCTGTCCAACAATAAA
GGTATAAACAAGCTTGGAGGTGGTTTGTCTGCTGAAGCTCTGACTGAGAAAGACAAATCAGATATCATTACTGCAGCAAA
AATAGGTGTTGATTACCTGGCGATTTCATTTCCCCGCACTAGTGAAGATCTTAACTATGCGCGCCGGCTGGCGCGTGAGG
CCGGCAGCTATGCCAAAATTGTATCAAAAATAGAAAGAGCAGAAGCTGTGGCTACCGAGGAAGCCATGGACGAAATCATT
CTCGCTTCAGATGTGGTGATGGTGGCAAGGGGCGACTTAGGTGTGGAAATCGGCGATCCAGAATTAGTAGGTATTCAAAA
AACATTAATCCGCCGAGCCCGCACTCTTAACCGTGCCGTTATTACTGCTACGCAGATGATGGAATCAATGATTAATAACC
CGATGCCCACGCGCGCTGAAGTGATGGATGTTGCTAATGCGGTGCTAGACGGCACCGACGCGGTAATGCTGTCAGCCGAA
ACGGCAGCAGGGCGGTATCCAGCCGAAACAGTATCTACTATGGCAAGCGTTTGCCTTGGAGCGGAAAAAATTCCCAGTAT
TAATCTCTCCAAGCATCGGTTGGACGTGCAATTTGACAATATTGAAGAAGCCATAGCTATGGCTGCTATGTATGCTGCTA
ATCATCTTAAGGGTGTAACAGCAATTATCTCAATGACGGAATCTGGCAGCACCGCACTCATGATGTCCAGGATTAGTTCT
GGTCTACCAATTTTTGCTCTATCGCGACACGAACATACCCTAAATCTTACCGCTCTTTATCGCGGCGTAACACCAGTATA
CTTTGACGGCGATAGTGAAGGCGTGGCAGCAGCAATTAATGCTACTAATTTACTGAGAGATAAAGGTTTCTTGAAATCTG
GTGATCTAGTCATCATCACCCAGGGGGATGTAATGGATCTAGTAGGTACTACAAACACCAGTCGTATTCTGCGCGTCAAG
TAA

Protein sequence : 
MSRQLRRTKIVTTLGPVTDRDNNLEKVINAGANVVRLNFSHGSAEEHILRAQKVRDISARLGRHIAVLGDLQGPKIRIST
FRDGNIVLKVSDKFLLDASLGRGEGDCERVGIDYKGLPEDVAPGDILLLDDGRVQLKVLEVQGIRVYTQVTVGGPLSNNK
GINKLGGGLSAEALTEKDKSDIITAAKIGVDYLAISFPRTSEDLNYARRLAREAGSYAKIVSKIERAEAVATEEAMDEII
LASDVVMVARGDLGVEIGDPELVGIQKTLIRRARTLNRAVITATQMMESMINNPMPTRAEVMDVANAVLDGTDAVMLSAE
TAAGRYPAETVSTMASVCLGAEKIPSINLSKHRLDVQFDNIEEAIAMAAMYAANHLKGVTAIISMTESGSTALMMSRISS
GLPIFALSRHEHTLNLTALYRGVTPVYFDGDSEGVAAAINATNLLRDKGFLKSGDLVIITQGDVMDLVGTTNTSRILRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-80 50
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-53 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_007864444.1 Pyruvate kinase II VFG0479 Protein 1e-53 44