Gene Information

Name : lysS (ERDMAN_1805)
Accession : YP_007610277.1
Strain : Mycobacterium tuberculosis Erdman (ATCC35801)
Genome accession: NC_020559
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 1832158 - 1835409 bp
Length : 3252 bp
Strand : -
Note : simliar to Rv1640c of M. tuberculosis H37Rv

DNA sequence :
GTGATCGCGACCCTGTCACTACTGGCCAGTGTGTCGCCGTTGATTCGGTGGATCATCAAGGTTCCGCGCGAATTCATCAA
CGATTATCTGTTCAACTTCCCCGACACCAACTTCGCGTGGTCCTTCGTGCTGGCATTGCTGGCCGCCGCGTTAACGGCAC
GCAAACGCATTGCCTGGTTGGTCTTGCTGGCAAATATGGTCCTGGCCGCCGTGGTCAACGCCGCCGAGATCGCAGCGGGC
GGCAACACCGCCGCCGAGAGCTTCGGGGAGAATCTCGGATTCGCCGTGCATGTTGTGGCAATCGTCGTTCTGGTGCTGGG
CTATCGGGAGTTCTGGGCCAAGGTCCGCAGGGGCGCGCTGTTTCGGGCGGCTGCGGTGTGGCTTGCCGGCGCGGTGGTCG
GAATCGTGGCGTCTTGGGGTCTGGTCGAACTGTTTCCGGGATCACTAGCGCCGGACGAGCGGTTGGGTTACGCGGCCAAC
CGGGTGGTCGGATTCGCCCTCGCCGATCCCGATCTGTTCACCGGCAGACCGCACGTCTTCCTCAACGCGATCTTCGGGTT
GTTCGGCGCGTTCGCGTTGATCGGGGCTGCGATCGTCTTGTTCCTATCTCAGCGCGCTGACAATGCGCTGACCGGAGAGG
ACGAATCCGCTATCCGCGGGTTATTGGATTTGTATGGGAAGGACGACTCACTGGGCTACTTCGCCACCCGTCGCGACAAG
TCGGTGGTATTCGCATCCAGCGGCCGCGCCTGTATCACCTACCGTGTCGAGGTCGGTGTCTGCCTAGCCAGCGGCGACCC
GGTAGGCGACCACAGAGCATGGCCGCAGGCCGTCGACGCGTGGCTGCGGCTGTGCCAGACCTACGGCTGGGCACCCGGCG
TGATGGGCGCCAGTTCACAAGGGGCTCAGACATATCGCGAAGCGGGCCTAACCGCGCTCGAGCTGGGCGATGAGGCCATC
CTGCGGCCAGCCGATTTCAAGTTGTCCGGCCCGGAGATGCGCGGGGTGCGCCAGGCCGTGACGCGGGCCCGGCGGGCGGG
GTTGACGGTGCGCATCCGGCGGCATCGCGACATTGCCGAAGACGAGATGGCGCAGACCATCACACGGGCGGATTCCTGGC
GCGACACCGAGACCGAGCGCGGCTTCTCGATGGCGCTGGGCCGCCTCGGCGACCCCGCGGACTCCGACTGCCTGCTGGTG
GAGGCGATTGATCCGCACAACCAGGTGCTGGCAATGCTGTCGCTGGTGCCGTGGGGAACCACCGGTGTCTCCCTGGATTT
GATGCGTCGTTCTCCACAATCCCCGAACGGCACTATCGAACTTATGGTCAGCGAACTCGCCTTGCACGCTGAAAGCCTTG
GTATCACTCGTATTTCGTTGAACTTCGCGGTGTTTCGCGCGGCCTTCGAGCAGGGCGCCCAACTCGGCGCCGGCCCGGTT
GCCCGGTTGTGGCGGGGGCTGCTGGTCTTCTTCTCACGGTGGTGGCAGCTCGAGACGCTCTACCGCTCCAACATGAAGTA
CCAACCCGAATGGGTACCGCGCTACGCCTGCTACGAAGACGCCCGAGTGATTCCCCGAGTGGGCGTCGCCTCGGTGATCG
CAGAGGGGTTCCTCGTGCTGCCGTTCAGCCGGCGCAACCGAGTACACACGGGGCATCATCCGGCAGTGCCCGAGCGGTTG
GCGGCCACCGGCCTATTGCATCACGACGGCTCGGCACCGGACGTGAGCGGGCTGCGGCAAGTAGGCCTCACCAATGGCGA
CGGGGTCGAGCGGCGGCTACCCGAGCAGGTGCGAGTTCGGTTCGACAAGCTAGAGAAGCTGCGGAGCAGCGGCATTGACG
CCTTTCCCGTGGGCCGGCCGCCCAGTCACACGGTGGCACAGGCGCTGGCCGCAGACCACCAGGCTAGCGTGTCGGTGTCC
GGACGCATCATGCGAATACGTAACTACGGTGGTGTGTTGTTCGCCCAGCTGCGCGACTGGTCGGGCGAAATGCAAGTGCT
GCTGGATAATTCACGCCTGGACCAGGGCTGCGCGGCCGACTTCAACGCGGCGACCGATCTGGGTGATCTGGTGGAGATGA
CCGGACACATGGGCGCCAGCAAGACCGGAACTCCATCGTTGATCGTCAGCGGCTGGCGCCTGATCGGTAAGTGTTTGCGA
CCGTTGCCGAATAAGTGGAAGGGGCTACTGGATCCCGAAGCCCGAGTCCGGACCCGTTACCTCGACCTGGCGGTCAACGC
TGAGTCCCGTGCGCTGATCACCGCTCGCAGCAGCGTGCTGCGCGCTGTGCGCGAGACGCTGTTCGCAAAGGGATTCGTCG
AGGTCGAAACGCCGATCCTACAGCAGCTGCACGGCGGCGCCACCGCCCGACCGTTCGTCACGCACATCAACACGTATTCC
ATGGATCTGTTCCTGCGCATCGCACCAGAGCTCTACCTCAAGCGCCTGTGCGTCGGCGGCGTGGAACGGGTATTCGAGCT
CGGCCGTGCCTTTCGCAACGAGGGCGTCGACTTCAGCCACAACCCGGAGTTCACCCTACTGGAGGCCTATCAAGCACACG
CCGACTACCTTGAGTGGATTGACGGCTGCCGCGAACTCATCCAGAACGCCGCCCAGGCCGCCAACGGGGCGCCCATCGCC
ATGCGGCCCCGGACGGACAAGGGTTCCGACGGCACCCGCCACCACCTCGAACCGGTCGACATCTCCGGGATATGGCCGGT
GCGGACGGTGCATGATGCGATCTCGGAAGCACTCGGTGAACGCATCGACGCCGATACCGGCTTGACCACTCTCCGCAAGC
TGTGCGACGCCGCCGGTGTCCCCTATCGGACCCAATGGGATGCCGGCGCGGTCGTGCTCGAGCTATACGAGCACCTGGTG
GAGTGCCGCACCGAGCAACCGACGTTCTACATCGACTTTCCGACATCGGTGTCACCGTTGACCCGACCGCATCGCAGCAA
GCGCGGTGTCGCCGAGCGTTGGGACCTGGTGGCGTGGGGTATCGAGCTGGGCACCGCCTACAGCGAGCTGACCGACCCGG
TGGAGCAACGGCGCCGCCTGCAGGAGCAGTCCCTGCTGGCCGCCGGCGGAGACCCCGAGGCGATGGAACTCGACGAAGAC
TTCCTGCAAGCGATGGAGTACGCCATGCCGCCCACCGGCGGCTTGGGCATGGGCATTGACCGGGTGGTCATGCTGATCAC
TGGGCGCAGCATTCGCGAAACACTGCCCTTTCCGTTGGCAAAACCGCATTAG

Protein sequence :
MIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAVVNAAEIAAG
GNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAPDERLGYAAN
RVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDK
SVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLTALELGDEAI
LRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLV
EAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPV
ARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTGHHPAVPERL
AATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAADHQASVSVS
GRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSGWRLIGKCLR
PLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYS
MDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAAQAANGAPIA
MRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAVVLELYEHLV
ECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDED
FLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-155 43
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-155 43
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-155 43
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-155 43