Gene Information

Name : R2APBS1_3788 (R2APBS1_3788)
Accession : YP_007592081.1
Strain : Rhodanobacter sp. 2APBS1
Genome accession: NC_020541
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4040044 - 4041723 bp
Length : 1680 bp
Strand : +
Note : PFAM: Pyridine nucleotide-disulphide oxidoreductase; Heavy-metal-associated domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase

DNA sequence :
ATGACTGAAACATACGATTTGAACAAACAGGCGCTCGAGGTCAGTGGCATGACCTGCCAGGCGTGCGCTCGCCACGTGCA
GGAGGCGTTGTCCAGCGTGGATGGCGTGACCAGCGCCAGCGTGGACTATCCGACGGCTACCGCCCAGGTGGTGGCCGGTG
CGGCGCTGTCCGTCGCCGCGCTCAATGCCGCACTGCCGCCGCCCTATCGCGTACGAGCGCTGGCGCGGCCGCCGGCCGCG
GATCACGCGGCAAGGCATGGCGGGCCCGTGGCCGGCCATGACGCCCGTTTGCGTGTGGCGGTGATCGGCACCGGCGGCGC
AGCAATGGCTGCGGCGCTCCGGGCCGCCGAGCGCGGTGCGCGGGTCACCGTGATCGAGCGCGGTACCGTCGGCGGCACCT
GCGTCAACATCGGTTGCGTGCCTTCCAAGATCATGATCCGCGCCGCCCACGTCGCCCATACCCGCCGGCACAGCCCGTTC
GATGGCGGCATCGACGCCGGGGCGCCGGCGATCCGGCGCGACGCGCTGCTGGCCCAGCAGCAGGCGCGGGTGGAGGAACT
GCGCCATGCCAAGTACGAGCGCATCCTCGATGGCAATCCGGACATCACGCTGTTGCGCGGCGAAGCGCGCTTCGTCGACG
GCCACACGTTGGGCGTGCGCCTGGCCGAAGGCGGCGAGCGCACGGTGGCTTTCGACCGCTGCCTGATCGCGGTGGGCGCC
CGGCCGGCGGTGCCGCCGATCCCCGGCTTGGCCGACACGCCGTACTGGACGTCCACCGACGCGCTGGCCGCCGACCGCAT
TCCGAAGCGTCTGCTGGTACTCGGCTCGGCCGTGGTGGCCTGCGAGCTTGGCCAGGCCTATGCGCGGCTGGGCAGCCGGG
TGACGATGATCGCCCGCAGCGAGTTGTTCTTCCACGAGGACCCGGCCATCGGCGAAGCCATCGGCCAGATCTTTGCCGAC
GAGGGTATCCGCGTGCTGCGTCAGACCCAGACCCGCGCGGTGCGCCATGAAAACGGCGAGTTCATCCTCGACACCAGCGC
CGGCCAGCTGCGCGGCGATGCGCTGCTGGTAGCCACCGGCCGCACGCCCAACGGCGACACGCTGGAGTTGGCCCAAGCCG
GCGTGCGCACGGGCAAGGGCGGTGCCATCGAAGTCGATGCGCAACTGCGCACTTCGGTGGCGCACATCTACGCCGCCGGC
GACTGCACCGACCAGCCGCAGTTCGTCTATGTCGCCGCCGCCGGCGGCACCCGCGCCGCGATCAACATGACCGGCGGCGA
CGCCCAGCTCGATCTGTCGGCCATGCCAGCGGTGGTGTTCACCGAACCGCAGATCGCCACGGTGGGGCTGAGCGAGGCCG
AGGCGCATCTGAAGGGTATCGAGACCGACAGCCGCACGCTCACCCTGGACAACGTGCCGCGCGCGCTCGCCAACTTCGAC
ACGCGCGGCTTCATCAAGCTGGTGGTGGAGGCGGCCAGCGGCCGGCTGATCGGCGTGCAGGCGGTGGCCGACGGGGCCGG
CGAGCTGATCCAGACCGCGGCCATCGCGCTACGCGCCGGGATGACCGCTGCCGAACTGGCCGACCAGCTGTTTCCGTACC
TGACCATGGTCGAGGGGTTGAAGCTGGCCGCGCAGACCTTCAGCAAGGACGTCAAGCAACTTTCCTGCTGTGCGGGTTGA

Protein sequence :
MTETYDLNKQALEVSGMTCQACARHVQEALSSVDGVTSASVDYPTATAQVVAGAALSVAALNAALPPPYRVRALARPPAA
DHAARHGGPVAGHDARLRVAVIGTGGAAMAAALRAAERGARVTVIERGTVGGTCVNIGCVPSKIMIRAAHVAHTRRHSPF
DGGIDAGAPAIRRDALLAQQQARVEELRHAKYERILDGNPDITLLRGEARFVDGHTLGVRLAEGGERTVAFDRCLIAVGA
RPAVPPIPGLADTPYWTSTDALAADRIPKRLLVLGSAVVACELGQAYARLGSRVTMIARSELFFHEDPAIGEAIGQIFAD
EGIRVLRQTQTRAVRHENGEFILDTSAGQLRGDALLVATGRTPNGDTLELAQAGVRTGKGGAIEVDAQLRTSVAHIYAAG
DCTDQPQFVYVAAAGGTRAAINMTGGDAQLDLSAMPAVVFTEPQIATVGLSEAEAHLKGIETDSRTLTLDNVPRALANFD
TRGFIKLVVEAASGRLIGVQAVADGAGELIQTAAIALRAGMTAAELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-155 75
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-155 75
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-155 75
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-153 75
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 5e-154 75
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-153 74
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-153 74
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-153 74
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-150 73
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 2e-149 73
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-83 45
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 4e-83 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R2APBS1_3788 YP_007592081.1 mercuric reductase BAC0652 Protein 6e-155 74
R2APBS1_3788 YP_007592081.1 mercuric reductase BAC0653 Protein 1e-150 72
R2APBS1_3788 YP_007592081.1 mercuric reductase BAC0650 Protein 8e-146 70
R2APBS1_3788 YP_007592081.1 mercuric reductase BAC0651 Protein 2e-83 45
R2APBS1_3788 YP_007592081.1 mercuric reductase BAC0224 Protein 2e-81 44