Gene Information

Name : guaA (D805_0901)
Accession : YP_007593608.1
Strain : Bifidobacterium thermophilum RBL67
Genome accession: NC_020546
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1117846 - 1119408 bp
Length : 1563 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGGCGAAAGGTCCAGTGCTCGTCGTCGATTTCGGCGCGCAGTACGCCCAGCTTATCGCGCGTCGCGTGCGCGAAGCCAA
CGTGTATTCCGAGCTTGTGCCCCATTCCATGTCCGCCGACGAGATGCTTGCCAAGGATCCGAAGGCCATCATCCTGTCCG
GCGGCCCGGCCTCCGTGTTCGAGCCCGGGGCCCCTGGCATCGACAAGAAGATCTTCGAGGCCGGCGTCCCGGTGCTTGGC
ATCTGCTATGGCTTCCAGGTTATGGCGTATGAGCTTGGCGGCACTGTTGACAAGGCTGCGCTCGGTGAGTATGGCAAGAC
CGAGACCAGCATTGACGATGCCGAAGGAATTCTCGCCGGTTCCCCTGCCGAGCAGACCACGTGGATGAGCCACGGTGTGG
CTGTGGAGAAGGCGCCTGAGGGCTTCAGGGTGCTCGCCCACACCGAGGGCGCTCCTGTTGCCGCGATGGAGGACGAATCC
CGCAAACTCTACGGCGTGCAGTGGCATCCGGAAGTCAAGCACACCCCGCGCGGCCAGGAGCTTATCGAGACCTTCCTGCA
TAAATGCGCTGGCCTCGACCGCGATTGGGACGCGTCGAACATCATTGAAGACCAGGTCAAGAAGATCCGTGAGGAAGTCG
GGGACGCCCAGGTGATCTGCGGCCTATCCGGCGGCGTGGATTCCGCTGTTGCCGCCGCTCTCGTGCACAAGGCGATCGGC
GACCAGCTGACCTGCGTGTTCGTGGACCATGGCCTGTTGCGCAAGGGCGAGGCCGAGCAGGTCAAGCATGATTTCGTCAA
GGCGACCGGCATCAAGCTCATCGCCGTCGACGCTTCCGAGGACTTCCTCACCGCGCTCAAGGGTGTGTCGGAGCCGGAAC
GCAAGCGCAAGATCATCGGCGAGAAGTTCATCCGTACTTTCGAGAAGGCCCAGCGTCAGGTCATTGAAGAAGCCGGCAAG
AACGGCGCCGAAGTGAAGTACCTCGTGCAGGGCACCCTGTATCCGGATGTCGTCGAGTCCGGCGGCGGTGACGGCGCGGC
CAATATCAAGAGCCACCACAATGTCGGCGGTCTGCCCAAGGACATCAAGTTCAAGCTGATCGAACCGCTGCGCACCCTGT
TCAAGGACGAGGTGCGTGCCATCGGCACCAAGCTCGGTCTGCCGGACGATATCGTTTGGCGTCAGCCGTTCCCCGGCCCG
GGCCTGGGCATCCGAATCATCGGTGAAATTACCCGCGAGCGACTTGATTTGCTGCGTGAGGCCGATGCGATTGCGCGCGA
GGAGCTGTCGAAGGCTGGTCTTGACCGCGATATCTGGCAGTGCCCGGTCGTTCTCCTTGCCGACGTGCATTCCGTGGGCG
TACAGGGTGACGAACGCACGTACGGCTCGCCGATCGTGCTGCGCCCGGTCAGTTCGGAGGACGCGATGACCGCCGATTGG
TCGCGCGTCCCATACGACGTACTCGCGACCATCTCCACGCGCATCACCAACGAATGCCGTGGCATCAACCGCGTGGTGCT
TGACGTGACCAGCAAGCCGCCGGCAACCATCGAATGGGAGTAG

Protein sequence :
MAKGPVLVVDFGAQYAQLIARRVREANVYSELVPHSMSADEMLAKDPKAIILSGGPASVFEPGAPGIDKKIFEAGVPVLG
ICYGFQVMAYELGGTVDKAALGEYGKTETSIDDAEGILAGSPAEQTTWMSHGVAVEKAPEGFRVLAHTEGAPVAAMEDES
RKLYGVQWHPEVKHTPRGQELIETFLHKCAGLDRDWDASNIIEDQVKKIREEVGDAQVICGLSGGVDSAVAAALVHKAIG
DQLTCVFVDHGLLRKGEAEQVKHDFVKATGIKLIAVDASEDFLTALKGVSEPERKRKIIGEKFIRTFEKAQRQVIEEAGK
NGAEVKYLVQGTLYPDVVESGGGDGAANIKSHHNVGGLPKDIKFKLIEPLRTLFKDEVRAIGTKLGLPDDIVWRQPFPGP
GLGIRIIGEITRERLDLLREADAIAREELSKAGLDRDIWQCPVVLLADVHSVGVQGDERTYGSPIVLRPVSSEDAMTADW
SRVPYDVLATISTRITNECRGINRVVLDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-161 67
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-129 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-129 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 54