Gene Information

Name : tkt (ERDMAN_1612)
Accession : YP_007610085.1
Strain : Mycobacterium tuberculosis Erdman (ATCC35801)
Genome accession: NC_020559
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : -
COG ID : -
EC number : 2.2.1.1
Position : 1621108 - 1623210 bp
Length : 2103 bp
Strand : -
Note : simliar to Rv1449c of M. tuberculosis H37Rv

DNA sequence :
GTGACCACACTCGAAGAGATCTCCGCGCTTACCCGACCGCGCCATCCCGACGACTGGACCGAGATCGATTCGGCTGCCGT
CGACACCATCCGGGTATTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTGGCTC
CGTTGGCCTACACGCTGTTTCAGCGGACAATGCGTCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTT
TTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATTGA
GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCC
CGCTGGGGCAGGGACTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAGCGCGGCCTGTTCGACCCGGACGCC
GAACCGGGCGCCAGCCCCTTCGACCACTACATCTATGTCATCGCCTCCGACGGTGACATCGAAGAAGGGGTGACCTCGGA
GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACG
ACACCAACATCGCGCTGTGTGAGGACACCGCGGCCCGCTACCGCGCGTACGGCTGGCACGTGCAAGAGGTTGAGGGCGGT
GAGAACGTCGTCGGCATCGAGGAGGCCATCGCCAATGCGCAGGCGGTCACCGACCGGCCCTCGTTCATCGCGCTGCGCAC
CGTCATCGGCTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGACGACGAGGTGGCCG
CAGTCAAGAAGATCGTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTG
GTGGCCCGCGGCAAACAGGCCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCGCGGCGTGAACCCGAGCGCAAGGC
GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCCCACTGGGAACCGGGGTCCAAGG
CGCTGGCCACCCGTGCGGCCTCGGGTGCGGTGCTGTCCGCGCTCGGGCCGAAACTGCCCGAGTTGTGGGGCGGTTCGGCC
GACCTGGCGGGCAGCAACAACACAACGATAAAGGGCGCCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAGTACAC
CGCGCACTGGTATGGTCGCACCTTGCACTTCGGTGTTCGCGAGCACGCGATGGGTGCCATCCTGTCCGGCATCGTGCTGC
ACGGACCCACCCGGGCTTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCGGCGGTGCGGCTGGCGGCGTTG
ATGGACATCGACACCATCTACGTCTGGACGCACGACTCGATCGGCCTCGGCGAAGACGGGCCCACCCATCAACCGATCGA
GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACAGCCTACGCCTGGC
GCACGATCCTGGCCCGCCGCAACGGCAGCGGGCCGGTCGGGTTGATCCTGACCCGCCAGGGTGTGCCGGTGCTGGACGGC
ACCGACGCCGAGGGGGTTGCCCGCGGCGGTTACGTGCTGAGTGACGCCGGTGGTCTGCAACCGGGCGAGGAACCCGACGT
CATTCTCATCGCCACCGGCTCGGAGGTGCAGCTGGCGGTCGCGGCGCAGACGTTGCTGGCGGACAACGACATCCTCGCTC
GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG
TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCAGCTGGTTGGCGACACGGGCGAGATCGTCTCGAT
CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCG
CCGAACGAGCGCTGGATAACTGA

Protein sequence :
MTTLEEISALTRPRHPDDWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV
LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
EPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGG
ENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGL
VARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSA
DLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAAL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDG
TDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV
SARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-113 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-112 42