Gene Information

Name : mecB (F750_3236)
Accession : YP_007860189.1
Strain : Streptomyces sp. PAMC26508
Genome accession: NC_021055
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3407602 - 3410127 bp
Length : 2526 bp
Strand : -
Note : -

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGTCAGGGGCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACCCCCCGGGCCAAGAAGGTCCTGGAGCTGTCGCTCCGTGAGGCCCTTCAGCTCGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTGAAGCTGGGCGCCGACCTGAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGGTACTCGGGAGGCAAGGAGGCTGCCACCGCCGGCGGCCCCGCGGAGGGC
ACGCCCTCCACGTCTCTGGTGCTCGACCAGTTCGGCCGGAATCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGT
CATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTGCTCATCGGTG
AGCCCGGCGTCGGCAAGACGGCTGTCGTCGAGGGCCTGGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAG
GACAAGCACCTCTACACCCTCGACCTCGGTGCCCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAA
GAAGGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACACCCTCGTGGGTGCGGGTG
CCGCCGAGGGCGCGATCGACGCCGCGAGCATCCTCAAGCCGATGCTGGCGCGGGGCGAGCTGCAGACCATCGGTGCCACG
ACGCTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCCGCGCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCC
GTCGCTGCCGCACACCATCGAGATCCTCAAGGGGCTCCGCGACCGTTACGAGGCCCACCACAGGGTCTCCATCACGGACG
AGGCGCTGGTCCAGGCCGCCACCCTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATC
GACGAGGCCGGCTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCGGG
CGTCCGCCGCGACAAGGAGTCGGCGATCGACTCCCAGGACTTCGAGAAGGCAGCTTCGCTCCGCGACAAGGAGAAGCAGC
TGCTGGCGGCGAAGGCCAAGCGCGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTGGCCGAGGTCGACGGCGAGCTC
ATCGCCGAGGTCCTCGCCACCGCGACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGTCTGCTGCGCAT
GGAGGACGAGCTCCACAAGCGCGTCATCGGGCAGAAGGACGCCATCAAGGCCCTCTCGCAGGCGATCCGTCGTACGCGAG
CCGGCCTGAAGGACCCGAAGCGCCCCGGTGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACGGAGCTCTCC
AAGACGCTCGCCGAATTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACAC
GGTTTCCCGTCTCTTCGGTTCGCCCCCCGGTTACGTGGGTTACGAAGAGGGCGGTCAGCTCACCGAGAAGGTGCGCCGTA
AGCCGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCCGATATCTTCAACTCCCTGCTCCAGATTCTGGAG
GACGGTCGTCTGACCGACTCCCAGGGTCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGGAC
CAGGGACATCTCGAAGGGCTTCAACCTGGGCTTCGCCGCCCAGGGCGACGTCAAGACGAACTACGAGCGGATGAAGGTCA
AGGTCAACGAAGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTCGACGACACGGTCGTCTTCCACCAGCTC
ACCGAGGAAGACATCATCCAGATCGTCGACCTCATGGTCGCCAAGGTGGACGAGCGTCTCAAGGACCGTGACATGGGCAT
CGAGCTCAGTGCCGAGGCCAAGTCGCTCCTGGCGAAGAAGGGCTACGACCCCGTGATGGGCGCCCGGCCGCTGCGCCGGA
CGATCCAGCGCGAGATCGAGGACATCCTCTCCGAGAAGATCCTCTTCGGTGAGCTGCGTCCCGGTCACATCGTGGTCGTC
GGCACCGAGGGCGAAGGGGACGAGAAGAAGTTCTCGTTCCGCGGCGAGGAGAAGTCCGCTCTGCCGGACGTCCCGCCGAT
CGAGCAGGCAGCGGGCGGCGGCCCGAACCTGACGAAGGAAGCGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYSGGKEAATAGGPAEG
TPSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLK
DKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGAT
TLDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLI
DEAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGEL
IAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELS
KTLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILE
DGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDVKTNYERMKVKVNEELKQHFRPEFLNRVDDTVVFHQL
TEEDIIQIVDLMVAKVDERLKDRDMGIELSAEAKSLLAKKGYDPVMGARPLRRTIQREIEDILSEKILFGELRPGHIVVV
GTEGEGDEKKFSFRGEEKSALPDVPPIEQAAGGGPNLTKEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mecB YP_007860189.1 ATP-dependent Clp protease VFG0079 Protein 0.0 62
mecB YP_007860189.1 ATP-dependent Clp protease VFG0080 Protein 1e-149 53