Gene Information

Name : lysS (M1GAS476_0550)
Accession : YP_007587080.2
Strain : Streptococcus pyogenes M1 476
Genome accession: NC_020540
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 498741 - 500246 bp
Length : 1506 bp
Strand : -
Note : similiar to M5005_Spy_0495 of S. pyogenes MGAS5005

DNA sequence :
TTGGAGGAAAATATGTCTAATCAACACATCGAAGAATTAAATGACCAACAGATTGTCCGTCGTGAAAAAATGACGGCGCT
GGCTGAACAAGGAATTGATCCTTTCGGTAAACGCTTTGACCGCACAGCCAATTCTGCTGAATTAAAAGAAAAGTATGCTG
ATAAAACAAAAGAAGAATTACATGAGTTAAACGAAACAGCTATTGTTGCTGGCCGCTTGATGACAAAACGTGGCAAAGGT
AAGGTTGGTTTTGCTCATCTTCAAGACCGTGAAGGCCAAATCCAACTTTATGTTCGCAAGGACTCTGTTGGCGAAGACAA
CTATGAAATCTTCAAAAAAGCCGATTTAGGCGACTTTATCGGCGTTGAAGGCGAAGTCATGCGTACAGACATGGGCGAGT
TGTCAATCAAGGCAACCAAGTTGACTCACCTTTCTAAATCACTTCGTCCTCTTCCTGAAAAATTCCACGGATTAACTGAT
ATTGAAACCATTTACCGTAAGCGTCACCTTGATTTAATTTCAAATCGTGAAAGCTTTGACCGCTTCGTGACCCGTTCCAA
AATGATTTCAGAAATCCGTCGTTATTTAGACGGTCTTGATTTCCTAGAAGTAGAAACGCCTGTGCTTCATAACGAGGCTG
GTGGTGCTGCTGCTCGTCCTTTCGTTACTCACCATAATGCTCAAAACATTGATATGGTGCTTCGTATCGCAACAGAACTT
CATTTGAAACGTTTGATTGTTGGTGGTATGGAACGTGTCTATGAAATTGGTCGTATCTTCCGTAACGAGGGAATGGATGC
TACTCATAATCCTGAGTTCACTTCTATTGAGGTTTACCAAGCCTATGCAGACTATCTTGATATCATGAACCTGACAGAAG
GCATTATCCAACATGCTGCTAAAGCTGTTAGAGGTGATGGCCCTATTGATTATCAAGGAACTGAAATCCGTATCAATGAA
CCTTTCAAACGTGTTCACATGGTAGATGCTATCAAGGAAGTGACAGGTGCTGATTTCTGGCCTGAAATGACTGTCGAAGA
AGCTATTGCACTTGCCAAAGAAAAACAGGTCCCACTCGAAAAACACTTCATAAGTGTCGGACATATCATCAACGCTTTCT
TCGAGGAATTTGTTGAAGAAACCTTGGTCCAACCAACCTTTGTGTTTGGTCATCCTGTTGAAGTATCGCCTTTGGCTAAG
AAGAATCCAGAAGATACCCGCTTCACCGACCGCTTCGAACTTTTCATCATGACCAAAGAATACGCCAATGCTTTCACAGA
GTTGAATGATCCCATTGACCAATTATCTCGTTTTGAAGCACAAGCACAAGCTAAAGAACTTGGTGATGACGAAGCAACTG
GCATTGACTACGACTTCGTTGAAGCTCTTGAATATGGTATGCCGCCAACCGGTGGACTCGGAATCGGGATTGATCGTCTT
TGCATGTTATTAACAAACACAACAACAATCAGAGATGTGCTTTTATTCCCAACGATGAAACCTTAA

Protein sequence :
MEENMSNQHIEELNDQQIVRREKMTALAEQGIDPFGKRFDRTANSAELKEKYADKTKEELHELNETAIVAGRLMTKRGKG
KVGFAHLQDREGQIQLYVRKDSVGEDNYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTD
IETIYRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFVTHHNAQNIDMVLRIATEL
HLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYLDIMNLTEGIIQHAAKAVRGDGPIDYQGTEIRINE
PFKRVHMVDAIKEVTGADFWPEMTVEEAIALAKEKQVPLEKHFISVGHIINAFFEEFVEETLVQPTFVFGHPVEVSPLAK
KNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRL
CMLLTNTTTIRDVLLFPTMKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-106 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_007587080.2 lysyl-tRNA synthetase VFG1668 Protein 3e-106 47