Gene Information

Name : RBR_17480 (RBR_17480)
Accession : YP_007781707.1
Strain : Ruminococcus bromii L2-63
Genome accession: NC_021013
Putative virulence/resistance : Resistance
Product : D-alanine--D-alanine ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.2.4
Position : 1829885 - 1830934 bp
Length : 1050 bp
Strand : +
Note : -

DNA sequence :
ATGCAAAAGAAAAAAATAGCAGTTATTTTTGGAGGCAATTCAACAGAGTACGAGGTGTCATTACAATCGGCATTTTCCGT
GTTTGAAAATATCAATCATGATAAGTATGACATTATCCCCATAGGAATCACTCGAAACGGGGACTGGTATCACTACAAAG
GTCGGTATGAGAACATAGCAAATAATACTTGGAGCGGGGATCGGGACAATCTCTATCCTGTGACCGTATCTGTAAGTCAC
TCTCAAAAGGGCATTTGGGAATTTGACGAGGATCAATACACTGCTGTTCATATAGATTTGGTTTTCCCAATTTTACACGG
CAAAAACGGAGAGGATGGCACACTTCAAGGAATGTTTGAACTTTCGGGTATTCCTGTGATCGGCTGCAATACGCTTGCTT
CGGCTCTCTGTATGGATAAGGACAGAGCGCACAAGCTCGTAAGCCTTGCCGGAGTAAAAGTTCCGAAATCGGTAACTTTC
AAACGCTCTGAAAAGAATACGGCTTTGAAAAAAATCGAAACAGAGCTTTCCTATCCGCTTTTCGTAAAACCGGTTCGTGC
AGGCTCGTCTTTTGGTATTACAAAAGTAACTGAGCAAGCAGAAATAAATACCGCCATAGAATCAGCCTTTGAACACGATA
CAGAAGTCATCGTTGAAGAAGCAATAGGTGGATTTGAGGTAGGCTGCGCCATACTCGGTATCGACAACCTGACGGTTAGA
CGAATAGATGAAATTGAACTGTCAAACGGTTTCTTTGACTATACAGAAAAATATACCTTAAAAACTTCAAAAATCCATAT
GCCTGCAAGACTTTCTCCAAAAGAAGAAAAACGGGTACAGGAAACAGCGGTGGCGATATATAAGGCTTTGGGCTGTTCCG
GCTTTGCGAGGGTAGATATGTTTTATACACCTTCCAATGAGATCATTTTTAATGAAGTGAATACCATACCGGGACTTACC
TCCCACAGTCGCTATCCAAATATGATGAAAGGTATCGGTCTGTCCTTTGCGGATATGTTGGACAAGCTGATAAGTCTGTA
TGTGGAATGA

Protein sequence :
MQKKKIAVIFGGNSTEYEVSLQSAFSVFENINHDKYDIIPIGITRNGDWYHYKGRYENIANNTWSGDRDNLYPVTVSVSH
SQKGIWEFDEDQYTAVHIDLVFPILHGKNGEDGTLQGMFELSGIPVIGCNTLASALCMDKDRAHKLVSLAGVKVPKSVTF
KRSEKNTALKKIETELSYPLFVKPVRAGSSFGITKVTEQAEINTAIESAFEHDTEVIVEEAIGGFEVGCAILGIDNLTVR
RIDEIELSNGFFDYTEKYTLKTSKIHMPARLSPKEEKRVQETAVAIYKALGCSGFARVDMFYTPSNEIIFNEVNTIPGLT
SHSRYPNMMKGIGLSFADMLDKLISLYVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanB NP_815951.1 D-alanine--D-lactate ligase Not tested Not named Protein 5e-63 44
vanB YP_008394259.1 Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase Not tested Not named Protein 8e-63 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase U00456.gene.p01 Protein 2e-63 44
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase U35369.1.gene6.p01 Protein 2e-63 44
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AE016830.1.gene2250. Protein 2e-63 44
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AF310956.2.orf5.gene Protein 5e-64 44
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase L29638.gene.p01 Protein 3e-63 44
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AY145441.gene.p01 Protein 5e-64 43
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AF277571.gene.p01 Protein 7e-61 43
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AY489045.gene.p01 Protein 9e-61 43
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AF162694.gene.p01 Protein 2e-66 43
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase NC_005054.2598280.p0 Protein 1e-61 42
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase NC_014475.1.orf3.gen Protein 1e-61 42
RBR_17480 YP_007781707.1 D-alanine--D-alanine ligase AF130997.1.orf4.gene Protein 5e-57 41