Gene Information

Name : ROI_20930 (ROI_20930)
Accession : YP_007832158.1
Strain : Roseburia intestinalis M50/1
Genome accession: NC_021040
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 2110093 - 2111400 bp
Length : 1308 bp
Strand : +
Note : -

DNA sequence :
ATGGGTACATTTGATAAATATCTTCAGCTTGCCGATAAGACGTATTTTAACCGTTTAGGCAAGGTGACAAAGATTGTCGG
TCTTACAATTGAATCTGTAGGACCAAATGCAAAACTGAATGATCTGTGCCGTATCATTATCGATCGGGAACAAAATATTT
CAACGATGGCTGAAGTCGTCGGTTTCCGTGATAAACATTTACTCCTGATGCCGTTTGAAAGCGTAGAAGGAATTGGTGTT
GGATGTATTGTAGAAAATACAGGACATCCTCTGACGGTAAAAGTTGGAGAAGAACTGTTAGGTCATACATTAGATGGAAT
AGGACGGCCAACCGATGTGGAAGAACTGTCACTTTCCTATGATTATCCGGTTGAAGCATTGCCACCAGATCCGATGGCAA
GAAAAATTATTGATGAAGTACTACCTTTGGGTGTGAAAGCAGTAGATGGTCTGATTACAGTAGGAAAAGGACAGAGAATC
GGTATTTTCGCCGGATCCGGTGTTGGAAAAAGTACATTACTTGGTATGTTTGCGAGAAATACAAAAGCGGATATCAACGT
GATTGCATTGATTGGCGAGCGTGGAAGAGAAGTAAGAGAGTTTGTGGAACGCGATCTTGGTGAAGAAGGCATGAAACGCT
CCGTGGTTATTGTTGCGACATCCGATAAACCTGCATTGATAAGAAATAAAGCTGCAAAAACAGCAACAGCTATTGCTGAA
TACTTTAGAGATCAGGGGAAAGATGTGTTGCTGATGATGGATTCACTGACACGATTTTCTATGGCACAGCGGGAGATTGG
GTTGGCATCCGGAGAGCCACCGGTAACAAGAGGATATCCACCAAGTGTGTATTCAGAAATGCCTAAACTTCTGGAACGTG
CAGGAACTTCGGATAAGGGATCTATTACCGGACTTTACACCGTGCTTGTAGATGGTGATGATATGAATGAACCAATCACA
GATACGGCGAGAAGTATTCTGGATGGACATATTATGTTATCCAGAAAATTAGGACAGAAGAATCATTATCCTGCAATTGA
TGTATTACAGAGTATTTCCCGTGTTATGAGTTCGATTGCTACAAGTGAGCATAAAGAGCTTGCCGGAAAATTAAGAAATG
TTATGGCTACTTATAATGAGGCAGAAGACCTGATTAATATCGGGGCATATAAAAATGGAACCAATCGTGAAATTGATTAT
GCAATTCAAAAAAATCAAGCGGTAAATGAGTTCCTGATGCAAAAGACCGATGAAAAATTTGAATTCAACGAAGAGATTGA
CCTGCTGCGAAAACTGTTTGAAAACTAA

Protein sequence :
MGTFDKYLQLADKTYFNRLGKVTKIVGLTIESVGPNAKLNDLCRIIIDREQNISTMAEVVGFRDKHLLLMPFESVEGIGV
GCIVENTGHPLTVKVGEELLGHTLDGIGRPTDVEELSLSYDYPVEALPPDPMARKIIDEVLPLGVKAVDGLITVGKGQRI
GIFAGSGVGKSTLLGMFARNTKADINVIALIGERGREVREFVERDLGEEGMKRSVVIVATSDKPALIRNKAAKTATAIAE
YFRDQGKDVLLMMDSLTRFSMAQREIGLASGEPPVTRGYPPSVYSEMPKLLERAGTSDKGSITGLYTVLVDGDDMNEPIT
DTARSILDGHIMLSRKLGQKNHYPAIDVLQSISRVMSSIATSEHKELAGKLRNVMATYNEAEDLINIGAYKNGTNREIDY
AIQKNQAVNEFLMQKTDEKFEFNEEIDLLRKLFEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-99 55
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-97 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-97 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-97 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-97 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-98 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-98 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-98 51
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-84 51
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-96 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-96 50
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-86 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 8e-85 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-85 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-82 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-84 49
escN AAC31513.1 L0034 Virulence LEE Protein 2e-84 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-84 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-84 49
escN AAK26715.1 EscN Virulence LEE Protein 1e-84 49
escN AAL57542.1 EscN Virulence LEE Protein 1e-84 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-85 49
escN AAC38383.1 EscN Virulence LEE Protein 1e-84 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-85 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-84 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-84 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-82 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-82 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-83 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-83 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-83 49
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-79 49
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-72 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-72 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-73 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 9e-75 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-74 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-75 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 6e-76 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-76 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-80 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-70 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-70 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-67 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-65 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-65 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-65 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-65 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 3e-101 55
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 7e-98 55
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 2e-103 54
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 3e-101 53
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 6e-85 49
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 1e-84 49
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 2e-83 49
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 6e-84 47
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 3e-81 46
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 8e-81 46
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 3e-67 42
ROI_20930 YP_007832158.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 4e-66 41