Gene Information

Name : fliI (HCBAA847_0439)
Accession : YP_007600317.1
Strain : Helicobacter cinaedi ATCC BAA-847
Genome accession: NC_020555
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.-
Position : 430294 - 431712 bp
Length : 1419 bp
Strand : +
Note : similiar to HCN_0415 of H. cinaedi PAGU611

DNA sequence :
ATGCCATTATCTCACATCAAAGAAAAATTAAAACATAATATGAATCTTTCTCCAAGCTACGGGCAGCTTATAAAAGTTAT
GCAAAATATGTTTGTAGCTAATGGTGTGAAGCCTTCAGTTGGCGATATTGTAAAAATTATCCCAAGTAGGCAGAATCTAA
ACGCACAAAATCGTAATGGGAGACTTAATGGGGAGCTTTGTGGCAAATTTGATAAAGAATTTGATAAAGAAGATGAAAGC
GAGATTCACACACAGGGTGAAAAAAAGCAAAGTTTGGGTATGGTGATAGCCATTGAGGGGGAGAAATTTTTTATTAGCCC
ATTTTCCTTTGTAGAGGGGCATAAATGTGGTGATAAGGTGGAGATTCTAAACCACGGGTTAAATATTCCTGTGGGGGAGG
CTATGCTGGGGCGAGTGGTGAATCCTTTGGGAGAGCCTATTGATGATAAGGGGAGTTTGCATACTCAAGCGACAACGCCG
CTTATGCGTTCGCCGCTAAGTGCGTTAAAGCGAGGGCTTATAGATGAAGTCTTTGAGGTGGGGGTAAAATCCATTGATAG
TATTCTTACTTGTGGCAAAGGGCAAAAAATGGGAATCTTTGCTGGAAGTGGCGTAGGCAAATCCACGCTTATGGGTATGA
TAGTGCGTGGGGCAAAAGCACCCATTAAGGTTATTGCATTGATAGGGGAGCGGGGCAGGGAAGTGCCGGAGTTTATCTAT
AAGAATCTTAATAATGATTTGACAAATACCATTCTTGTGGTGGCTACAAGCGATGATTCGCCACTTATGCGTAAATATGG
GGCATTTAGTGCAATGGCTATTGCTGAATATTTTAAATCGCTTGGCAATGATGTGCTGTTTATTATGGATTCTGTTACGC
GTTTTGCTATGGCTCAGCGAGAGATAGGACTAGCCCTAGGAGAGCCACCTACGAGTAAGGGCTATCCCCCATCAGTCTTA
ACGCTCCTGCCACAGCTTATGGAAAGGGCGGGGAAAGAAGATAGCGTAGGCTCTATCACAGCGTTTTTTACCGTGCTAGT
TGAGGGTGATGACTTGAGCGATCCTATTGCAGACCAAAGCAGAAGTATCCTAGATGGGCATATTGTGCTTAATCGTGATT
TGACAGATATGGGAATCTACCCACCGATAAATATTCTAAACTCTGCTTCAAGGATTATTAATGATATTATTAGCCCGGAG
CATTTAGGCTATGTGCGGAAGTTTCGGCGGTTGTATTCATTGATTAAAGAAAATGAAGTGCTTATCCGCATTGGAGCGTA
TCAAAGGGGGGCAGATATAGAACTTGATGAGGCGATAAATAAACGCACAGCAATGGAAGCATTTTTAAAACAAGAGATTG
ATGAAAAGTGGGACTTTCAACGCTCTCTTGATGAGCTATGCAAGATTATGCAGGAGTAG

Protein sequence :
MPLSHIKEKLKHNMNLSPSYGQLIKVMQNMFVANGVKPSVGDIVKIIPSRQNLNAQNRNGRLNGELCGKFDKEFDKEDES
EIHTQGEKKQSLGMVIAIEGEKFFISPFSFVEGHKCGDKVEILNHGLNIPVGEAMLGRVVNPLGEPIDDKGSLHTQATTP
LMRSPLSALKRGLIDEVFEVGVKSIDSILTCGKGQKMGIFAGSGVGKSTLMGMIVRGAKAPIKVIALIGERGREVPEFIY
KNLNNDLTNTILVVATSDDSPLMRKYGAFSAMAIAEYFKSLGNDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSVL
TLLPQLMERAGKEDSVGSITAFFTVLVEGDDLSDPIADQSRSILDGHIVLNRDLTDMGIYPPINILNSASRIINDIISPE
HLGYVRKFRRLYSLIKENEVLIRIGAYQRGADIELDEAINKRTAMEAFLKQEIDEKWDFQRSLDELCKIMQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 6e-78 48
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-81 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-77 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-79 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-79 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-79 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-79 46
escN AAL57542.1 EscN Virulence LEE Protein 9e-79 46
escN AAC38383.1 EscN Virulence LEE Protein 4e-79 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 5e-79 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-79 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-79 46
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-79 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-79 46
escN AAC31513.1 L0034 Virulence LEE Protein 1e-79 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-79 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-79 46
escN AAK26715.1 EscN Virulence LEE Protein 9e-79 46
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-78 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-78 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-76 46
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-76 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-78 46
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-78 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-74 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-74 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-72 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-71 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-71 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-72 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-72 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-57 42
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-57 42
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-55 41
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-54 41
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-54 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-57 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-57 41
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-59 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-54 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 4e-61 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_007600317.1 flagellum-specific ATP synthase VFG0390 Protein 8e-78 51
fliI YP_007600317.1 flagellum-specific ATP synthase VFG0048 Protein 5e-80 51
fliI YP_007600317.1 flagellum-specific ATP synthase VFG2499 Protein 1e-78 49
fliI YP_007600317.1 flagellum-specific ATP synthase VFG2144 Protein 2e-78 47
fliI YP_007600317.1 flagellum-specific ATP synthase VFG1254 Protein 2e-78 47
fliI YP_007600317.1 flagellum-specific ATP synthase VFG0812 Protein 6e-80 46
fliI YP_007600317.1 flagellum-specific ATP synthase VFG0730 Protein 2e-79 46
fliI YP_007600317.1 flagellum-specific ATP synthase VFG2331 Protein 3e-74 45
fliI YP_007600317.1 flagellum-specific ATP synthase VFG0192 Protein 5e-78 45
fliI YP_007600317.1 flagellum-specific ATP synthase VFG0515 Protein 2e-72 45
fliI YP_007600317.1 flagellum-specific ATP synthase VFG1008 Protein 8e-62 45
fliI YP_007600317.1 flagellum-specific ATP synthase VFG1778 Protein 2e-59 44
fliI YP_007600317.1 flagellum-specific ATP synthase VFG2459 Protein 6e-64 42