Gene Information

Name : aadA (ABD1_01350)
Accession : YP_007594687.1
Strain : Acinetobacter baumannii D1279779
Genome accession: NC_020547
Putative virulence/resistance : Resistance
Product : streptomycin 3''-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.47
Position : 163989 - 164777 bp
Length : 789 bp
Strand : +
Note : -

DNA sequence : 
ATGTCTGATTTCATTCAGTTAGAATATCTACAAGAAAAATTACAGCAACTTTTAGCGAAATCATTATTTGCAATCTATCT
TTATGGTTCAGCTGTTGATGGTGGTTTAGGACCAGAAAGTGACCTTGATGTTCTGGTCGTGGTTACTCAACCATTAACAT
CTGCTTTACGCGAGCAGCTTGCACAAGAATTACTAAAAATTTCACAGCCTGTTGGGGAATTACAAAGACCATTAGAAGTT
ACTATTTTATTAAAAGATGAGATTCAGTCTGGAAATTATCCTTTAAGTTATGAAATGCAGTTTGGTGAATGGCTACGTGA
AGAACTTAAAGAAGGTGGAACATTAAGTTCCCAGAAAGACCCAGATATTAGTATATTGCTTAGAAAAGCGAGATTTCATC
ATACAGTTTTATTTGGTCCAGCTTTGGACCAATGGGCACCTGAAATTTCTGATCAAGAACTATGGCAAGCAATGTCTGAT
ACTTATCCCGAAATTGTAGCTCATTGGGATGAGGATGCAGATGAAAGAAACCAGATTTTAGCTTTATGCCGGATCTATTT
TAGTTTAGTCATGAAGGATATTGCTTCAAAAGACAATGCAGCTCGATGGGTTATGCCTCAGCTTCCTCCTGAGCAGAAAT
TCGTATTGCAGCGGCTTATACAGGAATATAGAGGGGAAATAGGCAAACAAAATTGGCAAGAGGAACATTATGCTTTGCAG
CCTATTGTTAATTTTCTGAGTTCAAAAATTGAAGAGCAGTTTGAGCAGAAAAGAAATTTGATCGCATAA

Protein sequence : 
MSDFIQLEYLQEKLQQLLAKSLFAIYLYGSAVDGGLGPESDLDVLVVVTQPLTSALREQLAQELLKISQPVGELQRPLEV
TILLKDEIQSGNYPLSYEMQFGEWLREELKEGGTLSSQKDPDISILLRKARFHHTVLFGPALDQWAPEISDQELWQAMSD
TYPEIVAHWDEDADERNQILALCRIYFSLVMKDIASKDNAARWVMPQLPPEQKFVLQRLIQEYRGEIGKQNWQEEHYALQ
PIVNFLSSKIEEQFEQKRNLIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadA1 ACV89835.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR7 Protein 2e-28 42
aadA1 YP_005797133.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 2e-28 42
unnamed AFV53113.1 AadA1 aminoglycoside (3') adenyltransferase Not tested AbGRI2-1 Protein 2e-28 42
aadA1 YP_005797149.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 2e-28 42
aadA1 AGK36646.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR26 Protein 2e-28 42
aadA1 YP_006098376.1 aminoglycoside adenylyltransferase Not tested Tn2411 Protein 2e-28 42
aadA1 ACN81025.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR5 Protein 2e-28 42
aadA1 ACY75515.1 aminoglycoside adenyltransferase Not tested Tn6060 Protein 3e-28 42
aadA1 CAD92142.1 aminoglycoside adenyltransferase Not tested Not named Protein 3e-28 42
aadDA1 CAJ77087.1 Aminoglycoside 3-adenylyltransferase Not tested AbaR1 Protein 2e-28 42
aadA1 CAJ77048.1 Aminoglycoside adenylyltransferase Not tested AbaR1 Protein 2e-28 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase NC_010400.5986843.p0 Protein 5e-111 99
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase NC_010410.6002671.p0 Protein 2e-110 99
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase AJ704863.gene12.p01 Protein 2e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase AM932669.1.gene3.p01 Protein 1e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase AF313471.1.gene3.p01 Protein 1e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase AY339625.2.gene17.p0 Protein 1e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase Y18050.2.gene6.p01 Protein 2e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase AY123251.gene3.p01 Protein 1e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase NC_010410.6003168.p0 Protein 1e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase JN596991.2.gene3.p01 Protein 2e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase FR748153.1.gene5.p01 Protein 2e-28 42
aadA YP_007594687.1 streptomycin 3''-adenylyltransferase NC_010410.6003170.p0 Protein 1e-28 42