Gene Information

Name : F750_4921 (F750_4921)
Accession : YP_007861843.1
Strain : Streptomyces sp. PAMC26508
Genome accession: NC_021055
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 5105394 - 5106821 bp
Length : 1428 bp
Strand : -
Note : -

DNA sequence :
ATGCGCCGTTCCAAAATCGTCTGCACCCTCGGTCCCGCCGTCGACTCCCATGAGCAGCTCGTCGCTCTGATCGAGGCCGG
CATGAGCGTGGCCCGCTTCAACTTCAGTCACGGCACCCACGAGGAGCACCAAGGCCGTTACGACCGCGTCCGCAAGGCCG
CCGCCGAGACCGGCCGCGCCGTCGGCGTGCTCGCCGACCTCCAGGGCCCGAAGATCCGTCTCGGGAAGTTCGCCGAGGGT
CCGGTCGAGCTGGTCCGCGGGGACGAGTTCGTCATCACCTCCGAGGACGTCCCGGGCGACAAGTCGGTCTGCGGCACCAC
CTACAAGGGGCTGCCCGGCGACGTCGTCAAGGGTGACCCGATCCTGATCAACGACGGCAACGTCGAGCTGAAGGTCGTCT
CGGTCGACGGTCCGCGGGTCACCACCATCGTCATCGAGGGCGGTGTCATCTCCGACCACAAGGGGATCAACCTCCCGGGT
GCGGCGGTCAACGTCCCCGCGCTGTCCGAGAAGGACGTCGAGGACCTGCGCTTCGCCCTGCGGATGGGCTGCGACCTGGT
CGCGCTGTCCTTCGTGCGGGACGCCGAGGACGTCAAGGACGTGCACAAGGTGATGGACGAGGAGGGCCGCCGGGTCCCCG
TCATCGCCAAGGTCGAGAAGCCGCAGGCCGTCGAGCACATGGAGGGCGTCGTCGCCGCCTTCGACGGTGTGATGGTGGCC
CGTGGTGACCTCGCCGTCGAGTATCCGCTCGAGAAGGTCCCGATGGTGCAGAAGCGCCTCATCGAGCTGTGCCGCCGCAA
CGCCAAGCCGGTGATCGTGGCGACCCAGATGATGGAGTCGATGATCACCAACTCGCGCCCGACCCGCGCCGAGGCGTCCG
ACGTCGCCAACGCGATCCTGGACGGCGCGGACGCGGTCATGCTGTCGGCGGAGTCCTCGGTCGGCGCGTACCCGATCGAG
ACGGTCAAGACGATGTCGAAGATCGTCGTCGCCGCCGAGGAGGAGCTCCTGTCCAAGGGCCTCCAGCCGCTGGTGCCGGG
CAAGAAGCCGCGTACCCAGGGTGGTTCGGTGGCCCGCGCGGCCTGCGAGATCGCGGACTTCCTGGACGGCAAGGCCCTCG
TCGCCTTCACCAAGTCCGGTGACACCGCCCGCCGCCTCTCCCGCTACCGCACGGCACAGCCGATCCTGGCCTTCACCACG
GAGGAGTCCACCCGCAGCCAGCTCGCGCTGAGCTGGGGCGTCGAGTCCTACGTCGTGCCGCACGTGGACAACACGGACGC
CATGGTCGACCTGGTGGACGCCGAGCTGCTGAAGCTGAACCGCTACAGCGACGGCGACACGATGGTCATCACGGCCGGCT
CGCCCCCCGGCGTCCCCGGAACCACCAACATGGTCCGGGTGCACCACCTGAGCGGCGAGCGCGCCTGA

Protein sequence :
MRRSKIVCTLGPAVDSHEQLVALIEAGMSVARFNFSHGTHEEHQGRYDRVRKAAAETGRAVGVLADLQGPKIRLGKFAEG
PVELVRGDEFVITSEDVPGDKSVCGTTYKGLPGDVVKGDPILINDGNVELKVVSVDGPRVTTIVIEGGVISDHKGINLPG
AAVNVPALSEKDVEDLRFALRMGCDLVALSFVRDAEDVKDVHKVMDEEGRRVPVIAKVEKPQAVEHMEGVVAAFDGVMVA
RGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIE
TVKTMSKIVVAAEEELLSKGLQPLVPGKKPRTQGGSVARAACEIADFLDGKALVAFTKSGDTARRLSRYRTAQPILAFTT
EESTRSQLALSWGVESYVVPHVDNTDAMVDLVDAELLKLNRYSDGDTMVITAGSPPGVPGTTNMVRVHHLSGERA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-69 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-77 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
F750_4921 YP_007861843.1 pyruvate kinase VFG0479 Protein 9e-78 41