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Name : guaA (M1GAS476_0974) Accession : YP_007587500.1 Strain : Streptococcus pyogenes M1 476 Genome accession: NC_020540 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : - COG ID : - EC number : - Position : 924644 - 926206 bp Length : 1563 bp Strand : + Note : similiar to M5005_Spy_0919 of S. pyogenes MGAS5005 DNA sequence : ATGACTGAAATTTCAATTTTGAATGATGTTCAAAAAATTATCGTTCTTGATTATGGTAGCCAGTACAATCAGCTTATTGC TAGACGTATTCGAGAGTTTGGTGTTTTCTCCGAACTAAAAAGCCATAAAATCACCGCTCAAGAACTTCGTGAGATCAATC CCATAGGTATCGTTTTATCAGGAGGGCCTAACTCTGTTTACGCTGATAACGCCTTTGGCATTGACCCTGAAATCTTTGAA CTAGGGATTCCGATTCTTGGTATCTGTTACGGTATGCAATTAATCACCCATAAATTAGGTGGTAAAGTTGTTCCTGCTGG ACAAGCTGGTAATCGTGAATACGGTCAGTCAACCCTTCATCTTCGTGAAACGTCAAAATTATTTTCAGGCACACCTCAAG AACAACTCGTTTTGATGAGCCATGGTGATGCTGTTACTGAAATTCCAGAAGGTTTCCACCTTGTTGGAGACTCAAATGAC TGTCCCTATGCAGCTATTGAAAATACTGAGAAAAACCTTTACGGTATTCAGTTCCACCCAGAAGTGAGACACTCTGTTTA TGGAAATGACATTCTTAAAAACTTTGCTATATCAATTTGTGGCGCGCGTGGTGATTGGTCAATGGATAATTTTATTGACA TGGAAATTGCTAAAATTCGTGAAACTGTAGGCGATCGTAAAGTTCTTCTAGGTCTTTCTGGTGGAGTTGATTCTTCAGTT GTTGGTGTTCTACTTCAAAAAGCTATCGGTGACCAATTAACTTGTATTTTCGTTGATCACGGTCTTCTTCGTAAAGACGA GGGCGATCAAGTTATGGGAATGCTTGGGGGCAAATTTGGCCTAAATATTATCCGTGTGGATGCTTCAAAACGTTTCTTAG ACCTTCTTGCAGACGTTGAAGATCCTGAGAAAAAACGTAAAATTATTGGTAATGAATTTGTCTATGTTTTTGATGATGAA GCCAGCAAATTAAAAGGTGTTGACTTCCTTGCCCAAGGAACACTTTATACTGATATCATTGAGTCAGGAACAGAAACTGC TCAAACCATCAAATCACATCACAATGTGGGTGGTCTCCCCGAAGACATGCAGTTTGAATTGATTGAGCCCTTAAACACTC TTTTCAAAGATGAAGTTCGAGCGCTTGGAATCGCTCTTGGAATGCCTGAAGAAATTGTTTGGCGCCAACCATTTCCAGGT CCTGGACTTGCTATCCGTGTCATGGGAGCAATTACTGAAGAAAAACTTGAAACCGTTCGCGAATCAGACGCTATCCTTCG TGAAGAAATTGCTAAGGCTGGACTTGATCGTGACGTGTGGCAATACTTTACAGTTAACACAGGTGTCCGTTCTGTAGGCG TCATGGGAGATGGTCGTACTTATGATTATACCATCGCCATTCGTGCTATTACGTCTATTGATGGTATGACAGCTGACTTT GCTCAACTTCCTTGGGATGTCTTGAAAAAAATCTCAACACGTATCGTAAATGAAGTTGACCACGTTAACCGTATCGTCTA CGACATCACAAGTAAACCACCCGCAACAGTTGAATGGGAATAA Protein sequence : MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFE LGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSV VGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDE ASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPG PGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF AQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-174 | 69 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-174 | 69 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 4e-175 | 69 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-119 | 52 |
