Gene Information

Name : ENC_21390 (ENC_21390)
Accession : YP_007845833.1
Strain : Enterobacter cloacae NCTC 9394
Genome accession: NC_021046
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 2181650 - 2183260 bp
Length : 1611 bp
Strand : -
Note : -

DNA sequence :
ATGACCATCCCTTTTACCCGCTGGCCTGAGGAGTTTGCCCGCCGCTACCGTGAAAAAGGCTACTGGCAGGATCTGCCGCT
GACCCACATCCTGACGGACCATGCGGACAGCGATGCGGTCGCAATAATTGACGGCGATCGCCGCATCACCTACCGCGCGT
TTAATCAGGCGGTGACGAATCTGGCGTCTGTCCTTCAGGCGCAGGGGCTGCATCGCGGCGAGACCGCGCTGGTGCAGCTC
GGCAACGTGGCCGAGTTCTACATCACCTTCTTCGCGCTGCTGCAAATCGGCGTCGCGCCGGTCAACGCGCTCTTTAGCCA
TCAGCGCAGCGAACTCAACGCCTACGCGGAGCAGATCAAACCCGCCGTGCTGATTGCCGACCGCGACCACACGCTGTTCG
CGGGTGATGATTTTCTCAATACCTTTGTGGATGCGCATCGCTCGGTACGCGTTGTGCTGCTACGCGGCGATAAGGGCGAA
CACGCGCTGGAGGCGGCGATTGCACGCCCGGCGGACAATTTCATCCCGAACCCGACGCCCGCCGACGAAGTGGCGTTCTT
CCAGCTCTCCGGCGGCAGCACCGGCACGCCGAAGCTGATCCCGCGTACGCACAACGACTACGACTACAGCATCCGTCGCA
GCAACGAAATCTGCGGAATCACTGCGCACACCCGCTATCTGAACGCACTTCCCGCGGCGCATAACTACGCCATGAGCTCG
CCGGGATCGTTAGGCGTTTTCACGGCGGGCGGCTGCGTGGTGCTGGCGAACGATCCGAGCGCCACGCTCTGCTTCCCGCT
GATTGAGCAGCATCAGATAAACGTCACCTCACTGGTGCCGCCCGCGGTCAGCCTGTGGTTGCAGGCGATTGCCGACGGCG
CGGGGAACGCCCAGCTGAAATCCCTCGAACTGCTCCAGGTAGGCGGCGCACGTCTCTCCGCCACGCTTGCGGCACGTATT
CCGGCGGAAATTGGCTGCCAGCTTCAGCAGGTGTTTGGCATGGCGGAAGGGCTGGTGAACTACACCGCCCTCGACGATGC
GCCGGAGCGCATCATCAATACCCAGGGCCGCCCGATGTGCCCGGACGATGAAGTGTGGGTGGCGGACGAGGACGGCAACC
CGCTGCCGCGCGGGGAAGTCGGGCGTCTGATGACGCGCGGCCCTTACACCTTCCGCGGCTATTTCAATAGCCCGGAACAC
AACGCCAGCGCCTTTGATGCCAACGGTTTCTACTGCTCGGGCGATCTGATCGCCATCGATGAGCAGGGTTACATCACCGT
GCAGGGGCGCGAGAAAGATCAGATCAACCGCGGTGGCGAGAAGATCGCCGCCGAAGAGATCGAAAACCTGCTGCTGCGCC
ACGACGCGGTGATCCACGCCGCGCTGGTGAGCATGGAGGACAGCCTGCTGGGCGAAAAAAGCTGCGCGTACCTGGTGGTG
AAACAGCCCCTGCGCGCGGTGGAGGTGCGCCGCTTCCTGCGCGAGCAGGGCGTCGCCGAATTTAAGCTGCCGGACCGCGT
GGAGAGCGTGGATGCGCTTCCGCTCACGCCGGTCGGCAAAGTTGATAAGAAACAGTTGCGCCTGTGGCTTGCTGAACGCG
CCCGGGGCTGA

Protein sequence :
MTIPFTRWPEEFARRYREKGYWQDLPLTHILTDHADSDAVAIIDGDRRITYRAFNQAVTNLASVLQAQGLHRGETALVQL
GNVAEFYITFFALLQIGVAPVNALFSHQRSELNAYAEQIKPAVLIADRDHTLFAGDDFLNTFVDAHRSVRVVLLRGDKGE
HALEAAIARPADNFIPNPTPADEVAFFQLSGGSTGTPKLIPRTHNDYDYSIRRSNEICGITAHTRYLNALPAAHNYAMSS
PGSLGVFTAGGCVVLANDPSATLCFPLIEQHQINVTSLVPPAVSLWLQAIADGAGNAQLKSLELLQVGGARLSATLAARI
PAEIGCQLQQVFGMAEGLVNYTALDDAPERIINTQGRPMCPDDEVWVADEDGNPLPRGEVGRLMTRGPYTFRGYFNSPEH
NASAFDANGFYCSGDLIAIDEQGYITVQGREKDQINRGGEKIAAEEIENLLLRHDAVIHAALVSMEDSLLGEKSCAYLVV
KQPLRAVEVRRFLREQGVAEFKLPDRVESVDALPLTPVGKVDKKQLRLWLAERARG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 42
ybtE CAA21394.1 - Virulence HPI Protein 3e-90 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-90 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-90 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-90 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-90 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-90 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-90 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ENC_21390 YP_007845833.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 0.0 81
ENC_21390 YP_007845833.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-112 46