Gene Information

Name : ir (M1GAS476_1776)
Accession : YP_007588282.1
Strain : Streptococcus pyogenes M1 476
Genome accession: NC_020540
Putative virulence/resistance : Resistance
Product : two-component response regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1683349 - 1684002 bp
Length : 654 bp
Strand : -
Note : similiar to M5005_Spy_1725 of S. pyogenes MGAS5005

DNA sequence : 
ATGTTTAAAATATTAGTAGTTGAAGATGATGATACCATCAGTCAAGTGATTTGTGAGTTTTTAAAAGCGAATAACTATGA
TCCAGATTGTGTATTTGATGGCCAAGCTGCCTTAGACAAGTGGCAGACAACGTCTTATGATCTGATTATTTTAGACATCA
TGCTCCCTTCCTTAAGTGGCTTAGAAGTGCTAAAAACAATTCGAAAGACATCAGATGTCCCTATTATTATGCTAACGGCA
TTAGATGACGAGTACACACAGCTTGTAAGCTTCAACCATTTGATTAGTGATTATGTGACCAAACCATTTTCACCACTCAT
TTTAATCAAACGTATCGAAAATGTATTACGCGTCTCTACTCCAGATGAAAAGCGCCAAATCGGAGACTTACTTGTTGATG
AGACCGAACATAGCGTCTATTGGCAAGGAACATTGGTCAAACTAACCAAAAAAGAATATGACATTATTGATTATTTAGCA
AAACGTCACCAAAAAATTGTCACCAGAGACCAATTGATGGATGACATATGGGGCTATTCTGAACTGGACACGCGTGTCCT
TGACAACCACATCAAGAACCTTCGTAAAAAAATGACGGGTATTCCCCTCAAGACAATTACAGGCATGGGCTATTTATTGG
GAGAGCGTGAGTGA

Protein sequence : 
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTA
LDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-34 41
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 6e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ir YP_007588282.1 two-component response regulator AF310956.2.orf0.gene Protein 9e-35 41
ir YP_007588282.1 two-component response regulator AE016830.1.gene2255. Protein 2e-34 41
ir YP_007588282.1 two-component response regulator U35369.1.gene1.p01 Protein 2e-34 41