Gene Information

Name : RO1_16840 (RO1_16840)
Accession : YP_007778044.1
Strain : Roseburia intestinalis XB6B4
Genome accession: NC_021012
Putative virulence/resistance : Unknown
Product : GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1682126 - 1683745 bp
Length : 1620 bp
Strand : +
Note : -

DNA sequence :
ATGAACAGATTGCAGGCAACGAAAACATCAGGAGGAAGAAGATCAATGGATCATGAGAAAGTAATTGTCATTGATTTTGG
CGGTCAGTACAACCAGCTGGTTGCGAGACGTGTCAGAGAATGCAATGTTTACTGTGAAATATATTCCTACAAGACGGATA
TCGCGCAGATCAAGGCAATGAATCCAAAGGGAATCATTCTTACCGGCGGTCCGAACAGCTGCTATGAAGCTGATTCACCG
ACCTGTTCAAAAGAATTATTTGAACTCGGCGTGCCGGTTTTAGGACTCTGCTATGGTGCGCAGTTGATGATGCACGTACT
TGGAGGAAAGGTGGAAAAGGCACCTGTCCGTGAATATGGTAAGACCGAGGTTATGGTCGATACGTCATCACCGTTATTTA
CCGGCGTATCAGAAAATACGATCTGCTGGATGAGTCATTTCGATTATATTTCAAAGGCTGCACCGGGATTTAACATCGTT
GCACATACGGCGGATTGTCCGGTTGCCGCAGCAGAGAACCAGGAGAAAGGATTATTTGCAATCCAGTTCCACCCGGAAGT
ACTTCACACACAGGAAGGCACAAAGATGCTTCACAACTTTGTACGCGGCATCTGCGGTTGTGAGGGAACCTGGAGAATGG
ATTCTTTTGTTGAGAATACGGTAAAAGAGATCCGTGAAAAAGTCGGTAACGGAAAAGTACTGCTTGCCTTATCCGGCGGT
GTGGATTCTTCCGTTGCAGCAGGTCTGTTATCCCGTGCAATCGGAAAACAGCTTACCTGTGTGTTCGTAGACCATGGTCT
TCTCCGCAAAAATGAGGGCGACGAGGTCGAAGAAGTATTCGGACCAAACGGACAGTTTGATCTGAACTTTATCCGTGTCA
ACGCACAGGACCGTTATTATGGAAAATTAGCCGGTGTGACAGAGCCGGAGCATAAACGTAAGATCATTGGTGAGGAGTTC
ATCCGTGTCTTTGAGGAAGAGGCAAAGAAGATCGGTGCCGTTGATTTCCTTGCACAGGGAACCATTTATCCGGATGTCGT
TGAGAGCGGACTTGGCGGAGAGTCAGCCGTCATCAAATCCCACCACAACGTAGGCGGTCTGCCGGACTTCGTTGATTTCA
AAGAAATCATTGAGCCGCTCCGCAACCTTTTCAAGGATGAGGTAAGAAAAGCCGGACTTGAACTTGGCATCCCGGAAAAA
CTTGTTTTCCGTCAGCCATTCCCGGGACCGGGACTCGGTATCCGTATCATCGGAGAAGTAAATGCCGAGAAAGTCAAGAT
CGTGCAGGATGCCGATGCCATCTACCGCGAGGAAGTGGACAAGGCAGTGGAGGAATACACCAAAGCAAACGGAAAGGCAC
CATCCTGGATGCCGAACCAGTACTTTGCAGCACTGACCAACATGCGTTCCGTCGGTGTCATGGGCGACGAGCGCACCTAC
GACTATGCCGTGGCACTGCGTGCTGTTAATACGGTCGATTTCATGACCGCTGAGTCAGCAGAGATCCCGTTTGAGGTGCT
CCAGAGAGTTATGAGCAGAATTATTAATGAGGTGAAGGGCGTCAATCGGGTAATGTATGATTTGACGAGTAAGCCACCGG
GAACGATTGAGTTTGAATAA

Protein sequence :
MNRLQATKTSGGRRSMDHEKVIVIDFGGQYNQLVARRVRECNVYCEIYSYKTDIAQIKAMNPKGIILTGGPNSCYEADSP
TCSKELFELGVPVLGLCYGAQLMMHVLGGKVEKAPVREYGKTEVMVDTSSPLFTGVSENTICWMSHFDYISKAAPGFNIV
AHTADCPVAAAENQEKGLFAIQFHPEVLHTQEGTKMLHNFVRGICGCEGTWRMDSFVENTVKEIREKVGNGKVLLALSGG
VDSSVAAGLLSRAIGKQLTCVFVDHGLLRKNEGDEVEEVFGPNGQFDLNFIRVNAQDRYYGKLAGVTEPEHKRKIIGEEF
IRVFEEEAKKIGAVDFLAQGTIYPDVVESGLGGESAVIKSHHNVGGLPDFVDFKEIIEPLRNLFKDEVRKAGLELGIPEK
LVFRQPFPGPGLGIRIIGEVNAEKVKIVQDADAIYREEVDKAVEEYTKANGKAPSWMPNQYFAALTNMRSVGVMGDERTY
DYAVALRAVNTVDFMTAESAEIPFEVLQRVMSRIINEVKGVNRVMYDLTSKPPGTIEFE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-141 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-141 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-141 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-119 49