Gene Information

Name : H681_18420 (H681_18420)
Accession : YP_007659091.1
Strain : Pseudomonas denitrificans ATCC 13867
Genome accession: NC_020829
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4133186 - 4135555 bp
Length : 2370 bp
Strand : +
Note : COG2217 Cation transport ATPase

DNA sequence :
ATGACTGCCAATCGCCAGGGCCCGATCATCCACGGCCCCGTCCAGGATCAGGAACACAGCGCTACCGCGAGCTGCTGCGG
CTGCGACAGGGGCGCGCTGCTGCGCACGCCGCTGGCCGAACCCGCCACTCGCCATCACGAGCATGATCATGACCACGGCC
ATGCCCACGATCACGATCACGATCACGATCACGATCACGGACAGGGTGAAGATCGCAGCGCGCGGGCCCGCGACGCCGCC
ACTGCGGCGAGCGGCGCGGCCGGCGGAGAACTGCGCTGGACCAGCCTGCGCATCGAAGCGATGGACTGCCCCACCGAGGA
ACGCCTGCTGCGCGATGCCCTCAGCCGGGTGCCAGCGGTGGAAAACCTCGACTTCAACCTGATGCAGCGCCTGCTGCGCG
TGCAGCACCGCTTCGACAGCATCGAACCGCTGCAGAAGCTGGTGGCCTCGCTGGGCATGCAGGCCGAACCGCTCGACGAC
AACGCTCCGATGACTGCGCCAGCCACCCGGCACAAGCCCTGGTGGCCACTGGCGCTGGCCGGCGTGGCGGCGGCCGCTGC
GGAGTTCTTCGAATGGTTCGCCATCGGCCCGCAGTGGCTGGTAGCGGCGTTGGCGGTGGCGGCCATCCTCGGCGCCGGCC
TGCCGACCTACCGCAAGGGCTGGATCGCGCTGAAGAACCGCAACCTGAACATCAACGCGCTGATGAGCATCGCGGTGACC
GGCGCCATGCTGATCGGCCAGTGGCCGGAAGCGGCGATGGTCGCGGTGCTGTTCGCCATCGCCGAGCTGATCGAGGCGAA
ATCCCTGGAGCGCGCGCGCAACGCCATCCGTGGACTGCTGCAACTGGCGCCGGAGCTGGCCACCGTGCAGGTCGACGGCG
AATGGCGCGAGGTGCAGGCCAAGTCGGTGGCGCTGGAGTCCCGCGTCCGTGTGCGCCCCGGCGAACGCATCGCGCTGGAT
GGCGAAGTGCTCGACGGCCGCTCCAGTGTCAACCAGGCGCCCATCACCGGCGAAAGCCTGCCGGTGGAGAAACAGGCGGG
CGACCCGCTGTTCGCCGGCACCATCAACGGCGAAAGCGCGCTGGAATACCGCGTCACCCGCGTCGCCGACGACAGCACCC
TGGCGCGGATCATCCACGCCGTGGAGGAAGCCCAGGGCTCCCGCGCGCCGACCCAGCGCTTCGTCGACCAGTTCTCGCGC
ATCTACACACCGGTGGTGTTCCTCATCGCCATCGCCACCGCCCTGCTGCCACCGCTGTTCTTCGGCGGCGCCTGGCTGGA
CTGGGTGTACCGCGCGCTGGTGCTGCTGGTGATCGCCTGCCCTTGCGCCCTGGTGATCTCCACCCCGGTGACCATCGTCA
GCGGCCTGTCGGCGGCGGCACGCCTGGGCATTCTGATCAAGGGCGGGGTGTTCCTCGAGCTGGGCCGTTCGCTGGCCTGG
ATCGCTCTGGACAAGACCGGCACCCTGACCGAAGGCCGCCCGCGCCAGACCGATTACTCGCCCCTGCGCGAACTGCCCGA
CGCCAATGTGCGAGCCCTGGCCGCCAGCCTGGCCGCGCGCTCCGACCACCCGGTCTCGCAGGCCGTGGCCCGCGCCGCCG
AAACGGACAATATCGCGCTCTACAACGTCGGCGAACTGACCGCCCTGCCAGGCCGTGGCGTGAAGGGAGAGATCGACGGC
CGCCTCTACCATCTGGGCAACCATCGCCTGGTGGAAGAGCTGGAACTGTGCTCGACGGAACTGGAAGCCCGCCTCGACGC
CCTGGAACAGCAAGGCAAGACAGTCATCGTGCTGCTCGACGACAACGGCCCGCTGGCGCTCTTCGCGGTGGCCGACGCGG
TGAAGGAAACCAGCCGCGAAGCGGTGGCACAGTTGCACGAACTGGGCGTGAAAACCCTGATGCTCACCGGCGACAACCCG
CACACCGCCGCCGCCATTGGCGCCCAGGTGGGCATCGATGCGGCGCAGGGCAACCTGCTGCCGGAAGACAAGCTCAATGA
GGTGAAGCAGCGCCAGGAAGGCGGCTACCGTGTGGGCATGGTCGGCGACGGCATCAACGACGCCCCCGCCCTCGCCCGCG
CCGACATCGGCTTCGCGATGGGCGCGGCGGGTACCGACACTGCCATCGAAACCGCCGGCGTAGCGCTGATGGACGACGAC
CTGCGCAAGCTACCGTCCTTCATCCGCCTGTCGCGCCGGACCCACCGCGTGCTGATCCAGAACATCAGCCTGGCGCTGGG
CATCAAGGCAGTGTTCCTGGCCCTGACCCTGGCCGGCGAGGGTACCTTGTGGATGGCGGTGTTCGCCGACATGGGCGCCA
GCCTGCTGGTGGTGTTCAACGGGTTGCGGCTGTTGCGGTACCAGGGTTGA

Protein sequence :
MTANRQGPIIHGPVQDQEHSATASCCGCDRGALLRTPLAEPATRHHEHDHDHGHAHDHDHDHDHDHGQGEDRSARARDAA
TAASGAAGGELRWTSLRIEAMDCPTEERLLRDALSRVPAVENLDFNLMQRLLRVQHRFDSIEPLQKLVASLGMQAEPLDD
NAPMTAPATRHKPWWPLALAGVAAAAAEFFEWFAIGPQWLVAALAVAAILGAGLPTYRKGWIALKNRNLNINALMSIAVT
GAMLIGQWPEAAMVAVLFAIAELIEAKSLERARNAIRGLLQLAPELATVQVDGEWREVQAKSVALESRVRVRPGERIALD
GEVLDGRSSVNQAPITGESLPVEKQAGDPLFAGTINGESALEYRVTRVADDSTLARIIHAVEEAQGSRAPTQRFVDQFSR
IYTPVVFLIAIATALLPPLFFGGAWLDWVYRALVLLVIACPCALVISTPVTIVSGLSAAARLGILIKGGVFLELGRSLAW
IALDKTGTLTEGRPRQTDYSPLRELPDANVRALAASLAARSDHPVSQAVARAAETDNIALYNVGELTALPGRGVKGEIDG
RLYHLGNHRLVEELELCSTELEARLDALEQQGKTVIVLLDDNGPLALFAVADAVKETSREAVAQLHELGVKTLMLTGDNP
HTAAAIGAQVGIDAAQGNLLPEDKLNEVKQRQEGGYRVGMVGDGINDAPALARADIGFAMGAAGTDTAIETAGVALMDDD
LRKLPSFIRLSRRTHRVLIQNISLALGIKAVFLALTLAGEGTLWMAVFADMGASLLVVFNGLRLLRYQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-124 49
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-124 49
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-123 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
H681_18420 YP_007659091.1 cadmium-translocating P-type ATPase BAC0298 Protein 0.0 69
H681_18420 YP_007659091.1 cadmium-translocating P-type ATPase BAC0461 Protein 2e-88 42
H681_18420 YP_007659091.1 cadmium-translocating P-type ATPase BAC0100 Protein 5e-62 41