Gene Information

Name : J112_19360 (J112_19360)
Accession : YP_007856654.1
Strain : Mycobacterium tuberculosis Beijing/NITR203
Genome accession: NC_021054
Putative virulence/resistance : Virulence
Product : ATP-dependent protease ATP-binding subunit clpC1
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4037760 - 4040306 bp
Length : 2547 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAACGATTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCTCAGGAAGAGGCCAGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATTCTTTTAGGCCTGATCCATGAAGGGGAAGGCGTTGCCGCCAAGTCACTGGAGTCGTTGGGGA
TCTCGCTGGAAGGTGTGCGCAGTCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCTGGGCACATTCCGTTT
ACCCCCCGCGCCAAAAAGGTCCTCGAGCTGAGCTTGCGTGAAGCGCTGCAGCTTGGCCACAACTACATCGGGACCGAACA
CATTTTGCTGGGCCTCATCCGAGAGGGTGAAGGCGTGGCCGCCCAGGTGCTGGTCAAGCTGGGCGCCGAGCTGACCCGGG
TGCGCCAGCAGGTGATCCAGCTGCTCTCCGGTTACCAAGGCAAGGAGGCCGCCGAAGCCGGCACCGGCGGCCGCGGGGGA
GAGTCCGGCTCTCCGTCTACGTCCTTGGTGCTCGACCAGTTCGGCCGCAACCTCACGGCGGCGGCGATGGAAGGCAAACT
GGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTCTCTCGGCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGCGTCGGCAAGACCGCGGTCGTCGAAGGACTGGCGCAGGCCATCGTGCACGGCGAGGTGCCCGAG
ACGCTCAAGGACAAGCAGCTCTACACGCTGGATCTGGGATCGCTGGTGGCGGGTAGCCGCTACCGCGGTGACTTCGAGGA
ACGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGCGGTGACATCATCCTGTTTATCGACGAGCTGCACACCTTGGTCG
GTGCTGGAGCCGCCGAGGGCGCGATCGACGCCGCCTCGATCCTGAAACCGAAGCTCGCTCGCGGTGAACTGCAAACGATC
GGCGCCACCACGCTCGACGAATACCGCAAGTACATCGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCGGTGCAGGT
GGGTGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGCCTGCGGGACCGGTACGAGGCGCACCACCGGGTGTCGA
TCACCGATGCGGCGATGGTGGCCGCCGCGACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCCGACAAGGCGATC
GACCTGATCGACGAGGCGGGTGCTCGGATGCGGATTCGTCGCATGACCGCACCGCCAGACCTACGCGAGTTCGATGAGAA
GATCGCCGAGGCTCGTCGGGAGAAGGAATCGGCTATCGACGCCCAGGACTTCGAGAAGGCCGCCAGCCTGCGCGACCGGG
AGAAGACACTGGTCGCACAGCGTGCTGAGCGCGAAAAGCAGTGGCGTTCAGGCGATCTTGACGTGGTCGCGGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGTATCCCGGTGTTCAAGCTCACCGAGGCCGAGACCACCCGGCT
GTTGCGGATGGAAGAAGAGCTGCACAAGCGGATCATCGGGCAAGAGGACGCCGTCAAGGCCGTTTCCAAGGCCATCCGGC
GTACCCGGGCCGGGCTGAAAGACCCCAAGCGCCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAACTGTCCAAGGCGCTGGCCAACTTCTTGTTCGGTGACGACGACGCGCTTATTCAGATTGACATGGGTGAATTCCACGA
CCGGTTCACCGCGTCGCGGCTATTCGGCGCGCCGCCCGGATACGTCGGCTACGAGGAGGGCGGCCAACTCACCGAGAAGG
TGCGGCGCAAGCCGTTCTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCGCATCAGGAGATCTACAACAGCCTGCTGCAG
GTGCTCGAGGATGGCCGGCTCACCGACGGGCAGGGCCGCACGGTGGACTTCAAGAACACCGTGCTGATCTTTACGTCCAA
TCTGGGCACCTCCGACATCTCTAAGCCGGTCGGTCTGGGCTTTTCCAAGGGCGGCGGTGAGAACGACTACGAGCGGATGA
AACAGAAGGTCAACGACGAGCTGAAGAAACACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACCCGCGAGGAGATCATCCGGATGGTCGACCTGATGATCAGCCGGGTCGCCGGCCAGCTCAAGAGCAAGGACAT
GGCGCTGGTGCTGACCGATGCGGCCAAGGCGCTGCTGGCCAAGCGTGGCTTCGACCCGGTGTTGGGGGCCCGCCCGTTGC
GGCGCACCATCCAGCGTGAGATCGAAGATCAGCTCTCGGAGAAGATCCTCTTCGAGGAGGTCGGGCCGGGTCAGGTGGTC
ACCGTCGACGTGGACAACTGGGACGGTGAAGGTCCCGGCGAGGACGCGGTGTTCACCTTCCCCGGTCCCCGCAAGCCGCC
GGCCGAGCCGGATCTGGCCAAGGCTGGAGCGCACAGCGCGGGCGGCCCGGAGCCGGCCGCGCGGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTREEIIRMVDLMISRVAGQLKSKDMALVLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVV
TVDVDNWDGEGPGEDAVFTFPGPRKPPAEPDLAKAGAHSAGGPEPAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
J112_19360 YP_007856654.1 ATP-dependent protease ATP-binding subunit clpC1 VFG0079 Protein 0.0 60
J112_19360 YP_007856654.1 ATP-dependent protease ATP-binding subunit clpC1 VFG0080 Protein 9e-140 51