Gene Information

Name : fliI (G432_06760)
Accession : YP_007615673.1
Strain : Sphingomonas sp. MM-1
Genome accession: NC_020561
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1391433 - 1392776 bp
Length : 1344 bp
Strand : -
Note : COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
GTGCTGACACTCGCGTCCGCCGAGGCGGGGCTGCGCGCGCTTTCGCCCGATCGCCGCTACGGCCGGGTGGTGGCGGTGCG
CGGCGCGCTGATCGAGGTGGAGGGACTGGCCGGCGCCGCCCAGATCGGATCGCGCATCCGCGTCGCTTCCCCCGGCGGCA
CCGTGGAGGCCGAAGTCACCGGCCTCGATCGCGGCATCGCCCACTGCCTGCCGTTCAGCGATCCGCAGGGCATCGCATCG
GGCGCGCGGGCGGATATCGCCGCCGGCCAGTTCGCGCTGCGCCCTTCCACCGCCTGGCTCGGCCGGATGATCGATGGCCT
CGGCCGCCCGGTCGACGGCAAGGGCGTGCTGCTGGCGGGCGCCGTGCCGCGCCCGATCAAGGCGATGCCGCCGCTCGCTT
CCGCCCGCGCCCGCGTGGGCGCCAAGATCGAGACCGGCGTGCGCGCGCTCGATATCTTCGCGCCGCTGTGCCTCGGCCAG
CGGCTGGGCCTGTTCGCGGGTTCGGGCGTCGGCAAGTCGACCCTGCTGTCGATGCTGGCGCGCTGGACGCAATGCGACGT
CGCCGTGATCGGGCTGATCGGCGAGCGCGGCCGCGAAGTGCAGGAATTCGTGGAGGACGATCTCGGCCCCGATGGCCTTG
CCCGCAGCGTGGTGGTGGTCGCCACCTCCGACGAACCGGCGCTGATGCGGCGGCAGGCGGCGTGGACCACGCTGGCGGTG
GCGGAATATTTCCGCGACCAGGGCCTGAACGTGCTGTGCCTGATGGATTCGGTCACGCGCTTCGCCATGGCCCAGCGCGA
GATCGGCCTGGCCAGCGGCGAGCCGCCGGCCACCAAGGGCTATACCCCCACCGTGTTCGCGGAGCTGCCGCGCCTGCTGG
AGCGCGCCGGGCCGGGGCTGGCCGGGCAGGGATCGATCACCGGCCTGTTCACCGTGCTGGTGGACGGCGACGATCATAAC
GAGCCGGTGGCGGACGCCGTGCGCGGCATCCTGGACGGCCACGTCGTCATCACCCGCCGGATCGCCGAACGCGGTCGTTA
TCCGGCGATCGACGTGCTGAAATCGGTGTCGCGGACCTTGCCCCACGCGCACAGCGAGGAAGAAAATCTGGTGCGTCTCG
CCGCGCGCCGCACGCTTTCCACCTATGGAGACATGGAGGAGATGGTGCGGCTGGGCGCCTATCGCACCGGCGCCAGCGCC
GAGGTGGATCAGGCGGTGCTGCTGGCGCCGAGGATCGAGGCGCTGCTGAACCAGTCGAAGAACGAACGCGGCCATGCGGG
CGAGGCCTTCGCCGCATTGGCCGCCATCATGGAGGGACCGGAGCCCGATGAAGACGCCCTATGA

Protein sequence :
MLTLASAEAGLRALSPDRRYGRVVAVRGALIEVEGLAGAAQIGSRIRVASPGGTVEAEVTGLDRGIAHCLPFSDPQGIAS
GARADIAAGQFALRPSTAWLGRMIDGLGRPVDGKGVLLAGAVPRPIKAMPPLASARARVGAKIETGVRALDIFAPLCLGQ
RLGLFAGSGVGKSTLLSMLARWTQCDVAVIGLIGERGREVQEFVEDDLGPDGLARSVVVVATSDEPALMRRQAAWTTLAV
AEYFRDQGLNVLCLMDSVTRFAMAQREIGLASGEPPATKGYTPTVFAELPRLLERAGPGLAGQGSITGLFTVLVDGDDHN
EPVADAVRGILDGHVVITRRIAERGRYPAIDVLKSVSRTLPHAHSEEENLVRLAARRTLSTYGDMEEMVRLGAYRTGASA
EVDQAVLLAPRIEALLNQSKNERGHAGEAFAALAAIMEGPEPDEDAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-74 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-74 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-74 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-74 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-75 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-75 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-73 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-73 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-74 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 7e-67 48
lscN AAO18044.1 LscN Virulence TTSS locus Protein 9e-67 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-57 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-65 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-65 47
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-66 47
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-66 47
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-66 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-57 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 8e-58 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-58 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-56 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-62 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-62 45
escN AAC38383.1 EscN Virulence LEE Protein 9e-66 45
unnamed AAL06369.1 EscN Virulence LEE Protein 6e-66 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-59 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 6e-60 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-64 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-59 44
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-64 44
escN AAC31513.1 L0034 Virulence LEE Protein 4e-65 44
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-65 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-64 44
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-64 44
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-65 44
escN AAK26715.1 EscN Virulence LEE Protein 6e-64 44
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-65 44
escN AAL57542.1 EscN Virulence LEE Protein 6e-64 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-65 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-64 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-56 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-55 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-53 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-53 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-53 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-53 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_007615673.1 flagellum-specific ATP synthase VFG1254 Protein 2e-73 49
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0048 Protein 1e-70 49
fliI YP_007615673.1 flagellum-specific ATP synthase VFG2331 Protein 1e-72 48
fliI YP_007615673.1 flagellum-specific ATP synthase VFG2144 Protein 4e-73 47
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0390 Protein 1e-68 47
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0515 Protein 9e-67 47
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0192 Protein 1e-66 46
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0730 Protein 5e-66 45
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0812 Protein 2e-65 44
fliI YP_007615673.1 flagellum-specific ATP synthase VFG0555 Protein 1e-53 43