Gene Information

Name : tkt (M1GAS476_1453)
Accession : YP_007587967.2
Strain : Streptococcus pyogenes M1 476
Genome accession: NC_020540
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1363707 - 1365896 bp
Length : 2190 bp
Strand : -
Note : similiar to M5005_Spy_1375 of S. pyogenes MGAS5005

DNA sequence :
GTGGCCACTGTGTCAACAGGCTCTCTTATATTCATCGTCAAAAAGAATCCATCAATGATGTCCAAACTAGTTTTTTTCTG
GCAAAATAGAGAAAAAGAATTTAGGGACTTTGGAGGATTTTCTGAAAAAAGCGTCTATTTTTGTGATACAATAGACAATA
GAAAACGTTTAATTTTAGTTGTAATAAACAGAGAGGTTTTACTTATGACATTTGATGCAATTGACCAGTTGGCAGTAAAC
ACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTCTGGACACCCAGGACTTCCAATGGGGGCAGCACCTAT
GGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAACAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCC
TATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACACTTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAG
AACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGTGAACCACACAGACGGTGTCGAAGCAACCACAGGACC
TCTTGGTCAAGGGATCGCAAATGCCGTTGGGATGGCCATGGCAGAAGCTCATCTAGCAGCTAAATTTAACAAACCAGGCT
TTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGTGACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGT
ATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGATTCAAACGACATCTCTCTTGATGGTCCAACCTCTAT
GGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTTGGCAACATATCCTTGTGAAAGATGGAAATGATTTAG
AAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAGAAACCAACCATCATCGAAGTCAAAACCATTATTGGT
TTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCCTCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGC
TTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAACAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTG
AAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAAGCAGAATATCCAGAATTAGCAGCAGAATACCAAAAA
GCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGAACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCA
ACAAGCCATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGGGTGGGTCAGCAGACCTTTCAGCTTCAAACAATACTA
TGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGCCGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATG
GCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGTTTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCT
TCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAGTTTATGTCATGACACATGATTCTATCGCTGTCGGTG
AAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTTCGCTCAATGCCTAACTTGAACGTTATTCGTCCAGCA
GACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGAAACAGATCGCCCAACCATGCTTGTATTGACGCGTCA
AAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATGGTCTTAGCAAAGGAGCTTATATCTTGTCAGAAGCCA
AAGGCGACCTTGATGGTATCTTGATTGCAACAGGTTCAGAAGTGAAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCA
GAAGGCATTCATGTGCGTGTCGTATCTATGCCATCACAAAATATCTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCAT
CCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTTCAAGCTTTGGCTGGGCAAAATATGTCGGCCTATCAG
GAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGAAATCGTATCTTCGAAGAATATGGTTTCACTGTGGCA
AATGCAACTGAGTTATACAAATCACTCTAA

Protein sequence :
MATVSTGSLIFIVKKNPSMMSKLVFFWQNREKEFRDFGGFSEKSVYFCDTIDNRKRLILVVINREVLLMTFDAIDQLAVN
TVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLK
NFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDGDLMEGVSQEAAS
MAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIG
FGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQK
AFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEGRNIWFGVREFAM
AAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPA
DGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLSKGAYILSEAKGDLDGILIATGSEVKLAMDTQEALEA
EGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLSGKTLTIDTWGASAPGNRIFEEYGFTVA
NATELYKSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 8e-127 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 4e-125 49