Gene Information

Name : guaA (SPN994038_12590)
Accession : YP_007813023.1
Strain : Streptococcus pneumoniae SNP994038
Genome accession: NC_021026
Putative virulence/resistance : Unknown
Product : GMP synthase [glutamine-hydrolyzing]
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1281164 - 1282726 bp
Length : 1563 bp
Strand : -
Note : -

DNA sequence :
ATGAGCAACATTTCAACTGATTTGCAAGATGTAGAAAAAATCATCGTATTGGACTATGGTAGCCAGTACAACCAGCTGAT
TTCACGCCGTATCCGTGAGATTGGTGTTTTTTCAGAACTAAAAAGCCATAAAATTTCAGCTGCTGAAGTTCGTGAAGTCA
ATCCTGTAGGAATTATTCTATCAGGTGGTCCAAATTCTGTATATGAAGATGGTTCATTTGACATTGACCCAGAAATCTTC
GAACTAGGAATTCCAATTTTGGGAATCTGTTATGGTATGCAGTTATTGACCCATAAACTTGGAGGAAAAGTTGTTCCTGC
AGGTGATGCTGGAAATCGTGAATACGGTCAATCAACCCTAACTCACACACCATCAGCGCTTTTTGAATCAACACCTGATG
AACAGACTGTTTTGATGAGCCATGGTGATGCGGTTACTGAGATTCCTGCTGACTTTGTTCGTACAGGTACATCAGCTGAC
TGCCCATACGCAGCCATCGAAAACCCAGATAAACACATTTACGGTATCCAATTCCACCCAGAAGTTCGTCATTCTGTATA
CGGAAATGATATCCTTCGTAACTTTGCCCTTAACATTTGTAAGGCTAAAGGTGACTGGTCAATGGATAATTTCATTGACA
TGCAGATCAAAAAAATTCGTGAAACCGTCGGTGATAAACGTGTCCTTCTTGGTCTATCAGGTGGTGTTGACTCATCTGTC
GTTGGGGTTCTTCTCCAAAAAGCGATTGGCGATCAATTGATCTGTATCTTCGTAGACCACGGTCTTCTTCGTAAAGGCGA
AGCTGATCAAGTTATGGACATGCTCGGTGGTAAGTTTGGTTTGAATATCGTCAAAGCAGACGCTGCTAAACGTTTCCTTG
ACAAACTTGCTGGCGTTTCTGACCCTGAACAAAAACGTAAAATCATCGGTAACGAGTTTGTCTATGTATTCGATGACGAA
GCAAGCAAGCTCAAAGATGTGAAATTCCTTGCTCAAGGTACTTTATATACAGATGTTATCGAGTCTGGTACGGATACAGC
TCAAACTATCAAGTCACACCACAACGTGGGTGGTCTTCCAGAAGATATGCAGTTTGAATTGATTGAACCACTCAATACTC
TTTACAAGGATGAAGTTCGTGCTCTTGGTACAGAGCTTGGTATGCCAGACCATATCGTATGGCGCCAACCATTCCCAGGA
CCAGGACTTGCTATCCGTGTCATGGGTGAAATCACTGAAGAGAAACTTGAAACCGTTCGTGAATCAGACGCTATTCTTCG
TGAAGAAATCGCTAAAGCTGGACTTGACCGCGATATTTGGCAATACTTCACTGTTAACACAGGCGTTCGTTCAGTCGGCG
TTATGGGTGACGGTCGTACGTATGACTACACGATTGCAATCCGTGCTATCACTTCTATCGATGGTATGACTGCTGATTTT
GCCAAAATTCCATGGGAAGTACTTCAAAAAATCTCAGTACGTATCGTAAATGAAGTGGATCATGTTAACCGTATCGTCTA
CGATATTACAAGTAAACCACCTGCAACAGTTGAGTGGGAATAA

Protein sequence :
MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHKISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIF
ELGIPILGICYGMQLLTHKLGGKVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKKIRETVGDKRVLLGLSGGVDSSV
VGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLGGKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDE
ASKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHIVWRQPFPG
PGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AKIPWEVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-176 71
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-176 71
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-176 71
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-122 51