Gene Information

Name : BN418_0259 (BN418_0259)
Accession : YP_007602450.1
Strain : Listeria monocytogenes La111
Genome accession: NC_020557
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 237390 - 239852 bp
Length : 2463 bp
Strand : +
Note : -

DNA sequence :
ATGATGTTTGGACGATTTACGCAAAGAGCTCAGAAAGTACTCGCGTTGTCACAAGAAGAGGCGATGCGTTTGAATCATAG
TAATTTAGGAACAGAACATATTTTATTAGGGCTTGTAAGAGAAGGCGAAGGAATTGCGGCGAAAGCTCTCTATGAACTGG
GAATTAGTTCTGAAAAAGTGCAGCAAGAGGTAGAGGGATTAATTGGGCATGGGGAAAAAGCTGTGACGACGATCCAATAT
ACACCTCGTGCGAAAAAAGTAATTGAACTTTCCATGGATGAGGCTCGTAAATTAGGCCATACTTACGTTGGGACAGAACA
TATCTTACTTGGGCTTATTCGTGAAGGCGAAGGAGTTGCGGCACGCGTTTTAAGTAATCTTGGTATTAGTTTAAATAAAG
CTCGGCAGCAAGTTCTACAGCTCTTAGGCGGCGGTGATGCTACTGGGGCGGGGAGACAAACAAATACGCAAGCTACACCG
ACTTTAGATAGTTTGGCACGTGACTTAACGGTTATTGCTCGGGAAGATAATTTGGATCCGGTTATTGGTCGTTCTAAAGA
AATCCAACGTGTGATTGAAGTACTTAGTCGCCGGACGAAAAATAACCCGGTACTCATTGGGGAACCTGGTGTCGGTAAAA
CAGCGATTGCTGAAGGCTTAGCGCAACAAATTGTTCGTAATGAAGTACCTGAGACCTTACGTGGAAAACGTGTAATGACA
TTGGATATGGGAACTGTTGTGGCAGGTACAAAATATCGTGGTGAATTCGAAGACCGTTTGAAGAAAGTAATGGATGAAAT
TCGTCAAGCTGGTAATGTTATTCTATTTATTGATGAATTGCATACTTTAATTGGTGCTGGTGGGGCGGAAGGTGCGATTG
ATGCATCGAATATCTTGAAGCCACCGCTAGCTCGTGGAGAGTTGCAATGTATTGGGGCAACAACGCTCGACGAGTACCGT
AAATATATTGAAAAAGATGCTGCGCTTGAGAGACGTTTCCAACCGATTAAAGTAGACGAACCAACTGTAGAAGAATCTAT
TCAAATTTTACATGGATTGCGTGATCGTTATGAAGCGCATCACCGAGTTGCAATTACGGATGAAGCACTTGAGGCCGCTG
TTCGTTTATCTGATCGCTATATTTCAGACCGTTTCTTACCTGATAAAGCGATTGATGTTATCGATGAATCTGGTTCTAAA
GTACGTTTGAAATCTTTTACAACGCCAAAAAATGTAAAAGAAATGGAAAATAATTTATCCGATTTGAAAAAAGAAAAAGA
TGCGGCTGTTCAAGGTCAAGAATTTGAAAAAGCAGCGTCATTACGTGATAAAGAACAAAAACTCAAAAAATCATTAGAAG
AAACTAAAGCGAATTGGCAAGAAAAACAAGGGCTTGACCATAGTGAAGTAACAGAAGATATTGTCGCTGAAGTGGTTGCT
AGTTGGACTGGGATTCCAGTTGCGAAACTTGCGGAAACAGAGACAAATAAACTGTTAAATATGGAAAAACTTTTACATGA
ACGTGTGATTGGACAAGATGCAGCGGTTAAAGCTGTATCGCTAGCTGTACGTCGAGCTCGTGCAGGCCTTAAAGATCCGA
AACGTCCGATTGGTTCCTTTATTTTCCTTGGACCTACTGGTGTTGGGAAAACAGAACTTGCGCGTGCACTTGCTGAGTCG
ATGTTTGGCGATGAGGATTCGATGATTCGGATTGATATGTCTGAGTACATGGAGAAATTTTCAACTGCTCGTTTAGTTGG
GGCTCCTCCAGGTTATGTAGGATACGAAGAAGGTGGACAGCTGACAGAAAAAGTTCGGCAAAAACCTTATTCAGTAGTCC
TTTTAGATGAAATTGAAAAAGCACATCCGGATGTATTTAATATGTTGCTACAAGTACTGGATGATGGACGTTTGACTGAT
TCTAAAGGGCGAGTAGTTGATTTTAGAAATACAGTTATCATTATGACTTCCAATATTGGAGCTCAAGAAATGAAACAAGA
TAAATCAATGGGCTTTAATGTTACTGATCCACTTAAAGACCATAAAGCGATGGAGCACCGCGTTTTACAAGATTTAAAAC
AGGCGTTCCGACCAGAATTTATCAACCGAATTGATGAAACAATTGTATTCCATTCGCTGCAAGAAAAAGAATTGAAACAA
ATTGTTACTTTACTAACTGCTCAATTAACAAAACGCTTAGCCGAACGCGATATTCACGTGAAATTAACTGAAGGTGCGAA
ATCCAAAATCGCTAAAGATGGCTACGATCCAGAGTACGGAGCTCGTCCTTTAAAACGGGCTATTCAAAAAGAAGTGGAAG
ACATGCTTTCTGAAGAATTGCTTCGTGGTAACATTAAAGTAGGCGATTACGTTGAAATTGGTGTGAAAGATGGCAAGTTA
GAGGTTAGAAAAAAAGATGCTCCTAAAAAGAAAACAACCTCTAAAAAAGTAAAAGCTAAATAA

Protein sequence :
MMFGRFTQRAQKVLALSQEEAMRLNHSNLGTEHILLGLVREGEGIAAKALYELGISSEKVQQEVEGLIGHGEKAVTTIQY
TPRAKKVIELSMDEARKLGHTYVGTEHILLGLIREGEGVAARVLSNLGISLNKARQQVLQLLGGGDATGAGRQTNTQATP
TLDSLARDLTVIAREDNLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVRNEVPETLRGKRVMT
LDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNILKPPLARGELQCIGATTLDEYR
KYIEKDAALERRFQPIKVDEPTVEESIQILHGLRDRYEAHHRVAITDEALEAAVRLSDRYISDRFLPDKAIDVIDESGSK
VRLKSFTTPKNVKEMENNLSDLKKEKDAAVQGQEFEKAASLRDKEQKLKKSLEETKANWQEKQGLDHSEVTEDIVAEVVA
SWTGIPVAKLAETETNKLLNMEKLLHERVIGQDAAVKAVSLAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAES
MFGDEDSMIRIDMSEYMEKFSTARLVGAPPGYVGYEEGGQLTEKVRQKPYSVVLLDEIEKAHPDVFNMLLQVLDDGRLTD
SKGRVVDFRNTVIIMTSNIGAQEMKQDKSMGFNVTDPLKDHKAMEHRVLQDLKQAFRPEFINRIDETIVFHSLQEKELKQ
IVTLLTAQLTKRLAERDIHVKLTEGAKSKIAKDGYDPEYGARPLKRAIQKEVEDMLSEELLRGNIKVGDYVEIGVKDGKL
EVRKKDAPKKKTTSKKVKAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-97 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BN418_0259 YP_007602450.1 Negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 100
BN418_0259 YP_007602450.1 Negative regulator of genetic competence ClpC/MecB VFG0080 Protein 1e-155 53