Gene Information

Name : clpB (MED152_01840)
Accession : YP_007670406.1
Strain : Polaribacter sp. MED152
Genome accession: NC_020830
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 392991 - 395597 bp
Length : 2607 bp
Strand : -
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATTTTAATAATTATACAACAAAATCACAAGAGACCATTCAAATGGCGCAACAAATTGCGCAAGGTTATGGTCATAA
TCAAATAGAAAATGAGCATATTTTTAAAGCCTTAATTCAGGTAGATGAAAATGTATTACCTTTTCTATTGAAGAAATTGA
ATATTAATATTGGCTTAATTACACAAATTTTAGATAAGCAATTAGAGAGTTTACCTAAAGTTTCAGGAGCAGAATTAATG
TTATCCAGAGAAGCTGGAACTAGTTTAAATGAAGCATCAATCATTGCTAAAAATATGAAAGATGATTATGTTTCTATAGA
ACACTTAATTTTAGCAATTTTTAAGTCTAAAAGTAAAATTGCCCAGGTTTTAAAAGACCAAGGAGTTCATGAAAAAGATT
TAAAAGCAGCCATTGAAGAGTTAAGAAAAGGAGATAATGTGACTTCGCAAAACCAAGAAGAAACTTACAATTCTTTAAAT
AAATATGCTAAAAATTTGAATCAACTTGCCCAAGAGAACAAGTTAGATCCTGTTATTGGTAGAGATGAAGAAATTAGAAG
ACTTCTTCAAATTTTATCTCGAAGAACTAAGAATAACCCGATTTTAGTTGGTGAACCAGGTACTGGTAAAACAGCTATTG
CAGAAGGTTTAGCTCATAGAATTGTAGATGGTGATGTACCAGAAAACCTAAAAGATAAATTAATTTTTTCTTTAGATATG
GGTGCATTAATTGCTGGTGCAAAATACAAAGGTGAATTTGAAGAGCGTTTAAAAGCAGTAATCAAAGAGGTTACTACTTC
TGAAGGTGACATTGTTTTATTCATTGATGAAATTCATACTTTAGTTGGTGCTGGAGGTGGACAAGGTGCAATGGATGCCG
CAAATATTTTAAAACCAGCTTTAGCTAGAGGAGAATTGCGTGCAATAGGTGCAACTACTTTAGATGAATATCAAAAATAT
TTTGAAAAAGACAAAGCCTTAGAACGTAGATTTCAAAAAGTACAGGTAAATGAGCCAGATACAGAAAGCGCTATTTCTAT
TCTTAGAGGAATTAAAGAAAAGTACGAAACACACCATAAAGTTCGTATTAAAGATGAAGCCATTATTGGTGCTGTAGAAT
TATCTCAAAGATATATTACCAACCGTTTTTTACCAGATAAAGCCATAGATTTAATGGATGAGGCTGCATCAAAATTACGA
ATGGAAATCAACTCTAAACCAGAAGAATTAGATGTATTAGATAGAAAAGTAATGCAGTTAGAGATAGAGATTGAAGCCAT
TAAACGTGAAAAAGACGAAGTAAAATTAAATTCTTTACGTTCGGATTTAGCTAATTTAAAAGAAGAACGTAATGAAATTA
ATGCAAAATGGAAGTCGGAAAAAGAGGTTGTAGATAATATTCAAAATACTAAGGCCGCTATTGAAGATTTTAAATCTGAA
GCTGAAAAAGCAGAACGTGAAGGAGATTATGGAAAAGTTGCTGAAATTAGATATGGTAAAATTAAAAAAGCGCAAGAAGA
TTTAGAAGCTTATCAAAAGGTTTTGCAAGAAAATCAGAATGAAAAATCTTTGATTAAAGAAGAAGTGACTTTAGATGATA
TTGCAGAGGTTGTAGCAAAATGGACAGGAATTCCTGTTACAAAAATGATACAATCTGAACGCGAAAAGCTTTTGAAATTA
GAAGATCAATTACATAAAAGAGTTGTTGGCCAAGAAGAAGCAATTGTGGCCATTTCTGATGCAGTAAGAAGATCTAAAGC
AGGCCTACAAAACCCTAACAAACCTATAGGAAGTTTCTTATTCTTGGGTACAACAGGAGTTGGTAAAACTGAGTTAGCAA
AAGCTTTAGCTGAATATCTTTTTGATGATGAAAATGCGATGACAAGAATAGATATGAGCGAGTATCAAGAGCGTCATTCT
GTGAGTAGATTAGTTGGTGCACCTCCTGGTTATGTTGGTTATGATGAAGGAGGACAATTAACTGAGGCTGTTCGAAGAAA
ACCATACTCTGTAGTGCTTTTAGATGAAATTGAAAAAGCACATCCAGACACTTTTAATGTACTTCTTCAAGTTTTAGACG
AAGGTAGATTAACAGATAATAAAGGTAGAGTTGCAGATTTTAAAAATGCAATAATTATTATGACATCAAATATGGGTAGC
CATATTATACAAGAAAAATTCTCTGATCCTAAAGCAGATTTAGATGCTGTAACTGAATTGGCTAAAATTGAAGTTTTAGG
TTTATTAAAGAAGTCTGTAAGACCTGAATTTTTAAACAGAATAGATGATGTTATTATGTTCACACCTTTAAATAAAGTTG
ATATATTTGAAATTGTAAAATTACAAATAGATCAATTAAAGAAGATGATTGGTAAGCAAGAAATTACTTTAGACGCTACA
GATGAAGCGATTACATATTTAGCTCAAAAAGGATTTCAACCAGAATTTGGTGCTAGACCTGTAAAAAGAGTTATTCAGAA
AGAAGTGTTGAATCAACTTTCTAAAGAAATTTTGGCAGGTAGAATTACAACAGATAGTATTATTTTATTAGATGCTTTTG
ATGATAAATTAGTTTTTAGAAATCAATCTGATTTAGTTGAAAATTAA

Protein sequence :
MNFNNYTTKSQETIQMAQQIAQGYGHNQIENEHIFKALIQVDENVLPFLLKKLNINIGLITQILDKQLESLPKVSGAELM
LSREAGTSLNEASIIAKNMKDDYVSIEHLILAIFKSKSKIAQVLKDQGVHEKDLKAAIEELRKGDNVTSQNQEETYNSLN
KYAKNLNQLAQENKLDPVIGRDEEIRRLLQILSRRTKNNPILVGEPGTGKTAIAEGLAHRIVDGDVPENLKDKLIFSLDM
GALIAGAKYKGEFEERLKAVIKEVTTSEGDIVLFIDEIHTLVGAGGGQGAMDAANILKPALARGELRAIGATTLDEYQKY
FEKDKALERRFQKVQVNEPDTESAISILRGIKEKYETHHKVRIKDEAIIGAVELSQRYITNRFLPDKAIDLMDEAASKLR
MEINSKPEELDVLDRKVMQLEIEIEAIKREKDEVKLNSLRSDLANLKEERNEINAKWKSEKEVVDNIQNTKAAIEDFKSE
AEKAEREGDYGKVAEIRYGKIKKAQEDLEAYQKVLQENQNEKSLIKEEVTLDDIAEVVAKWTGIPVTKMIQSEREKLLKL
EDQLHKRVVGQEEAIVAISDAVRRSKAGLQNPNKPIGSFLFLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDTFNVLLQVLDEGRLTDNKGRVADFKNAIIIMTSNMGS
HIIQEKFSDPKADLDAVTELAKIEVLGLLKKSVRPEFLNRIDDVIMFTPLNKVDIFEIVKLQIDQLKKMIGKQEITLDAT
DEAITYLAQKGFQPEFGARPVKRVIQKEVLNQLSKEILAGRITTDSIILLDAFDDKLVFRNQSDLVEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-103 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-103 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_007670406.1 ATP-dependent Clp protease VFG2076 Protein 5e-128 44
clpB YP_007670406.1 ATP-dependent Clp protease VFG2084 Protein 5e-112 41