Gene Information

Name : D648_15990 (D648_15990)
Accession : YP_007669111.1
Strain : Mannheimia haemolytica USDA-ARS-USMARC-185
Genome accession: NC_020834
Putative virulence/resistance : Unknown
Product : type I restriction enzyme HindVIIP R protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1619354 - 1622512 bp
Length : 3159 bp
Strand : +
Note : Type I site-specific restriction-modification system, R (restriction) subunit and helicases COG0610; type I restriction enzyme HindVIIP R protein of Proteobacteria UniRef RepID=T1RH_HAEIN

DNA sequence :
ATGATTACCATCAACGAAAACACCATTGAACAATCCGCCATTGCAACTTTGCAAAGCTTGGGCTGGGACTACACCTACGG
CAAAAAAATTTTGGCAGGTTTAGAACACGAATGGCGGGAGCGAACCGCTGAGGTGATTTTAAAGCCGCTTTTGGCGCAAG
CGATTGCAAAATTCAACCCGAATTTGCCCGCTTGTGAGGTGGAAAATGTGGTGGCACAGGTGTGCCGTGCCGACAGTGGC
GATTTGGCGGAGCGTAATCGTCAGGCTTATGATTGGCTAAGAAATGGGGTCAAAATCACTTATCAGTTGTACGGTGAGCA
GGTGTCTGATGTGGTGCAGCTGATTGATTTTCAGCGTCCAGAAAATAACGATTTTCGCATTGTCAATCAGCTGGATATTA
GCGGCAAAAAAGGCAAACGCATTCCGGATTTGATTGGCTTTGTTAATGGCTTGCCGCTGGTGGTGTTTGAGCTGAAAAAT
CCGCTCAAAGAAAATGCCGACATTGGCAAGGCGTTTGCCCAACTGCAAACCTATAAAGATGAAATTTCTGATTTGTTTGT
GTTTAATCAGGCACTCGTGATTTCAGACGGCATTGTCGCCCGCATCGGTTCGCTGACCGCTGATTTCGACCGTTTTACCC
CTTGGCGTGTGGTTGATGAAAAAAATCAGAGCAAACGCATTGTGTTTGAAGATGAACTCACCGCCCTGCTGCAAGGCGTG
ATGACACCCAAAAATCTCTTGGATTATGTGCAGAATTTTGTGGTGTTTGAACGGGACGGCAAAAACCGCTTAATTAAGAA
AATCGGAGCATATCATCAGTTTTATGGCGTGAATGAAGCGGTGGATTGCACCTTGCTTGCCGCCACAGGCAACCGCAAAA
TCGGCGTGTTTTGGCATACGCAAGGTTCGGGCAAATCGCTTTCGATGCTGTTTTATGCAGGTAAAGTATTAAGCCAAAGC
AGCCTGAAAAATCCAACTTTGGTGTTGGTAACCGACCGCAACGATTTGGACGGTCAGCTTTACGCCACTTTTTGCGGTGG
CGAGGCACTGCTCAAACAAACGCCAATCCAAGCCGATGGGCGAGACGAACTCCGCTCTGCCCTTGCCAGTCGTTCGGCAG
GCGGTGTGATTTTTACCACCATTCAAAAATTCGGCTTAATGGAGGGTGAGCTTGCCCACCCTGTATTAAACGAGCGGGAA
AACATCATTGTGATTACCGATGAAGCACACCGCTCACAATATGGTTTTAGCCAAAAAATCAACCACAAAGGCGAGTATCG
TGAGGGTTATGCCAAGCATTTACGCAGTGCATTGCCGAATGCCTCTTTTATTGGCTTTACTGGCACACCGATTGAACTTG
ATGACAAAGACACCCAAGAAGTCTTCGGTAAATATGTCTCGATTTATGATTTTGAAGATGCGGTGGAAGATGGGGCAACC
GTGCCGATTATTTATGAGCCACGCCAAATCAGCTTAGGCGAAAGTGGCGAGTTTTCCAAAGTGATGGAAGAGGCACAACA
ACTGATTGATGACGATGAAAACAGCTATAACTTCCGCCTGCGTGAAAAACTGCACAGCGTGGATAGCCGTTTGCAAAAAA
TGGCGGAAGATATTATTGCCCATTACGATGAGCGTACCAAACAGCAAGACGGCAAGGCGATGGTTGTGGTGATGAGCCGT
GCCATTTGCGTGAAATTGTACGAAAAAATCACCGCACTTCGTCCAGAATGGCACTCAAACGATGTGCTTCAAGGCAGCAT
TAAAATTGTGATGACAAGTAATGCCAGCGACCCTGCCGAGTGGCAAAAACACAATCAGGATAAGAAAACCTTAGAAAAAC
GCTTTAAAGACCCAGACGATCCGCTCAACATCGTGATTGTGCGGGATATGTGGCTGACAGGCTTTGATGCGCCCTGCTGT
AACACAATGTACATTGATAAACCAATGAGCGGACACAACCTGATGCAGGCAATCGCTCGGGTAAATCGGGTATTTCGCAA
CAAAAGCCGTGAAAATGGCGGCTTGATTGTGGATTATGTGGGCTTGACCGATGAGCTGGAAAAAGCGATGAAGCAGTACA
CCAACGCAGGCGGTAAAGAAAAGCCGGTGCGGGACATTTCAGCGGTGCTGGAAAAAATGGTGGAACATATCACGGTCATT
CGTGGGCAATTTGCCACACCGATTGACGGACAAGCGGTTGATATTGCCAAAATGTTGCAAATCAGCGAACCGCCTAAACT
GCTCAATGCGATTTTGACATCAGCCAACCATATTCTTGCCCTAGACCGCATTCAGCCACCTGATAACACTGCCAAAGACA
AAACCCCACGCAAAAACGCCTTTTTGCAATCGGTACGCTTGGCGAAAAAAGGTTATGCTTTGTGTGGGGCATTAAAAGCA
GTTGAACCCTATAAACAGGAACTGGCGTTTTATGATGCAGTGCGTGCCACCATTATCAAAAACAGCACCGCTCCTCGCAA
TTCTTCGAGCGAAAATGACCGCTTGTTGCAGCTTACCGCCTTGATGAATCGTGCGGTACAGTCGGATGGTGTGGTGGATT
TATTTGATTTGCTGAAAAAAGACCGCCCAAACATCAACCTGCTTTCTGATGAGTTTTTGGAAACAGTAAAAAACAGCCCA
ACCAAAGATTTGTGGCTATCAGCAATGGAGCGTTATCTTGCCTCACAACTGCGAGAGCAAAGCGGTGCCAATCTTGCCAC
AAAAAAAGCATTTGAACAGAAACTCAAAGAGGCGATGAACCAATACCACAACCACAATTTAAGCGTATTGGAAATTTTAG
AAGAGCTGATCGCCCTCGCCAAAGAGTTTGAAGCCCGCCAAAAACGAGGGGAAGCGTTGGGACTAAGCCCTGCGGAAATG
GCGTTTTATGATGCTTTGGCACGTAATGAAAGTGCGGTGCGGGAAATGGGCGATGAGGTATTGATGAAACTTGCCAAAGA
CATTACCGATAAATTACGCAAATCGGTCACCGTAGATTGGCAATATAAAGACTCGGTTCGTGCCAAAATGCGAACCTTAA
TCCGCATTGCTCTGCGTACCTATAAATACCCGCCCGATTTACAGGCGGAAGCGATTGAGTTTGTGTTGCAACAAGCGGAA
GAGATCGCCGGAGAGTTCGCTATCACCGAAACGGCGTAA

Protein sequence :
MITINENTIEQSAIATLQSLGWDYTYGKKILAGLEHEWRERTAEVILKPLLAQAIAKFNPNLPACEVENVVAQVCRADSG
DLAERNRQAYDWLRNGVKITYQLYGEQVSDVVQLIDFQRPENNDFRIVNQLDISGKKGKRIPDLIGFVNGLPLVVFELKN
PLKENADIGKAFAQLQTYKDEISDLFVFNQALVISDGIVARIGSLTADFDRFTPWRVVDEKNQSKRIVFEDELTALLQGV
MTPKNLLDYVQNFVVFERDGKNRLIKKIGAYHQFYGVNEAVDCTLLAATGNRKIGVFWHTQGSGKSLSMLFYAGKVLSQS
SLKNPTLVLVTDRNDLDGQLYATFCGGEALLKQTPIQADGRDELRSALASRSAGGVIFTTIQKFGLMEGELAHPVLNERE
NIIVITDEAHRSQYGFSQKINHKGEYREGYAKHLRSALPNASFIGFTGTPIELDDKDTQEVFGKYVSIYDFEDAVEDGAT
VPIIYEPRQISLGESGEFSKVMEEAQQLIDDDENSYNFRLREKLHSVDSRLQKMAEDIIAHYDERTKQQDGKAMVVVMSR
AICVKLYEKITALRPEWHSNDVLQGSIKIVMTSNASDPAEWQKHNQDKKTLEKRFKDPDDPLNIVIVRDMWLTGFDAPCC
NTMYIDKPMSGHNLMQAIARVNRVFRNKSRENGGLIVDYVGLTDELEKAMKQYTNAGGKEKPVRDISAVLEKMVEHITVI
RGQFATPIDGQAVDIAKMLQISEPPKLLNAILTSANHILALDRIQPPDNTAKDKTPRKNAFLQSVRLAKKGYALCGALKA
VEPYKQELAFYDAVRATIIKNSTAPRNSSSENDRLLQLTALMNRAVQSDGVVDLFDLLKKDRPNINLLSDEFLETVKNSP
TKDLWLSAMERYLASQLREQSGANLATKKAFEQKLKEAMNQYHNHNLSVLEILEELIALAKEFEARQKRGEALGLSPAEM
AFYDALARNESAVREMGDEVLMKLAKDITDKLRKSVTVDWQYKDSVRAKMRTLIRIALRTYKYPPDLQAEAIEFVLQQAE
EIAGEFAITETA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 48
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 42
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 41
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 41