Gene Information

Name : CLS_04310 (CLS_04310)
Accession : YP_007848253.1
Strain : Clostridium saccharolyticum K10
Genome accession: NC_021047
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 424843 - 426279 bp
Length : 1437 bp
Strand : +
Note : -

DNA sequence :
ATGAAAAAGACAAAAATTATCTGCACCATGGGCCCGAACACCAATGACAGAGAGATTATGAGACAGCTTGCTTTAAATGG
AATGGATGTGGCGCGTTTTAATTTTTCCCACGGAGATTACGAGGAGCATATGGGCCGCTATAAGATCCTCGAGAGTGTGC
GTGAAGAGCTGGGGCTTCCAATCGCAGCCCTGCTTGACACCAAGGGTCCGGAGATTCGCACGGGAAATCTGAAGGACGGA
AAGAAGGTCACTCTGAAGGCGGGAGAACTTTATACGCTCACCACAGATGAAATCGTGGGTGACGACAGGAGAGGCTTCAT
CAACTATGCAGGGCTTCCCGCTGATGTGGTGCCGGGAAATCAGATCCTTATTGACGACGGACTGATTGAGCTGGATGTGG
AAGAAGTAAGGGGAAATGATATTGTCTGCAGAATCATCAATGGAGGTGAGCTTGGGGAGAAGAAGGGAGTCAATGTACCA
AATGTGGAAATTAAGCTCCCGGCTCTGACCGACAAGGACAAGGAGGATATCCTCTTTGGAATCACGGCCGGATTTGACAT
GATCGCGGCCTCCTTTGTCAGAAATGCATCTGCAATCCGTGAGATTCGTGAGATTCTGGATAAGCATGGTTCCAATATGC
TTATTATTGCAAAGATTGAGAATGCAGAGGGTATCAAAAATCTGGATTCCATCCTGGAAGCCTGCGATGGAATTATGGTT
GCCCGAGGTGATATGGGAGTTGAGATTCCGGCAGAGAAGGTTCCTCATATACAGAAGCTGATTATCCGAAAGTGCAATGA
GGCCTGTAAGCCGGTTATCACAGCAACCCAGATGCTGGACTCCATGATCAGGAATCCCCGTCCAACCCGTGCGGAAGTGA
CAGACGTGGCCAATGCCGTTTATGACGGAACAGACGCAGTGATGCTCTCCGGGGAGACAGCTATGGGACGCTACCCGGTG
GAGGCGGTAAAGATGATGGCTCAGATCGTGGAAGATTCTGAGAAGTATCTGGACTATTCGTCCTATCGTCAGAGAAGGGT
CAGTGTGGAAAATAAGAAAAATATCTCCAACGCAGTGTGCTATTCATCCGTAGCCACAGCCCATGATCTGGGCGCAGCTG
CGATTGTGGCGCCTTCTGTCAGCGGATTTACAGCGAGAATGCTCTCCAAATGGCGTCCCAACGCGACGATTGTGGGACTC
TCACCGAGCATGACAACGGTCCGCCAGATGCAGCTCTACTGGGGGGTGAAGCCGTTCCACGCAAAGAGGGCAGATTCCAC
CGACGTTCTGGTATATTCTTCTATCGAGATTCTGAAGGAAAAGGGAATCGTAAAGGCAGGAGATGTGGTTGTGGCTACTG
CCGGAGTTGTGACTTATGCAAGCCGGCATTCTCCGGCAGCTAATACCAATATCATGCGCGTGGTTGAGGTGGACTAA

Protein sequence :
MKKTKIICTMGPNTNDREIMRQLALNGMDVARFNFSHGDYEEHMGRYKILESVREELGLPIAALLDTKGPEIRTGNLKDG
KKVTLKAGELYTLTTDEIVGDDRRGFINYAGLPADVVPGNQILIDDGLIELDVEEVRGNDIVCRIINGGELGEKKGVNVP
NVEIKLPALTDKDKEDILFGITAGFDMIAASFVRNASAIREIREILDKHGSNMLIIAKIENAEGIKNLDSILEACDGIMV
ARGDMGVEIPAEKVPHIQKLIIRKCNEACKPVITATQMLDSMIRNPRPTRAEVTDVANAVYDGTDAVMLSGETAMGRYPV
EAVKMMAQIVEDSEKYLDYSSYRQRRVSVENKKNISNAVCYSSVATAHDLGAAAIVAPSVSGFTARMLSKWRPNATIVGL
SPSMTTVRQMQLYWGVKPFHAKRADSTDVLVYSSIEILKEKGIVKAGDVVVATAGVVTYASRHSPAANTNIMRVVEVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-96 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-96 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-96 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-95 52
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-50 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLS_04310 YP_007848253.1 pyruvate kinase VFG0479 Protein 1e-96 52