Gene Information

Name : merA1 (OAN307_c17630)
Accession : YP_007704062.1
Strain : Octadecabacter antarcticus 307
Genome accession: NC_020911
Putative virulence/resistance : Resistance
Product : mercuric reductase MerA
Function : -
COG functional category : -
COG ID : -
EC number : 1.16.1.1
Position : 1741641 - 1743053 bp
Length : 1413 bp
Strand : -
Note : alternative name(s): Hg(II) reductase

DNA sequence :
ATGAACGACAGCTATGGCAATTTTGACCTTGCCGTGATCGGTGCTGGCTCTGCCGGGTTTTCCGCAGCGATTACCGCAGC
CGAAGACGGCGCACAGGTTGCTCTGATTGGGTGCGGAACCATTGGAGGCACTTGCGTCAATGTTGGATGCGTCCCGTCCA
AGGCAATGATCCGTGCAGTGGAAACGCTGCACTCAGCCAAGGGCGCGGCCCGATTTGATGGTGTGGAAGCAACCGCACAA
GTGACGGATTGGGCGGCGTTGGTCGCGCAGAAACAAGCCTTGGTGGATGATCTACGCGCGGCGAAATACGTTGATGTTTT
GCCAAACTATAAGGGCGTCAATTACATCGAAGGTCAGGCAAGTTTTGCGAAAGATGGTTCACTGCATGTTGGAGACCGCA
CCATCCGCGCACCTAAAATCATCATTGCAACAGGATCGTCCCCGCATGTCCCAAATATCCCCGGATTGAGTGAAATCGAT
TGGCTAGACAGCACCTCAGCTCTTAAACAAAAGCAGCTCCCAAAATCCCTGATGGTGATGGGTGGTGGATATATCGGGGT
TGAACTCGCCCAGATATTCGCACGAGCAGGCGTCGAAGTTACCATCGTAACGCGCAGTGGACTGCTGCCCGAAGCTGAAC
CAGAAGTCAGCGAAGCCCTGACGAAAGCGTTTGCCGATGAGGGCATTAAAGTGCTGGACGGTTTGTCCTATGACAAATTT
GAAGCGTCAGACGAGGGTGTCACATTGCTCGCCGCCCATAACGGCGTAGCGATCAGGATCGAAGCCGAAAAGTTGTTGCT
GGCAACCGGTCGTGTCCCGAACACTGGCTCTTTGGCGCTCGATATCGCCGGTATCGACACGAATGCACGCGGCGGAATTG
TTATCGACGCGCAGATGCGCAGCACGCGCGACGGGGTTTATGCGACAGGCGATGTGACTGGGATGGATCAATTCGTCTAT
ATGGCTGCTTACGGTGCAAAGCTTGCCGCGAAAAACGCGATGAACGGTAACACTTTGGCCTATGATAATAGCGTCATGCC
TGCCGTGGTCTTCTCTGATCCGCAGGTGGCCAGTGTAGGTCTGACCGAGGCACAAGCCAAGTCTGCCGGACACGAGGTGG
TGACTTCGGTTCTGGGTCTTGAACACGTGCCACGGGCCTTGGCAGCACGTGATACACGCGGTTTGATCAAGTTGATTGCC
GACAAGCAAAGCAAGAAGCTTTTGGGAGCGCATATCATCGCACCAGAAGGTGCTGATAGCATCCAGACAGCAGCGATGGC
CCTCAAGATGGGCATGACCTACGACGATCTGGGCGCGATGATTTTTCCGTATCTTACAACCGTAGAAGGGCTGAAGCTTG
CCGCGCAAACGTTCGAGAAGGATGTTTCTAAACTGTCGTGCTGCGCGGGGTAG

Protein sequence :
MNDSYGNFDLAVIGAGSAGFSAAITAAEDGAQVALIGCGTIGGTCVNVGCVPSKAMIRAVETLHSAKGAARFDGVEATAQ
VTDWAALVAQKQALVDDLRAAKYVDVLPNYKGVNYIEGQASFAKDGSLHVGDRTIRAPKIIIATGSSPHVPNIPGLSEID
WLDSTSALKQKQLPKSLMVMGGGYIGVELAQIFARAGVEVTIVTRSGLLPEAEPEVSEALTKAFADEGIKVLDGLSYDKF
EASDEGVTLLAAHNGVAIRIEAEKLLLATGRVPNTGSLALDIAGIDTNARGGIVIDAQMRSTRDGVYATGDVTGMDQFVY
MAAYGAKLAAKNAMNGNTLAYDNSVMPAVVFSDPQVASVGLTEAQAKSAGHEVVTSVLGLEHVPRALAARDTRGLIKLIA
DKQSKKLLGAHIIAPEGADSIQTAAMALKMGMTYDDLGAMIFPYLTTVEGLKLAAQTFEKDVSKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-87 49
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-87 49
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-87 49
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 4e-84 48
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-84 48
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-84 48
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-84 48
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-84 48
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-84 48
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-90 46
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-90 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-83 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA1 YP_007704062.1 mercuric reductase MerA BAC0653 Protein 2e-86 49
merA1 YP_007704062.1 mercuric reductase MerA BAC0652 Protein 7e-87 49
merA1 YP_007704062.1 mercuric reductase MerA BAC0651 Protein 1e-90 46
merA1 YP_007704062.1 mercuric reductase MerA BAC0650 Protein 3e-80 45