Gene Information

Name : srtF (M1GAS476_0865)
Accession : YP_007587391.2
Strain : Streptococcus pyogenes M1 476
Genome accession: NC_020540
Putative virulence/resistance : Virulence
Product : lantibiotic ABC transporter ATP-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 826767 - 827513 bp
Length : 747 bp
Strand : +
Note : similiar to M5005_Spy_0808 of S. pyogenes MGAS5005

DNA sequence :
TTGTTTTGCTTACTATACACTAAACGCTCAGCAATATATAGAATGGGAGTAACTAATATGTTGAAAATACAAAATCTAAA
AAAATCTTATGGTAAGAGAACCATATTGAATAATGTCAATATGAATATTCCTAAGGGAAAAGTGTATGCTTTAATCGGTC
CAAATGGTGCTGGAAAATCAACTATTATGAAAATTTTGACAGGCTTAGTTAGTAAGACAAGTGGTTCTATTATTTTTGAA
GGTAGAGAATGGTCACGTCGGGATCTGCGAAAAATCGGGAGTATTATTGAAGAACCACCACTTTATAAAAATTTGAGTGC
TTACGATAATATGAAGGTAGTTACAACAATGCTTGGTGTTTCAGAAAGCACTATACTTCCATTATTAAATAAAGTTGGTC
TAGGAAATATTGACAAGAGACCAGTAAAACAATTTTCTCTTGGAATGAAGCAACGGTTAGGTATAGCTATCTCTTTAATA
AATTCACCTAAACTACTTATATTAGACGAACCTACTAATGGCTTGGACCCAATTGGAATTCAAGAATTAAGGGAAATTAT
AGAGTCATTTAAATCAGAAGGAATGACAATTATGATTTCAAGCCATATACTGTCAGAAGTTGAACATCTAGCTGATTTTA
TTGGATTTATCTATGAAGGAAAGATTATTCTGGAAAAAGAATATGACGGCTCTGAGAATCTTGAAGAGTTATTCAATAAT
CAAATTTTATTTGAAAAGAGGAGGTAG

Protein sequence :
MFCLLYTKRSAIYRMGVTNMLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIMKILTGLVSKTSGSIIFE
GREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVSESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLI
NSPKLLILDEPTNGLDPIGIQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIILEKEYDGSENLEELFNN
QILFEKRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
epiF YP_186701.1 epidermin immunity protein F Virulence vSa¥â Protein 4e-37 49
bsaF NP_646577.1 hypothetical protein Not tested vSa¥â Protein 4e-37 49
epiF YP_494453.1 lantibiotic epidermin immunity protein F Not tested vSa¥â Protein 4e-37 49
bsaF YP_001332745.1 lantibiotic immunity protein F Not tested vSa¥â Protein 3e-37 48
SSU05_0946 YP_001198312.1 hypothetical protein Not tested 89K Protein 5e-43 46
SSU98_0954 YP_001200512.1 hypothetical protein Not tested 89K Protein 5e-43 46
sboF YP_006309913.1 SboF Not tested FWisland_1 Protein 3e-40 46
cdd4 CAA63569.1 - Not tested PaLoc Protein 3e-40 45
SPN23F_09830 YP_002510959.1 lantibiotic transport ATP-binding protein Not tested PPI-1 Protein 3e-27 43
glrA YP_004287007.1 spermidine/putrescine import ATP-binding protein potA Not tested Not named Protein 3e-24 41