Gene Information

Name : RBR_08310 (RBR_08310)
Accession : YP_007780949.1
Strain : Ruminococcus bromii L2-63
Genome accession: NC_021013
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 885044 - 886486 bp
Length : 1443 bp
Strand : +
Note : -

DNA sequence :
ATGAGGAAAACTAAGATAGTTTGTACCATCGGACCTGCCTGCGATTCAAAAGAAATGATGCGTAAAATGATTGACGCAGG
TATGAATGTTGCCAGAATCAATATGTCACACGGCGTTTATGACCGGCTTGAGGTTACAATCAAAAACCTTAAAGAGGCAA
TTGCAGAGAGTGGTCAAAATGTTGCAATTCTGCTCGATACAAAGGGTCCTGAGGTCAGAGTCGGCACATTCAAGGACGGT
TCTGTTGAACTTGTCGAGGGTGCAGAGTTCAGTCTTTTTAAAAACAAAGAAGAGGGCGACGAAACAGGTGTAAGCCTTTC
GTTTCCTAAGCTTGTTGATATTTTTGAATCCGAAGGTCAGGAGGCAATCGGCAGAGAGCTTTTGCTTGATGACGGTATTA
TCTCGCTTGTCGTTAAGTCGGTAAATCCCGAGTCAATCGTTTGTACCGTAAACAAGGGCGGTGTGCTTAAAAACCGCAAG
AGTATCAACATTCCGGGCTACTTTATCAATATGCCGTATGTAAGCGCTCAGGACAGAAAGGACATTGAGTTCGGTCTTAA
CCACGGTGCAACAGTTGTTGCCGCATCATTTGTCCGCAATCACGATGATGTTAGAACTCTTCGTGACTTTATTGACAGCC
TCGGCTATGAGTATGTTGAAATTATCGCAAAGATTGAAAATCAGAGCGGTGTTGACGATATGGACGCAATTATTGATTAC
GCAGACGGTATTATGGTTGCCCGTGGAGATATGGGCGTTGAAATTCCGTTTATCAAGCTGCCTGAAATTCAGAAAACAAT
CATAAGAAAGGTTGTTTCAAGAGGTAAGTATGTAATCACTGCAACCCAGATGCTTGAGAGTATGACAACGGCTCCCCGTC
CTACAAGAGCCGAAATCAGCGATGTTGCCAATGCAGTTTATGATGGCACAAGCGCAGTAATGCTTTCGGCAGAATCCGCC
GCAGGTAAGTACCCGATTGAAAGCGTAAAGGCACTTGACGCAATTTGTTCGGAGGCTGAGGAAAACGGTGAATTTACCGC
ACTTCATGAGTATGTGGAAGAACACGGAATGAAGGACACTAACCCAATCAGATCAAGTATCTGTAAAGCTGCAAAGAATA
TTGCACAGGCAGTAGGCGCAAAGGCTATTATTGTTGAAAGTGCAACAGGTCGAGTTGCAAGAGCGATGGTTCATTACAGA
CCTGACTGTCCCGTTATTGCAGTTGCAACATCACAGCTTGTGTGCAGAAAGCTCTGTCTTAACTGGGGTGTTATGGCTGT
CATGGGCGAAGAAAAACGCACATCTGATTCAATTACGAAACAGGCTATGGAAAAGGCACTCAGCACAGGCGTTGTCAAAA
AAGGCGACACGGTTGTTGTGCTTTCGTCAAACAAAACCTGCCCGACTTCAAGTACAGATTCACTTAATGTAAGGATTCTT
TAA

Protein sequence :
MRKTKIVCTIGPACDSKEMMRKMIDAGMNVARINMSHGVYDRLEVTIKNLKEAIAESGQNVAILLDTKGPEVRVGTFKDG
SVELVEGAEFSLFKNKEEGDETGVSLSFPKLVDIFESEGQEAIGRELLLDDGIISLVVKSVNPESIVCTVNKGGVLKNRK
SINIPGYFINMPYVSAQDRKDIEFGLNHGATVVAASFVRNHDDVRTLRDFIDSLGYEYVEIIAKIENQSGVDDMDAIIDY
ADGIMVARGDMGVEIPFIKLPEIQKTIIRKVVSRGKYVITATQMLESMTTAPRPTRAEISDVANAVYDGTSAVMLSAESA
AGKYPIESVKALDAICSEAEENGEFTALHEYVEEHGMKDTNPIRSSICKAAKNIAQAVGAKAIIVESATGRVARAMVHYR
PDCPVIAVATSQLVCRKLCLNWGVMAVMGEEKRTSDSITKQAMEKALSTGVVKKGDTVVVLSSNKTCPTSSTDSLNVRIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-75 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-75 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-75 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RBR_08310 YP_007780949.1 pyruvate kinase VFG0479 Protein 5e-76 41