Gene Information

Name : metB (M1GAS476_0186)
Accession : YP_007586723.2
Strain : Streptococcus pyogenes M1 476
Genome accession: NC_020540
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 150272 - 151555 bp
Length : 1284 bp
Strand : +
Note : similiar to M5005_Spy_0146 of S. pyogenes MGAS5005

DNA sequence :
GTGCCCACTACTTTTCTTTATTTTTCTTATAGGTTAGCAGATCACGCTTTTTTGAAGAGCTTTTTGGTTTGTGCAACCAT
TGGGGTGGGACCATTGTCTAAAAGAGAGTTCATTGGAGTTAACGCTATTGCGGAGGTGCACGAAATGAGAGAAAATACGA
CCTTATTACATGGCTATACGGTTATTGACGAGTTTACAGGAGCAGCTTCAGTTCCCATCTATCAGACTTCGACGTTCCAC
AATTCAGAACTGTATTGTCCTAGTCAAAAACATTTGTACACACGCTTTTCAAACCCAACGACTGAAGCTTTAGAAGACGG
GTTAGCCTGTTTAGAAAAAGCGACTTATGCGGTGGCTTATGCATCTGGTATGGCTGCTATTTCAACTGTTTTGATGCTCT
TAAAAGCTGGAGATCATGTGATTTTCCCATTGGAGGTCTATGGAGGGACTTGTCAATTTGCGACAGCTATTTTACCCAAT
TATCAGATTGAAACAAGCTTTGTAGATATGGCTGATTTAGCAACAGTAAAAGCAAGTATCAGGCCTAATACGCGTATGAT
TTATCTAGAGACACCGTCAAATCCGCTCTTGAAAATTTGTGATATTTCAGAGCTTGCGCAACTCGCCAAAGCTTATGGTG
TGCTAACTGTGGCTGATAATACCTTTATGACCAGTTTGTATCAAGAACCCTTAGCTATGGGTGTGGATATTGTAGTAGAA
AGTGTGACCAAATTTATCAATGGTCATAGTGATGTGGTAGCTGGTTTAGCTGCTACCAATAATGAGGCTATCTACAACCA
GCTCAAGCTTTTTCAAAAAAACTTTGGAGCAATTGTTGGGGTCGAAGACGCTTGGCTGATTCTTCGTGGCATGAAAACTA
TGGGGATCCGTATGGAACAAGCGGTAAAAAATGCTCAGCAGCTCGCTAACTATTTAGCGAAGCACCCCAAAGTTCTTAAG
GTACATTACCCTGGCTTAGACAGTCATCCTAATCACGATACCCACCTGCAACAAGCTAAGAATGGTGGTGCTGTTTTATC
CTTTGAGTTGGCTTCTAAGGAGGAGCTGATGTCCTTTACCCATCGTATTCAGTTGCCGATTTTAGCCGTTAGTCTAGGTG
GAGTAGAGTCCATTTTGTCACATCCAGCAACGATGTCTCATGCTTGTTTATCGTCACAAGCGCGGTTGGAACAAGGGGTT
GTTGATGGTTTGCTGCGCTTGTCTTGTGGTGTTGAAAATATCGAAGACTTATTGGCCGATTTTGAGCAAGCACTTGCTTT
TTAA

Protein sequence :
MPTTFLYFSYRLADHAFLKSFLVCATIGVGPLSKREFIGVNAIAEVHEMRENTTLLHGYTVIDEFTGAASVPIYQTSTFH
NSELYCPSQKHLYTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGTCQFATAILPN
YQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELAQLAKAYGVLTVADNTFMTSLYQEPLAMGVDIVVE
SVTKFINGHSDVVAGLAATNNEAIYNQLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLK
VHYPGLDSHPNHDTHLQQAKNGGAVLSFELASKEELMSFTHRIQLPILAVSLGGVESILSHPATMSHACLSSQARLEQGV
VDGLLRLSCGVENIEDLLADFEQALAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 0.0 99
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-77 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-77 43