Gene Information

Name : tpx (J112_10295)
Accession : YP_007854898.1
Strain : Mycobacterium tuberculosis Beijing/NITR203
Genome accession: NC_021054
Putative virulence/resistance : Virulence
Product : lipid hydroperoxide peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2183178 - 2183675 bp
Length : 498 bp
Strand : +
Note : COG2077 Peroxiredoxin

DNA sequence :
ATGGCACAGATAACCCTGCGAGGAAACGCGATCAATACCGTCGGTGAGCTACCTGCTGTCGGATCCCCGGCCCCGGCCTT
CACCCTGACCGGGGGCGATCTGGGGGTGATCAGCAGCGACCAGTTCCGGGGTAAGTCCGTGTTGCTGAACATCTTTCCAT
CCGTGGACACACCGGTGTGCGCGACGAGTGTGCGAACCTTCGACGAGCGTGCGGCGGCAAGTGGCGCTACCGTGCTGTGT
GTCTCGAAGGATCTGCCGTTCGCCCAGAAGCGCTTCTGCGGCGCCGAGGGCACCGAAAACGTCATGCCCGCGTCGGCATT
CCGGGACAGCTTCGGCGAGGATTACGGCGTGACCATCGCCGACGGGCCGATGGCCGGGCTGCTCGCCCGCGCAATCGTGG
TGATCGGCGCGGACGGCAACGTCGCCTACACGGAATTGGTGCCGGAAATCGCGCAAGAACCCAACTACGAAGCGGCGCTG
GCCGCGCTGGGCGCCTAG

Protein sequence :
MAQITLRGNAINTVGELPAVGSPAPAFTLTGGDLGVISSDQFRGKSVLLNIFPSVDTPVCATSVRTFDERAAASGATVLC
VSKDLPFAQKRFCGAEGTENVMPASAFRDSFGEDYGVTIADGPMAGLLARAIVVIGADGNVAYTELVPEIAQEPNYEAAL
AALGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-33 44
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-33 44
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-33 43
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-33 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_007854898.1 lipid hydroperoxide peroxidase VFG0087 Protein 4e-34 44