Gene Information

Name : merA2 (OAN307_c31790)
Accession : YP_007705342.1
Strain : Octadecabacter antarcticus 307
Genome accession: NC_020911
Putative virulence/resistance : Resistance
Product : mercuric reductase MerA
Function : -
COG functional category : -
COG ID : -
EC number : 1.16.1.1
Position : 3148917 - 3150350 bp
Length : 1434 bp
Strand : -
Note : alternative name(s): Hg(II) reductase

DNA sequence :
ATGCTTGATTTACAAACGCCAGACTTGGTGGATGCCGATACTTTTGACCTTGCTGTTATTGGTGCCGGCTCTGCTGGGTT
TTCCGCAGCAATTACCGCTGCCGAAGACGGAGCACGGGTTGCGCTTATTGGATATGGAACCATTGGCGGCACTTGCGTCA
ATGTCGGATGTGTCCCATCCAAAGTGATGATCCGTGCAGTGGGAACGCTGCACTCAGCCAAGGGTGCGGCCCGATTTGAT
GGAGTGGAAGCCACCGCACAAGTGACCGACTGGGTGGCGTTGGTCGCCCAAAAGCGAGCCTTGGTGGATGATCTACGCGC
AGCAAAATACGTTGATGTTTTGCCAAACTATGAGGGCGTGTCCTACATTGAAGGCCAGGCAAGTTTTGTGAAAGATGGTT
CACTGCATGTTGGTGACCGCACCATACGTGCCCCTAAAATCATCATTGCAACAGGATCGTCGCCACATATCCCCAATATC
CCCGGACTGAGTGAAGTTGGTTGGCTGGACAGCACCTCTGCTCTTGAACAAAAAAAGCTCCCAAAATCGTTAATGGTGAT
GGGCGGCGGCTATATCGGGGTTGAAATCGCCCAGATATTCGCGCAGGCAGGTGTCAAAGTTACCATCGTGACGCGCCGTG
GACTGCTGCCCGAAGCCGAGCCGGAAGTCAGTGATGCCCTGACGAAAGCCTTCACCAATGAAGGCATCAAAGTCCTTGAT
GGCCTGTCCTATGACAGTTTCGAGGCGTCAGGCGAGGGTGTTATTCTTCACGCAGCACGTAATGGCGTAGCGGTCAGGAT
AGAAGCTGAAAAACTCTTGCTGGCCACGGGTCGTGTCCCAAACACTGGCTCATTGGCGCTCGACATTGCCGGTATCGACA
CGAATGCGCGCGGCGGAATTGTAATCGACCCGCAGATGCGAAGCACGCGCGACGGGGTTTATGCGACGGGGGATGTGACC
GGAACCGATCAGTTCGTCTACATGGCGGCATACGGTGCAAAGCTTGCCGCTAAAAACGCGATGAATGGAAACACACTAGT
CTATGATAACAGCATCATGCCTGCCGTGGTCTTTTCCGATCCGCAAGTGGCGAGTGTTGGTCTTACCGAGGCCCAAGCCA
AGTCTGCTGGACATGATGTAGTGACTTCGGTTCTGGGTCTTGAGCACGTGCCACGGGCCTTGGCGGCGCGTGATACACGG
GGTCTAATCAAGCTGATTGCGGACAAGCAGAGCAAGAAGCTCCTTGGTGCGCATATCATCGCTCCAGAAGGCGCAGATAG
CATTCAGACGGTGGCAATGGCGCTTAAAATGGGTATGACCTACAACGACTCGGGTGCGATGATTTTTCCGTATCTCACAA
CAGTAGAAGGACTAAAACTGGCTGCGCAGACGTTCGAGAAGGATGTCACAAAGCTGTCGTGTTGTGCGGGGTAA

Protein sequence :
MLDLQTPDLVDADTFDLAVIGAGSAGFSAAITAAEDGARVALIGYGTIGGTCVNVGCVPSKVMIRAVGTLHSAKGAARFD
GVEATAQVTDWVALVAQKRALVDDLRAAKYVDVLPNYEGVSYIEGQASFVKDGSLHVGDRTIRAPKIIIATGSSPHIPNI
PGLSEVGWLDSTSALEQKKLPKSLMVMGGGYIGVEIAQIFAQAGVKVTIVTRRGLLPEAEPEVSDALTKAFTNEGIKVLD
GLSYDSFEASGEGVILHAARNGVAVRIEAEKLLLATGRVPNTGSLALDIAGIDTNARGGIVIDPQMRSTRDGVYATGDVT
GTDQFVYMAAYGAKLAAKNAMNGNTLVYDNSIMPAVVFSDPQVASVGLTEAQAKSAGHDVVTSVLGLEHVPRALAARDTR
GLIKLIADKQSKKLLGAHIIAPEGADSIQTVAMALKMGMTYNDSGAMIFPYLTTVEGLKLAAQTFEKDVTKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 3e-85 47
merA AGK07021.1 MerA Not tested SGI1 Protein 3e-85 47
merA AGK07079.1 MerA Not tested SGI1 Protein 3e-85 47
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 5e-83 47
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-83 46
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-83 46
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 5e-83 46
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 6e-81 46
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 1e-80 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-82 45
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-87 44
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-87 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA2 YP_007705342.1 mercuric reductase MerA BAC0653 Protein 6e-84 47
merA2 YP_007705342.1 mercuric reductase MerA BAC0652 Protein 1e-83 46
merA2 YP_007705342.1 mercuric reductase MerA BAC0650 Protein 1e-78 45
merA2 YP_007705342.1 mercuric reductase MerA BAC0651 Protein 2e-87 44
merA2 YP_007705342.1 mercuric reductase MerA BAC0649 Protein 2e-70 42