Gene Information

Name : M1GAS476_1919 (M1GAS476_1919)
Accession : YP_007588421.1
Strain : Streptococcus pyogenes M1 476
Genome accession: NC_020540
Putative virulence/resistance : Unknown
Product : rRNA large subunit methyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1828348 - 1828827 bp
Length : 480 bp
Strand : -
Note : similiar to M5005_Spy_1864 of S. pyogenes MGAS5005

DNA sequence :
ATGAAAGTGAAACTAATTTGTGTTGGAAAACTAAAAGAAAGATACCTCAAAGATGGTATTTCAGAATATCAAAAAAGACT
TTCCCGTTTTTGTCAATTCGAAATGATTGAGTTAACTGATGAAAGAACACCAGATAAAGCAAGTTTTGCTGATAATCAAT
TGATTATGAGTAAAGAAGCTCAGCGAATCCATAAAAAAATTGGGGAACGTGATTTTGTAATTGCATTAGCTATTGAAGGA
AAACAGTTTCCTTCAGAGACATTTAGTGAATTAATATCAGGGGTTACTGTTAAGGGATATTCAACTATCACGTTTATTAT
TGGTGGGAGTCTTGGATTAGATTCAATTATTAAAAAAAGAGCTAATATGCTAATGAGTTTTGGATTGTTAACCTTACCTC
ATCAGTTAATGCGTCTAGTCCTTACTGAGCAAATTTATCGTGCTTTTATGATTACACAAGGCAGTCCTTATCATAAGTAA

Protein sequence :
MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTPDKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEG
KQFPSETFSELISGVTVKGYSTITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orfX YP_251938.1 rRNA large subunit methyltransferase Not tested SCCmec Protein 2e-27 46
SERP2529 YP_190070.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 1e-27 45
SE0023 NP_763578.1 rRNA large subunit methyltransferase Not tested SCCpbp4 Protein 1e-27 45
unnamed BAB72138.1 open reading frame X Not tested Type-IVb SCCmec Protein 1e-27 44
unnamed BAC67575.1 open reading frame X Not tested Type-IVc SCCmec Protein 1e-27 44
orfXhom BAB83497.1 open reading frame X Not tested SCC 12263 Protein 1e-24 44
unnamed BAA82243.1 orfX Not tested Type-II SCCmec Protein 1e-27 44
orfX AAL26648.1 unknown Not tested SCCcap1 Protein 8e-27 44
unnamed BAD24821.1 conserved hypothetical protein orfX Not tested Type-V SCCmec Protein 1e-27 44
orfX BAA86653.1 open reading frame X Not tested Type-I SCCmec Protein 1e-27 44
unnamed BAG06184.1 conserved hypothetical protein orfX Not tested Type-VII SCCmec Protein 1e-27 44
unnamed BAB47681.1 open reading frame X Not tested Type-III SCCmec Protein 1e-27 44
SSP0026 YP_300116.1 rRNA large subunit methyltransferase Not tested SCC15305RM Protein 2e-27 44
unnamed BAC53844.1 open reading frame X Not tested SRImec-III and SCCmec-III region Protein 1e-27 44
SAR0024 YP_039501.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 2e-27 44
unnamed BAC57492.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 1e-27 44
SAV0024 NP_370548.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 2e-27 44
unnamed BAB72121.1 hypothetical protein Not tested Type-IVa SCCmec Protein 1e-27 44