Gene Information

Name : D650_16670 (D650_16670)
Accession : YP_007666444.1
Strain : Mannheimia haemolytica USDA-ARS-USMARC-183
Genome accession: NC_020833
Putative virulence/resistance : Unknown
Product : DNA topoisomerase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1606437 - 1608488 bp
Length : 2052 bp
Strand : -
Note : DNA topoisomerase III PRK07726; DNA topoisomerase of Proteobacteria UniRef RepID=Q4QPE8_HAEI8

DNA sequence :
ATGAAACTGTTTATTTGTGAAAAGCCCTCTCAAGCCCGAGATCTTGCAAGTGTATTAGGTGCTACATCGAAAGGGGATGG
ACTATTGGCAACTAATGATAAGTCTATTATTGTAACTTGGGGATTTGGTCATCTTGTTGAGCAATACCAACCCGAGGATT
ATGATGAAGTTTGGAAACGCTGGGCATTTGAAACATTGCCGATCATTCCTGCTCAATGGAAAATGGCTCCTAAAAAAGAG
TCCAAGAAACAATACAATGTAGTCATCGGATTAATTAAGAAAGCCTCTTTGGTTGTGATTGCAACCGATGCAGACAGAGA
AGGTGAAATGATTGCTCGTGAACTGTTAGATTTAGCCGGATACCGAGGACAAATACAGCGTTGCTGGCTATCAGCTCTCG
ATGATGCCAGTATCCGAAAAGCTCTCCAAACACTCAAATCAGGTAAAGAAACCGAGGCACTTTACTACGCTGGTATGGGA
CGTAGCCGCTCGGACTGGCTGATTGGAATGAACTTCTCCCGTCTATTTACCTTAATGGCCCAAGCAAAAGGCTATTCCGG
TAAGCCATTAAGCGTTGGTCGAGTGCAAAGCCCAACACTAGCTCTTGTGGTCAATCGAGACAGAGAGATTGCAAATTTCG
TGCCTAAAGCTCATTACTCCTTAGCAGTTCAATTAGCAACAGCGTCTGATGAAACCTTTGTTGCCGGGCTTTCAATACCT
GAACAGTATTTAGATGAATCAGGGCTTTGCCTTGATAGTCGGGTCATACAACAAGCTGAAGCTCAAATTAAACAAGTAGG
CATAGCCAAAGTGATAACGGTTGAAACCAAACGAGAGAAAAAGGCACCGCCGTTGCTTTATGCATTAAGTGATTTACAAG
GGGAATGTAACCGCTTGTTTGGTTTTGGGGCTCAACAAGTACTTGATATTGCTCAATCACTTTATGAGGAGCATAAAATT
ACTACTTATCCCCGTACCGATTGCGGCTATCTACCTGAATCTCAGCTTACTGAAGTACCGATGGTAATTCGTTCATTAGT
CGCCGCTGATTCAGAGTTACAAACTCTATTGCCTCGATTAAATCTACAACAAAAAAGTCGGGCTTGGGATGATAAAAAAA
TTACTGCTCACCACGGTATTATCCCCACTATCAAAAAAGCAGATTTAAGCAAGTTAAGTGAGGAGGAGATGAAGGTCTAT
GATCTCATTCGCCGTCGCTATCTCGCTCAATTCTTACCGCACTTAGAAACAGATAAAACTATAGCCACCTTGCAGTCCTC
TGGACACACTCTGATTGCTAGAGGAAATGTGATCGTTTCTCAAGGTTGGCGTATCCTGTTTGGTAAAAATGCAGATGAAG
ATGTTGGTAGTGATGATGAGAAACAAGGCTTACCTGCATTGACGGCAAATCAGCAATGCCGTGTTACACATTCAGAAGTC
CGGACATTACAAACCAAACCACCGGCACACTATACTGAAGGAACACTACTCGAAGCAATGAAAAATGCAGCTCGCTTTGT
GACTGATCCAAGACTTAAACAACGGTTGCGTGAAACGGAGGGATTGGGTACAGAGGCAACTCGTGCCGGATTGATTCAAG
GGCTCATTGACAAAGGTTTTTTAATTAAGAAGAAAAAATCCCTAATGGCTTCTGCTGAAGCGATTGCCCTTATTGATAGC
CTACCGGATTTATTAAAAAATCCCGGTTTAACGGCTCTTTGGGAACAGGCACTTAATCAAATTGCTGAAGGCAGTATGAC
CCTTGATGACTTTATGCAACGACAAGAAACCTTTGTACGACAACTTATCGGAAATTGTATGCAACAAGGTATGTCATTGG
GTAATATTGAAATTCGAAAATGCCCGGAGTGTGGTAAGCCAATGCGGAAAATCAATCACGCTAAAGGTACATTCTGGGGT
TGTACAGGATATCCGGATTGCCAACATAAAGAAGCAGATAAAAAAGTCAAATCGACTTCAAATAAATCTACCAAGAAAAA
TAGTAGCTTAAATGTGCTAGATCAGCTGAATAAATTAAGAAGCCAGTTATAA

Protein sequence :
MKLFICEKPSQARDLASVLGATSKGDGLLATNDKSIIVTWGFGHLVEQYQPEDYDEVWKRWAFETLPIIPAQWKMAPKKE
SKKQYNVVIGLIKKASLVVIATDADREGEMIARELLDLAGYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMG
RSRSDWLIGMNFSRLFTLMAQAKGYSGKPLSVGRVQSPTLALVVNRDREIANFVPKAHYSLAVQLATASDETFVAGLSIP
EQYLDESGLCLDSRVIQQAEAQIKQVGIAKVITVETKREKKAPPLLYALSDLQGECNRLFGFGAQQVLDIAQSLYEEHKI
TTYPRTDCGYLPESQLTEVPMVIRSLVAADSELQTLLPRLNLQQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVY
DLIRRRYLAQFLPHLETDKTIATLQSSGHTLIARGNVIVSQGWRILFGKNADEDVGSDDEKQGLPALTANQQCRVTHSEV
RTLQTKPPAHYTEGTLLEAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGFLIKKKKSLMASAEAIALIDS
LPDLLKNPGLTALWEQALNQIAEGSMTLDDFMQRQETFVRQLIGNCMQQGMSLGNIEIRKCPECGKPMRKINHAKGTFWG
CTGYPDCQHKEADKKVKSTSNKSTKKNSSLNVLDQLNKLRSQL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 0.0 93
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-165 52
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-159 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 6e-159 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 6e-159 51
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 3e-159 50
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 6e-165 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 1e-148 47