Gene Information

Name : guaA (ERDMAN_3716)
Accession : YP_007612166.1
Strain : Mycobacterium tuberculosis Erdman (ATCC35801)
Genome accession: NC_020559
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamineamidotransferase protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3794313 - 3795890 bp
Length : 1578 bp
Strand : -
Note : simliar to Rv3396c of M. tuberculosis H37Rv

DNA sequence :
GTGGTGCAGCCTGCTGACATCGACGTGCCTGAGACACCGGCTCGACCGGTGTTGGTGGTCGACTTCGGTGCCCAATATGC
CCAGTTGATTGCCCGTCGGGTTCGAGAAGCACGGGTTTTCTCCGAGGTGATTCCGCACACCGCCTCGATCGAGGAGATCA
GGGCCCGTCAGCCGGTGGCGCTCGTGCTTTCCGGTGGACCGGCCAGTGTCTACGCCGACGGCGCTCCGAAACTCGATCCG
GCGCTACTGGACCTCGGTGTACCGGTTCTTGGCATCTGCTACGGGTTTCAGGCCATGGCGCAGGCGCTCGGGGGGATCGT
CGCCCACACCGGCACTCGCGAATACGGTCGGACTGAACTGAAAGTCCTTGGTGGCAAACTGCATTCGGATCTTCCCGAGG
TTCAGCCGGTATGGATGAGTCACGGTGACGCGGTCACGGCCGCGCCGGACGGATTCGACGTGGTGGCTAGCAGCGCCGGT
GCCCCGGTGGCCGCCTTCGAGGCCTTCGACCGGCGCCTGGCCGGGGTGCAGTATCACCCGGAGGTGATGCACACCCCACA
CGGGCAACAGGTGCTCAGCCGGTTTTTGCACGACTTCGCCGGGCTCGGCGCCCAGTGGACGCCCGCCAACATCGCCAACG
CGCTGATCGAGCAGGTGCGCACCCAGATCGGCGACGGCCACGCCATCTGCGGGCTATCCGGCGGCGTGGATTCCGCGGTG
GCCGCGGCCCTGGTGCAGCGGGCCATCGGCGACCGGTTGACCTGTGTCTTCGTCGACCACGGGCTGTTGCGCGCCGGTGA
GCGGGCGCAGGTGCAACGCGATTTCGTGGCCGCCACCGGCGCCAACCTGGTCACCGTCGACGCGGCCGAGACCTTCCTCG
AGGCGCTGTCGGGCGTGAGCGCCCCCGAGGGCAAACGCAAGATCATCGGCCGTCAGTTCATCCGCGCGTTCGAGGGCGCG
GTGCGGGATGTGCTGGACGGTAAGACTGCTGAGTTCCTGGTGCAGGGCACGCTGTATCCGGATGTGGTGGAGTCCGGCGG
GGGCAGCGGCACCGCGAACATCAAGAGCCACCACAATGTCGGCGGCCTGCCCGACGACCTGAAGTTCACCCTCGTTGAGC
CGCTGCGGCTGCTGTTCAAAGACGAGGTGCGCGCGGTCGGGCGGGAGTTGGGTCTGCCGGAGGAGATCGTGGCGCGCCAG
CCGTTTCCGGGACCGGGGTTGGGTATTCGGATCGTCGGGGAGGTCACCGCCAAGCGGGTGGATACGCTGCGGCACGCCGA
TTCGATCGTGCGTGAGGAGCTGACCGCGGCGGGCCTGGACAACCAGATCTGGCAGTGTCCGGTGGTGCTGTTGGCCGATG
TCCGCTCGGTGGGTGTGCAGGGTGACGGTCGCACCTATGGCCACCCGATTGTGCTGCGTCCGGTGTCGAGTGAAGACGCG
ATGACCGCCGACTGGACCCGGGTGCCCTACGAGGTGCTCGAGCGCATCTCGACCCGGATCACCAACGAGGTCGCCGAGGT
CAACCGCGTGGTGCTGGACATCACCAGCAAGCCGCCCGCCACCATCGAGTGGGAGTAG

Protein sequence :
MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDP
ALLDLGVPVLGICYGFQAMAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAG
APVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAV
AAALVQRAIGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVSAPEGKRKIIGRQFIRAFEGA
VRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQ
PFPGPGLGIRIVGEVTAKRVDTLRHADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDA
MTADWTRVPYEVLERISTRITNEVAEVNRVVLDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 78
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-130 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-130 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-130 51