Gene Information

Name : EC1_04100 (EC1_04100)
Accession : YP_007797708.1
Strain : Eubacterium cylindroides T2-87
Genome accession: NC_021019
Putative virulence/resistance : Resistance
Product : D-alanine--D-alanine ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.2.4
Position : 389588 - 390631 bp
Length : 1044 bp
Strand : +
Note : -

DNA sequence : 
ATGTTGAAATTAGGTGTTGTCTTTGGTGGACAGAGTAGTGAGTATTCTGTTTCTTTACACTCTGTTGCTTCTTTTTTAAG
ACAGATTCATAATGAAAAATACGATATTACTATGATTGGTATCGACCAGAATGGGCAATTTTATGTTTATGATGGTTCGA
TTGATGATATAGAACATGATCATTGGATTCCTCAGGCTACAAAAGCTGCATGGGTTCATAAAGGAATCATGGCTTTGGAT
GGAAAGAATACAGTAAAAGAATTAGATTGTGTATTCCCTGTTTTACATGGAAAAAATGGGGAAGATGGATGTGTGCAGGG
GTTATTGGAATTGATGAATATCCATTATGTTGGATGTGATGTAATGTCTAGTGCAATTTCTATGGATAAAGAGATCATGC
ATATTTTATGTGATGAAGCTAACATACCTTGCGCTGATTATGTTTGTTTAAAAGCCAATGAAGAAAATCCTTCATTTGAA
ATGATCCAGGAAAAGATTTCCCTACCTTGGATCGTAAAACCATGTAATGCCGGAAGTAGTTATGGTGTTCATAAAGTAGA
GAATAAAGAAGAATTTGAAGAGGCTTGTAAAGATGCTTTCTTCTATGATGGCCGTGGCAAGATCTTAGTTGAAAAAGCAA
TTGAAGGCTTTGAGATTGGCTGTGCTGTTATGGGAAATGAAGAAGTGTTTACTGGCAGCTGTGATGAGATTCAAATTTCT
GGAGGAATTTTTGATTTTGAAGGAAAATATGAGATGAAAGGGGCTGAAATCATCTGCCCTGCACGAATCGATGAAGAAAC
GTTTGCCAAGGCTAAGGCCCTAGCAGCTAAAACATATAAAGCTATGAATTGTTGTGGTATGGCTCGTGTGGATATGTTTG
TAACGCCTCAAAAAGAGGTTATCTTAAATGAATTGAATACGATTCCAGGTTTTACCGCCACTTCACGTTATCCATCTATG
ATGAAAGAAGCTGGAATTGAATTCGGTGATTTAATTGATAAATTGATCGATCTAGCAATGCAAAGGACGATTTCAGCATG
TTAA

Protein sequence : 
MLKLGVVFGGQSSEYSVSLHSVASFLRQIHNEKYDITMIGIDQNGQFYVYDGSIDDIEHDHWIPQATKAAWVHKGIMALD
GKNTVKELDCVFPVLHGKNGEDGCVQGLLELMNIHYVGCDVMSSAISMDKEIMHILCDEANIPCADYVCLKANEENPSFE
MIQEKISLPWIVKPCNAGSSYGVHKVENKEEFEEACKDAFFYDGRGKILVEKAIEGFEIGCAVMGNEEVFTGSCDEIQIS
GGIFDFEGKYEMKGAEIICPARIDEETFAKAKALAAKTYKAMNCCGMARVDMFVTPQKEVILNELNTIPGFTATSRYPSM
MKEAGIEFGDLIDKLIDLAMQRTISAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanB NP_815951.1 D-alanine--D-lactate ligase Not tested Not named Protein 4e-44 41
vanB YP_008394259.1 Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase Not tested Not named Protein 3e-43 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EC1_04100 YP_007797708.1 D-alanine--D-alanine ligase AF162694.gene.p01 Protein 3e-58 42
EC1_04100 YP_007797708.1 D-alanine--D-alanine ligase U00456.gene.p01 Protein 2e-44 41
EC1_04100 YP_007797708.1 D-alanine--D-alanine ligase U35369.1.gene6.p01 Protein 2e-44 41
EC1_04100 YP_007797708.1 D-alanine--D-alanine ligase AE016830.1.gene2250. Protein 2e-44 41
EC1_04100 YP_007797708.1 D-alanine--D-alanine ligase AF310956.2.orf5.gene Protein 1e-43 41
EC1_04100 YP_007797708.1 D-alanine--D-alanine ligase AY145441.gene.p01 Protein 9e-44 41