Gene Information

Name : merA (OA238_c45600)
Accession : YP_007701883.1
Strain : Octadecabacter arcticus 238
Genome accession: NC_020908
Putative virulence/resistance : Resistance
Product : mercury reductase MerA
Function : -
COG functional category : -
COG ID : -
EC number : 1.16.1.1
Position : 4865303 - 4866736 bp
Length : 1434 bp
Strand : +
Note : alternative name(s): Hg(II) reductase

DNA sequence :
ATGCTTAATTTACTGAACCCAAAAGCTGGCAATACCGATACATTTGATCTTGCAGTTATTGGTGCTGGTTCTGCTGGCTT
TTCCGCTGCTATTACTGCTGCTGAAGCCGGTGTGAGGGTTGCTCTCATTGGGTATGGAACCATTGGCGGCACTTGCGTCA
ATGTCGGGTGCATCCCCTCCAAAGCGATGATCCGTGCTGTGGAAACACTGCACTCGGCCAAAGTGGCTGATCGGTTTGAC
GGCGTGGAAGCTATGGCAAAAGTGACGGACTGGGCGGCAATGGTGGCCCAAAAGCAAGCCTTGGTCGATGATCTGCGCGC
GGCAAAATACGTTGATGTTTTGCCAAACTATGAGGGCGTCACTTACATTGAAGGTCAGGCAAATTTCACCGAAGATGGCT
CCTTAGAGGTCGGTAACCGCACCATCCGCGCGCCAAAAGTCATCATTGCAACGGGTTCGTCCCCGCATGTCCCAGATATC
CCTGGACTGGACGACATCGATTTTCTGGACAGCACCTCGGCACTTGAACAGGCGCAACTCCCGAAATCACTGATGGTGAT
GGGTGGCGGATATATTGGCGTCGAGATTGCTCAGATATTCGCCCGAGCTGGCGTCAAAGTGACCATCGTTACGCGTCGTG
GTCTGTTGCCGGAGGCAGAACCGGAAGTCAGCGAAGCCCTGACAAAAGCCTTTGCCGATGAGGGCATCAAAGTGCTGGAC
GGGCTGGCATATGACAGGTTTGAAAAGTCTGGCGAGGGCGTGACCCTGCACGCCGCACATAATGGCGTTGCCGTCAGGAT
CGAAGCCGAAAAGCTCTTGCTGGCGACGGATCGAACGCCGAATACGAACTCATTGTCGCTCGATATCGTTGGTATCGACA
CGAATGCAAGGGGCGGAATTATTATCGACCCGCAGATGCGCAGCACGCGGGACGGCGTTTATGCGACAGGCGATGTGACC
GGGGCTGATCAGTTCGTTTATATGGCTGCCTATGGCGCGAAGCTCGCGGCCAAGAACGCGATGAATGGAAACGCCTTGAG
CTATGACAATAGCGTCATGCCTGCCGTGGTCTTCTCTGACCCGCATGTGGCCAGTGTCGGCCTCACTGAGGCGCAGGCAA
AGTCTGCTGGTCATGAGGTGGTGACATCGGTTCTAGGTCTGGAACATGTGCCTCGCGCCTTGGCCGCACGTGATACACGC
GGTTTGATCAAGCTGATTGCGGACAAGGACAGCAAGAAACTCTTGGGCGCGCATATTATAGCTCCAGAAGGCGCGGACAG
CATCCAGACGGCAGCAATGGCGCTCAAGATGGGGATGACTTACGATGATTTGGGCGCGATGATCTTTCCTTACCTCACAA
CTGTCGAGGGGTTGAAACTGGCCGCGCAAACATTCGAAAAGGATGTCGCAAAGCTATCCTGCTGCGCGGGATAG

Protein sequence :
MLNLLNPKAGNTDTFDLAVIGAGSAGFSAAITAAEAGVRVALIGYGTIGGTCVNVGCIPSKAMIRAVETLHSAKVADRFD
GVEAMAKVTDWAAMVAQKQALVDDLRAAKYVDVLPNYEGVTYIEGQANFTEDGSLEVGNRTIRAPKVIIATGSSPHVPDI
PGLDDIDFLDSTSALEQAQLPKSLMVMGGGYIGVEIAQIFARAGVKVTIVTRRGLLPEAEPEVSEALTKAFADEGIKVLD
GLAYDRFEKSGEGVTLHAAHNGVAVRIEAEKLLLATDRTPNTNSLSLDIVGIDTNARGGIIIDPQMRSTRDGVYATGDVT
GADQFVYMAAYGAKLAAKNAMNGNALSYDNSVMPAVVFSDPHVASVGLTEAQAKSAGHEVVTSVLGLEHVPRALAARDTR
GLIKLIADKDSKKLLGAHIIAPEGADSIQTAAMALKMGMTYDDLGAMIFPYLTTVEGLKLAAQTFEKDVAKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 1e-83 47
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 9e-84 47
merA AFG30120.1 MerA Not tested PAGI-2 Protein 9e-84 47
merA ABQ57371.1 MerA Not tested SGI1 Protein 4e-87 47
merA AGK07021.1 MerA Not tested SGI1 Protein 4e-87 47
merA AGK07079.1 MerA Not tested SGI1 Protein 4e-87 47
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 8e-84 47
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 5e-85 46
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 5e-83 46
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-83 46
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-87 42
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-87 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_007701883.1 mercury reductase MerA BAC0653 Protein 7e-85 47
merA YP_007701883.1 mercury reductase MerA BAC0652 Protein 1e-85 46
merA YP_007701883.1 mercury reductase MerA BAC0650 Protein 7e-79 43
merA YP_007701883.1 mercury reductase MerA BAC0651 Protein 9e-88 42