Gene Information

Name : R2APBS1_1852 (R2APBS1_1852)
Accession : YP_007590211.1
Strain : Rhodanobacter sp. 2APBS1
Genome accession: NC_020541
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2010450 - 2012174 bp
Length : 1725 bp
Strand : -
Note : PFAM: Pyridine nucleotide-disulphide oxidoreductase; Heavy-metal-associated domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase

DNA sequence :
ATGAACGAACAAACCCTCTCTGTGATCGGCATGACGTGCGCCGATTGCGCCCGACATGTTGAAAAAGCGCTCCGGGCGTT
GCCTGACGTCGTCGCCGCTGACGTCGCCTACCCGCAAAATGTGGCGCACGTCCGTAGTACCCAGCCATTGACGGTGGAGC
AACTCAACGCGGGTCTGCCGCAAAACTACCGGATCGCCGCCGCCTCGGCACCGCAAGCCGACACACTCGCGCGCAAGTCC
TCCATGCTCGACCAGGCCTTGGGCTCGCTGGGTGGTTGGTTCAAGCCGCGTGGCGATGTCGACCGCACGCCCACCGCTTC
GGAGCAGCGACTGCACGTTGCTGTCATCGGCACGGGCGGCGGGGCCATGGCGGCAGCGCTGAAGGCCGTTGAACTCGGCG
CCCGGGTGACCGTCATCGAGCGCGGAACCGTCGGTGGTACCTGCGTCAATATCGGCTGCGTGCCGTCGAAGATCATGATC
CGCGCCGCGCACGTGGCCCACCTGCGTCGAAGCAGTCCGTTCGATGACGGCATCTCCAGTACGGGGCCGGTGGTTCGGCG
TGACCGACTGCTCGCCCAACAGCAAGGTCGTGTCGACGAACTGCGTCACGCCAAGTACGAGGGGATTCTCGATACCAACC
CCAACATCCAGCTGCTGCGTGGCGAAGCGCGTTTCAAGGACGCACACACGCTCGTCGTCACGTCGACGACGGGGCGTGGT
GAATCGGAGGTGTCTTTCGATCGCTGCCTGATCGCCACGGGTGCCCACGCGGCGGTGCCGCCCATCCCCGGCTTGAAGGA
CACCCCGTATTGGACGTCCACCGAGGCATTAGCCAGTGACGCGATTCCGCCGCGGCTCGCCGTCATCGGCTCGTCAGTGG
TTGCGGTGGAATTGGCGCAAGCCTTCGCGCGGTTGGGCAGTCACGTCACCATCTTGGCGCGCAGCAGCTTGTTCTTTCGC
GAAGATCCGGCCATCGGCGAGGCGATCACGGCGGCGTTCCGTGCCGAAGGCATCGAGGTGTTGGAGCACACCCAGGCCAG
CCAAGTTGCCCATGCCAACGGTGAATTCGTGCTCACCACCGGGCACGGCGAAGTGCGTGCCGATCGGTTGCTGGTGGCCA
CGGGCCGGACCGCCAACACGCGTGACCTCGCGCTGGAGGCGGCGGGTGTTGCGGTGAATGCTCAAAACGCCATCGTGGTC
GATCGCGGTATGCGAACCAGTGCGCCGCACATCTATGCTGCGGGCGATTGCACCGACCAGCCGCAGTTCGTCTACGTGGC
GGCCGCCGCCGGTACACGTGCCGCCATCAACCTGATGGGGGGCGAGGCGACCTTGGATCTCACCACCATGCCGGCGGTGG
TGTTCACGGAGCCCCAAGTCGCGACCGTAGGCCTTAGCGAGGCGGAAGCGCACCTGCAGGGTATCGAGACGGATAGCCGC
ACACTTTCACTCGATAACGTGCCGCGGGCGCTCGTCAATTTCGACACCCATGGCTTTATCAAGCTGGTGGCCGAAGCGGG
TAGCGGCCGGCTCATCGGGGTGCAGGCGGTGACGCCGGAAGCCGGCGAGATCATCCAGGCGGCCGCACTGGCGATCCGGG
CGCGCATGACCGTGCAGGAGCTTGCCGATCAGTTGTTCCCGTACCTGACGATGGTCGAGGGCCTGAAACTGGCGGCACAG
ACCTTCACCAAGGACGTCAAGCAACTTTCCTGCTGTGCCGGATGA

Protein sequence :
MNEQTLSVIGMTCADCARHVEKALRALPDVVAADVAYPQNVAHVRSTQPLTVEQLNAGLPQNYRIAAASAPQADTLARKS
SMLDQALGSLGGWFKPRGDVDRTPTASEQRLHVAVIGTGGGAMAAALKAVELGARVTVIERGTVGGTCVNIGCVPSKIMI
RAAHVAHLRRSSPFDDGISSTGPVVRRDRLLAQQQGRVDELRHAKYEGILDTNPNIQLLRGEARFKDAHTLVVTSTTGRG
ESEVSFDRCLIATGAHAAVPPIPGLKDTPYWTSTEALASDAIPPRLAVIGSSVVAVELAQAFARLGSHVTILARSSLFFR
EDPAIGEAITAAFRAEGIEVLEHTQASQVAHANGEFVLTTGHGEVRADRLLVATGRTANTRDLALEAAGVAVNAQNAIVV
DRGMRTSAPHIYAAGDCTDQPQFVYVAAAAGTRAAINLMGGEATLDLTTMPAVVFTEPQVATVGLSEAEAHLQGIETDSR
TLSLDNVPRALVNFDTHGFIKLVAEAGSGRLIGVQAVTPEAGEIIQAAALAIRARMTVQELADQLFPYLTMVEGLKLAAQ
TFTKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 74
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 73
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 73
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 73
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 72
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 6e-179 72
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 72
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 1e-177 71
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 9e-178 71
merA AFG30120.1 MerA Not tested PAGI-2 Protein 9e-178 71
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-85 46
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-85 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
R2APBS1_1852 YP_007590211.1 mercuric reductase BAC0652 Protein 1e-180 72
R2APBS1_1852 YP_007590211.1 mercuric reductase BAC0653 Protein 0.0 71
R2APBS1_1852 YP_007590211.1 mercuric reductase BAC0650 Protein 3e-170 67
R2APBS1_1852 YP_007590211.1 mercuric reductase BAC0651 Protein 2e-85 46